79190-5

Zika virus RNA [Presence] in Specimen by NAA with probe detection

Active

Term Description

Possible test specimens include: cord blood, blood from the heart postmortem, venous blood, CSF (both fluid and swabs), serum or plasma, (with serial testing of serum for acute and convalescent samples), and mosquitoes.

Part Descriptions

LP200137-0 Zika virus
Zika virus (ZIKV) is a flavivirus transmitted primarily by the Aedes mosquito which was first identified in a sentinel monkey in the Zika forest in Uganda in 1947. Since 2014 it has spread explosively in the Americas where it has infected hundreds of thousands of people. About 80% of those infected are asymptomatic. Common symptoms include fever, headache, rash, arthralgia and conjunctivitis. Since the end of 2015, there has been an increase in ZIKV-associated cases of Guillain-Barre syndrome and a tremendous increase in cases of microcephaly in fetuses and newborns in Brazil, raising worldwide public health concern. Recent predictions are that the mosquito species A. Albopictus, which can hibernate and survive cool temperatures, will carry ZIKV to more temperate areas of North America, Australia and Southern Europe. It is still not clear whether ZIKV in humans increases viral titers enough to trigger a new cycle when an infected person is bitten by a naïve mosquito. Direct human-to-human transmission has been documented to occur perinatally, sexually (primarily through semen), through breastfeeding, blood transfusion and through occupational transmission in the laboratory setting. There are currently no specific anti-viral agents, vaccination or medical prophylaxis available. PMID: 27148186 Source: Regenstrief LOINC

LP203271-4 Zika virus RNA
Zika virus contains an inner nucleocapsid composed of RNA and multiple copies of the viral capsid (C) protein. The outer host contains 180 copies each of two proteins: the viral membrane (M) protein and the envelope (E) protein (Kostyuchenko et al., 2016; Sirohi et al., 2016). Viral RNA of the Zika virus has been identified in the brain and liver of fetuses and in the brain, eyes, spleen, liver and placenta of pregnant mothers, with the highest viral load existing in the placenta.(Adams Waldorf et al., 2016). Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Zika virus RNA:PrThr:Pt:XXX:Ord:Probe.amp.tar
Long Common Name: Zika virus RNA [Presence] in Specimen by NAA with probe detection
Short Name: ZIKV RNA Spec Ql NAA+probe
Display Name: ZIKV RNA NAA+probe Ql (Specimen)
Consumer Name Alpha Get Info: Zika virus, Specimen

Part Model Get Info

Component
Zika virus RNA
LP203271-4
- Analyte
  Zika virus RNA
  LP203271-4
  - Component Numerator
    Zika virus RNA
    LP203271-4
    - Component Numerator Core
      Zika virus
      LP200137-0
    - Component Numerator Core Suffix
      RNA
      LP32423-3
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
PrThr
LP217195-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
XXX
LP7735-6
- System Core
  XXX
  LP7735-6
- Super System
  NULL
Scale
Ord
LP7751-3
Method
Probe.amp.tar
LP6464-4

Example Answer List: LL3698-9

Source: Association of Public Health Laboratories

Answer	Code	Score	Answer ID
Detected			LA11882-0
Not detected			LA11883-8
EquivocalCopyright http://snomed.info/sct ID:42425007 Equivocal (qualifier value)			LA11885-3
InconclusiveCopyright http://snomed.info/sct ID:419984006 Inconclusive (qualifier value)			LA9663-1
Not tested			LA13538-6

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.54
Last Updated: Version 2.73 (MIN)
Change Reason: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation: Both
Common Test Rank Get Info: 5843

Member of these Groups Get Info

LOINC Group	Group Name
LG32774-8	Zika virus

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Virus Zika RNA:Přítomnost nebo práh:Časový bod:XXX:Ordinální:Amplifikace nukleových kyselin s detekcí sondou
de-DE	German (Germany)	Zika-Virus RNA:Nachweis oder Schwellenwert:Zeitpunkt:XXX:Ordinal:Zielfragmentamplifikation mit Sondendetektion
el-GR	Greek (Greece)	Ιός Ζίκα RNA:PrThr:Pt:XXX:Ord:Ανιχνευτής.ενίσχυση.στόχου Synonyms: MICRO Ord PrThr Pt RNA XXX Ανιχνευτής Ανιχνευτής.ενίσχυση Ανιχνευτής.ενίσχυση.στόχου Ιός Ιός Ζίκα
es-ES	Spanish (Spain)	Virus Zika RNA:PrThr:Punto temporal:XXX:Ord:Sonda con amplificación dirigida
es-MX	Spanish (Mexico)	ARN del virus del Zika:Presencia o umbral:Punto temporal:XXX:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
fr-FR	French (France)	Zika virus ARN:Présence/Seuil:Ponctuel:Milieux divers:Qualitatif:PCR amplification de cible
it-IT	Italian (Italy)	Zika virus RNA:PrThr:Pt:XXX:Ord:Sonda.amp.tar Synonyms: Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA Virus Zika
nl-NL	Dutch (Netherlands)	zikavirus RNA:aanwezigheid:moment:XXX:ordinaal:probe-detectie Synonyms: probe.amp.tar Zika-virus
pl-PL	Polish (Poland)	Wirus Zika RNA:granica wykrywalności:punkt w czasie:XXX:uporządkowany:sonda.amplifikacja.cel Synonyms: amplifikacja kwasu nukleinowego z detekcją za pomocą sondy amplifikacja z detekcją za pomocą sondy
tr-TR	Turkish (Turkey)	Zika virüs RNA:MevcEşik:Zmlı:XXX:Srl:Prob.amf.hdf Synonyms: Mevcut
zh-CN	Chinese (China)	寨卡病毒 RNA:存在情况或阈值:时间点:XXX:序数型:探针法.基因扩增.靶向 Synonyms: 不明的;其他;将在相应消息内其他部分之中加以详细说明;未作详细说明的;未作说明的;未做说明的标本;未加规定的;未加说明的标本;杂项传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型借助扩增的探针方法;借助扩增的探针法;探针法.扩增借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向塞卡病毒;Zika virus;Zika 病毒;ZIKV;济卡病毒;兹卡病毒存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）扩增型扩增性时刻;随机;随意;瞬间核糖核酸;Ribonucleic acid 经过扩增的脱氧核糖核酸探针

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CodeSystem lookup: https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=79190-5

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.