LP99923-2

2-Ketobutyrate

Active

Description

2-Ketobutyric acid is a substance that is involved in the metabolism of many amino acids (glycine, methionine, valine, leucine, serine, threonine, isoleucine) as well as propanoate metabolism and C-5 branched dibasic acid metabolism. More specifically, alpha-ketobutyric acid is a product of the lysis of cystathionine. It is also one of the degradation products of threonine. It can be converted to propionyl-CoA (and subsequently methylmalonyl CoA, which can be converted to succinyl CoA, a citric acid cycle intermediate), and thus enter the citric acid cycle. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, 2-Ketobutyrate

Basic Part Properties

Part Name

2-Ketobutyrate

Part Display Name

2-Ketobutyrate

Part Type

Component (Describes the core component or analyte measured)

Created On

2010-03-25

Construct for LOINC Short Name

2-Ketobutyrate

Related Codes

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