LP69948-5
Arachidonate
Active
Description
Arachidonate (AA) is an essential polyunsaturated omega-6 fatty acid that is produced from dietary linoleic acid. AA is located in human fat, liver, brain, and glandular organs and is a mediator of inflammation. The AA within the phospholipids of cell membranes is the surface where the production of a number of biologically active compounds occurs. A few of the compounds produced includes prostaglandins, thromboxanes, and leukotrienes which regulate processes including platelet aggregation, blood clotting, smooth muscle contraction, leukocyte chemotaxis, inflammatory cytokine production, and immune function.[PubChem: 444899] AA is released from the cell membrane when acted upon by phospholipases and then metabolized by cyclooxygenase (COX) producing the prostanoids prostaglandin and thromboxane A2, which can stimulate or mitigate inflammation. PMID: 21508345 One of the benefits of the Omega-3 fatty acids for patients with inflammatory disease is believed to be their selective modification of the metabolism of AA by the omega-3 fatty acids that results in a reduced amount of inflammation. PMID: 23371504 Source: Regenstrief LOINC
Basic Part Properties
- Part Display Name
- Arachidonate (C20:4w6)
- Part Type
- Divisors (Divisors only)
- Created On
- 2008-05-02
- Construct for LOINC Short Name
- AA
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 花生四烯酸 Synonyms: 花生四烯酸 (C20: |
| fr-CA | French (Canada) | Arachidonate |
| et-EE | Estonian (Estonia) | arahhidonaat |
| es-ES | Spanish (Spain) | Araquidonato |
| it-IT | Italian (Italy) | Arachidonato Synonyms: Arachidato (C20: |
| tr-TR | Turkish (Turkey) | Araşidonat |
| ru-RU | Russian (Russian Federation) | Арахидонат Synonyms: Арахидонат (C20: |
| nl-NL | Dutch (Netherlands) | arachidonaat Synonyms: arachidonzuur |
| fr-BE | French (Belgium) | Arachidonate |
| pl-PL | Polish (Poland) | kwas arachidonowy |
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