LOINC
Version 2.73

100675-8Cytomegalovirus DNA [Units/volume] (viral load) in Blood by NAA with probe detectionActive

Part Description

LP14255-1   Cytomegalovirus
Cytomegalovirus is a member of the family Herpesviridae and also known as Human Herpesvirus-5 (HHV-5). It contains a linear double-stranded DNA encased in an icosahedral capsid that is surrounded by a viral envelope. It replicates slowly and may take weeks for the infection to become visible microscopically. Its life cycle includes a lytic and a latent phase. During the lytic phase the cytoskeleton of the infected cell is disrupted and becomes very large. The enlarged cell eludes detection by natural killer (NK) cells by encoding UL16. UL16 is a protein that binds to the ligand NDG2D which is a surface receptor on NK cells and, when blocked, prevents the CMV infected cell from apoptotic signaling to NK cells to destroy it.[https://pedclerk.bsd.uchicago.edu/page/cytomegalovirus-cmv] In the US one in three children are infected by CMV by the age of five and over half of adults are infected by age 40. Infection with CMV is mostly asymptomatic. Symptoms when present include fever, sore throat, fatigue, swollen glands. CMV can occasionally lead to mononucleosis or hepatitis. Immunocompromised patients experience much more acute symptoms that can affect the eyes, lungs, liver, esophagus, stomach, and intestines. For babies born with CMV, involvement with the brain, spleen, lung, liver can occur. In addition, there may be growth problems and hearing loss which is the most common symptom in congenital CMV infection. CMV is transmitted in urine, saliva, blood, tears, semen and breast milk by direct contact. Normally no treatment is necessary, but for severe cases medication is available.[https://www.cdc.gov/cmv/overview.html] Source: Regenstrief LOINC

Fully-Specified Name

Component
Cytomegalovirus DNA
Property
ACnc
Time
Pt
System
Bld
Scale
Qn
Method
Probe.amp.tar

Additional Names

Short Name
CMV DNA Bld NAA+probe-aCnc
Display Name
CMV DNA NAA+probe Qn (Bld)
Consumer Name Alpha
Cytomegalovirus (CMV), Blood

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.73
Last Updated
Version 2.73
Order vs. Observation
Both

Language Variants Get Info

zh-CNChinese (China)
巨细胞病毒 DNA:任意型浓度:时间点:全血:定量型:探针法.基因扩增.靶向
nl-NLDutch (Netherlands)
Cytomegalovirus DNA:eenheid/volume:moment:bloed:kwantitatief:moleculaire techniek (PCR)
fr-BEFrench (Belgium)
Cytomégalovirus ADN:Concentration arbitraire:Temps ponctuel:Sang:Quantitatif:Sonde avec amplification de la cible
fr-CAFrench (Canada)
Cytomégalovirus , ADN:Concentration arbitraire:Temps ponctuel:Sang:Quantitatif:Sonde avec amplification de la cible
it-ITItalian (Italy)
Citomegalovirus DNA:ACnc:Pt:Sangue:Qn:Sonda.amp.tar
ru-RURussian (Russian Federation)
Цитомегаловирус ДНК:ПроизвКонц:ТчкВрм:Кр:Колич:Проба.усил.миш
es-ESSpanish (Spain)
Citomegalovirus ADN:Concentración arbitraria:Punto temporal:Sangre:Qn:Sonda con amplificación dirigida
tr-TRTurkish (Turkey)
Cytomegalovirus DNA:SçKons:Zmlı:Kan:Kant:Prob.amf.hdf

Example Units

Unit Source
[IU]/mL Example UCUM Units

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=100675-8