100789-7
Rhizopus nigricans IgG4 Ab [Mass/volume] in Serum
Active
Part Descriptions
LP17062-8 Rhizopus nigricans
Rhizopus nigricans is a fungus commonly known as bread mold and is the most common species of Rhizopus. It is found on old food and in soils and even in children's sandboxes. The genus contains some 50 species and bread mold is sometimes confused with species of Mucor or other species of Rhizopus like Rhizopus oryzae. The spores, dispersed in hot dry weather, contain allergenic proteins with 31 distinct allergens, which can produce respiratory and nasal symptoms in concentration (chronic cough, dyspnea, chest tightness, chronic phlegm, snuffle, snizzle and allergic rhinitis). Food handling workers are particularly at risk if they are mold allergic.
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Source: Wikipedia, Wikipedia
LP17062-8 Rhizopus nigricans
Rhizopus is frequently isolated from both forest and cultivated soils. It occurs in children's sandboxes. Typical microhabitats include fresh or decaying litter such as pine needles and leaves. Other known substrates are sweet potato, cold-stored strawberries, stewed fruits, and the nests, feathers and droppings of wild birds. The risk for occupational exposure is most likely to occur among food handlers during the storage, transfer and marketing of strawberries, peaches, cherries, corn and peanuts.
Rhizopus nigricans is responsible for opportunistic infections and hypersensitivity reactions such as symptoms of asthma and hypersensitivity pneumonitis in sensitised individuals, and is an important occupational allergen.
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Source: ImmunoCap, ImmunoCap
LP32397-9 Ab.IgG4
IgG4 is the least common subtype of IgG, and it has a variety of functions. In the context of allergic disease it is thought to have an immune-inhibitory role in preventing anaphylaxis and is commonly known as a "blocking" antibody. IgG4 binding to an allergen can compete with IgE-mediated binding, thereby inhibiting the activation of mast cells and basophils and IgE-mediated presentation to T-cells. Measuring IgG4 and its ratio to IgE has a role in monitoring allergen specific immunotherapy PMID: 26023323. IgG4 is also thought to have a role in autoimmunity and be involved in a less defined entity known as IgG4-Related Disease, a chronic immune-mediated fibroinflammatory disorder that often manifests with tumor-like masses .[https://www.merckmanuals.com/professional/musculoskeletal-and-connective-tissue-disorders/igg4-related-disease/igg4-related-disease]
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Rhizopus nigricans Ab.IgG4
- Property
- MCnc
- Time
- Pt
- System
- Ser
- Scale
- Qn
- Method
Additional Names
- Short Name
- R nigricans IgG4-mCnc
- Display Name
- Rhizopus nigricans IgG4 (S) [Mass/Vol]
- Consumer Name Alpha Get Info
- Rhizopus nigricans IgG4 antibody
Basic Attributes
- Class
- ALLERGY
- Type
- Laboratory
- First Released
- Version 2.73
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Rhizopus nigricans Moho IgG4: Synonyms: Cuantitativo |
et-EE | Estonian (Estonia) | Rhizopus nigricans antikehad.IgG4: Synonyms: Juhuslik Kvantitatiivne Seerum |
fr-CA | French (Canada) | Rhizopus nigricans, IgG4: |
fr-BE | French (Belgium) | Rhizopus nigricans Anticorps. IgG4: Synonyms: Anticorps m11 |
fr-FR | French (France) | Rhizopus nigricans Ac IgG4: |
it-IT | Italian (Italy) | Rhizopus nigricans Ab.IgG4: Synonyms: Anticorpi IgG4 anticorpo Concentrazione di Massa Punto nel tempo (episodio) Risposta agli antigeni Siero |
nl-NL | Dutch (Netherlands) | Rhizopus nigricans As.IgG4: Synonyms: antistof; |
ru-RU | Russian (Russian Federation) | Rhizopus nigricans Ат.IgG4: Synonyms: Антитело Количественный Массовая концентрация Сыворотка Точка во времени; |
tr-TR | Turkish (Turkey) | Rhizopus nigricans Ab.IgG4: Synonyms: Ak Ak.IgG4 |
zh-CN | Chinese (China) | 黑根霉 抗体.IgG4: Synonyms: Ab.IgG4; |
Example Units
Unit | Source |
---|---|
mg/L | Example UCUM Units |
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