78993-3
Prolactin isoforms panel - Serum or Plasma
Active
Term Description
The prolactin isoforms panel includes individual tests for monomeric, dimeric, and macroprolactin, as well as fraction terms for each isomer and an interpretation based on all of the results. Monomeric prolactin is the most common form of circulating prolactin. The dimeric form ("big-prolactin") has a molecular weight of ~50 kD, and polymeric form ("big-big prolactin") has a molecular weight of ~ 150 kD). Big-big prolactin, known as macroprolactin, and big prolactin are formed in the circulation after secretion of prolactin from the pituitary. They have a longer half-life than monomeric prolactin and are not biologically active. However, typical prolactin assays do not differentiate between the different forms of prolactin, and the presence of big and big-big prolactin can lead to a false diagnosis of hyperprolactinemia. Methods such as PEG precipitation can separate macroprolactin and big prolactin from monomeric prolactin in order to obtain a more accurate measurement of biologically active prolactin, and chromatography can be used to further characterize the isoforms if necessary. PMCID: PMC3719302
Panel Hierarchy
Details for each LOINC in Panel LHC-Forms
| LOINC | Name | R/O/C | Cardinality | Example UCUM Units |
|---|---|---|---|---|
| 78993-3 | Prolactin isoforms panel - Serum or Plasma | |||
| Indent15081-3 | Prolactin [Units/volume] in Serum or Plasma | m[IU]/L | ||
| Indent78994-1 | Prolactin monomeric [Units/volume] in Serum or Plasma | [arb'U]/L | ||
| Indent78995-8 | Prolactin monomeric/Prolactin in Serum or Plasma | % | ||
| Indent78985-9 | Prolactin.dimeric [Units/volume] in Serum or Plasma | [arb'U]/L | ||
| Indent78986-7 | Prolactin.dimeric/Prolactin in Serum or Plasma | % | ||
| Indent74953-1 | Macroprolactin [Units/volume] in Serum or Plasma | [arb'U]/L | ||
| Indent78984-2 | Macroprolactin/Prolactin in Serum or Plasma | % | ||
| Indent79398-4 | Prolactin isoforms pattern [Interpretation] in Serum or Plasma Narrative |
LOINC Names Get Info
- Fully-Specified Name
- Prolactin isoforms panel:
-: Pt: Ser/Plas: -: - Long Common Name
- Prolactin isoforms panel - Serum or Plasma
- Short Name
- Prolactin isoforms Pnl SerPl
- Display Name
- Prolactin isoforms panel
- Consumer Name Alpha Get Info
- Prolactin isoforms panel, Blood
Part Model Get Info
- Component
- Prolactin isoforms panel
LP200142-0
- Analyte
- Prolactin isoforms panel
LP200142-0
- Component Numerator
- Prolactin isoforms panel
LP200142-0
- Component Numerator Core
- Prolactin isoforms panel
LP200142-0
- Component Numerator Core Suffix
- NULL
- Component Denominator
- NULL
- Component Denominator Core
- NULL
- Component Denominator Core Suffix
- NULL
- Challenge
- NULL
- Adjustment
- NULL
- Count
- NULL
- Property
- -
LP6769-6
- Time
- Pt
LP6960-1
- Time Core
- Pt
LP6960-1
- Time Modifier
- NULL
- System
- Ser/Plas
LP7576-4
- System Core
- Ser/Plas
LP7576-4
- Super System
- NULL
- Scale
- -
LP7747-1
- Method
- NULL
Basic Attributes
- Class
- PANEL.CHEM
- Type
- Laboratory
- First Released
- Version 2.54
- Last Updated
- Version 2.54 (MIN)
- Order vs. Observation
- Order
- Panel Type
- Panel
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Prolaktin izoformy panel: |
| el-GR | Greek (Greece) | Πίνακας ισομορφών προλακτίνης: Synonyms: - CHEM PANEL.CHEM Pt Ορός Ορός/Πλάσμα Πίνακας ισομορφών προλακτίνης Πλάσμα Προλακτίνη |
| es-ES | Spanish (Spain) | Panel isoformas prolactina: |
| es-MX | Spanish (Mexico) | Panel de isoformas de prolactina: |
| fr-FR | French (France) | Prolactines isoformes panel: |
| it-IT | Italian (Italy) | Isoforme della prolattina, panel: Synonyms: Chimica Panel isoforme della prolattina Plasma Punto nel tempo (episodio) Set di prescrizione chimica Siero Siero o Plasma |
| nl-NL | Dutch (Netherlands) | prolactine isovormen panel: |
| pl-PL | Polish (Poland) | Panel izoform prolaktyny: |
| zh-CN | Chinese (China) | 催乳素同工型组套: Synonyms: PRL; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=78993-3 - Questionnaire definition
- https:
//fhir.loinc.org/Questionnaire/?url=http: //loinc.org/q/78993-3
LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://