LP71704-8
Human upstream binding factor
Active
Description
Human upstream binding factor (hUBF) is a nucleolar protein that plays a key role in rRNA production. The protein regulates rDNA transcription and also promotes rRNA synthesis. DNA binding to hUBF has the potential to alter chromatin by inducing chromatin remodeling. PMID: 25965800 Autoantibodies to hUBF (anti-hUBF) are associated with various connective tissue diseases, including systemic sclerosis, Raynaud's disease, rheumatoid arthritis and systemic lupus erythematosus. Anti-hUBF antibodies have also been associated with some malignancies. Anti-hUBF and anti-nucleolus-organizing region (NOR) 90 antibodies were originally described as distinct entities but later were recognized as being the same. PMID: 20175839 Source: Regenstrief LOINC, PMID: 20175839
Basic Part Properties
- Part Display Name
- Human upstream binding factor
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2008-10-30
- Construct for LOINC Short Name
- hUBF
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=LP71704-8
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 人上游结合因子 Synonyms: 人上遊結合因子; |
| fr-CA | French (Canada) | NOR-90 |
| et-EE | Estonian (Estonia) | NOR-90 |
| es-ES | Spanish (Spain) | factor de unión upstream humano |
| it-IT | Italian (Italy) | Fattore umano a monte legante Synonyms: hUBF |
| tr-TR | Turkish (Turkey) | Human upstream bağlayıcı factor |
| ru-RU | Russian (Russian Federation) | Человеческий upstream binding factor |
| nl-NL | Dutch (Netherlands) | Humaan upstream binding factor |
| fr-BE | French (Belgium) | Human upstream binding factor |
LOINC Copyright
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