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Arachidonate (AA) is an essential polyunsaturated omega-6 fatty acid that is produced from dietary linoleic acid. AA is located in human fat, liver, brain, and glandular organs and is a mediator of inflammation. The AA within the phospholipids of cell membranes is the surface where the production of a number of biologically active compounds occurs. A few of the compounds produced includes prostaglandins, thromboxanes, and leukotrienes which regulate processes including platelet aggregation, blood clotting, smooth muscle contraction, leukocyte chemotaxis, inflammatory cytokine production, and immune function.[PubChem: 444899] AA is released from the cell membrane when acted upon by phospholipases and then metabolized by cyclooxygenase (COX) producing the prostanoids prostaglandin and thromboxane A2, which can stimulate or mitigate inflammation. PMID: 21508345 One of the benefits of the Omega-3 fatty acids for patients with inflammatory disease is believed to be their selective modification of the metabolism of AA by the omega-3 fatty acids that results in a reduced amount of inflammation. PMID: 23371504 Source: Regenstrief LOINC

Basic Part Properties

Part Display Name
Arachidonate (C20:4w6)
Part Type
Divisors (Divisors only)
Created On
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Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 花生四烯酸
Synonyms: 花生四烯酸 (C20:0)
fr-CA French (Canada) Arachidonate
et-EE Estonian (Estonia) arahhidonaat
es-ES Spanish (Spain) Araquidonato
it-IT Italian (Italy) Arachidonato
Synonyms: Arachidato (C20:0)
tr-TR Turkish (Turkey) Araşidonat
ru-RU Russian (Russian Federation) Арахидонат
Synonyms: Арахидонат (C20:0)
nl-NL Dutch (Netherlands) arachidonaat
Synonyms: arachidonzuur
fr-BE French (Belgium) Arachidonate
pl-PL Polish (Poland) kwas arachidonowy