Version 2.80

Description

Vitamin K antagonist therapy causes a decrease in the active forms of coagulation factors II, VII, IX, and X, with a concomitant increase in non-functional forms of these factors. These non-functional proteins are called "proteins induced by vitamin K absence/antagonism", or PIVKA, and can act as competetive inhibitors of thromboplastin, depending on the source. Human recombinant and bovine thromboplastins are sensitive to PIVKA, while rabbit thromboplastin is not. PMID: 24045543 Prothrombin time (PT) assays that use PIVKA-sensitive thromboplastin are considered to be more sensitive to factor II, VII and X deficiencies compared to standard PT assays. [http://www.eclinpath.com/hemostasis/tests/screening-coagulation-assays/] Source: Regenstrief LOINC

Basic Part Properties

Part Name
Coagulation tissue factor induced.PIVKA sensitive
Part Display Name
Prothrombin time (PT) PIVKA sensitive
Part Type
Component (Describes the core component or analyte measured)
Created On
2008-04-09
Construct for LOINC Short Name
PT PIVKA sensitive

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP69240-7

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Tiempo de protrombina (PT) PIVKA sensible
it-IT Italian (Italy) Coagulazione indotta da fattore tissutale.PIVKA sensibile
Synonyms: Tempo di Protrombina (PT) PIVKA sensibile
tr-TR Turkish (Turkey) Koagülasyon dokusu faktör uyarılmış.PIVKA'ya duyarlı sensitive
ru-RU Russian (Russian Federation) Коагуляция тканевым фактором индуцированная.PIVKA чувствительный
Synonyms: Протромбиновое время (ПВ) PIVKA чувствительное
fr-BE French (Belgium) Facteur de coagulation tissulaire.sensible à PIVKA
nl-NL Dutch (Netherlands) protrombinetijd.PIVKA-gevoelig
pl-PL Polish (Poland) Białka indukowane niedoborem witaminy K (PIVKA) tromboplastyny wrażliwe
zh-CN Chinese (China) 组织因子诱导型凝血过程.PIVKA 敏感性
Synonyms: protein induced by vitamin K absence or antagonist;维生素K缺乏(或拮抗)诱导蛋白;protein-induced by vitamin K absence;维生素K缺乏诱导的蛋白;protein-induced by vitamin K antagonist;维生素K拮抗剂诱导的蛋白;PIVKA;Prothrombin time;PT;凝血酶原时间;PIVKA 敏感性凝血酶原时间
el-GR Greek (Greece) Πήξη επαγόμενη από ιστικό παράγοντα.ευαίσθητη σε PIVKA
Synonyms: Πήξη επαγόμενη από ιστικό παράγοντα.ευαίσθητη σε PIVKA