Version 2.77

Status Information

Status
TRIAL

Part Descriptions

LP17728-4   Cells.CD3+CD8+
HIV infection decreases the number of CD3+ CD4+ lymphocytes (also called CD4 T cells or T4 helper cells) while increasing (momentarily) the numbers of CD3+CD8+ lymphocytes (called CD8 T lymphocytes or cytotoxic T cells). Thus the ratio of CD4/CD8 lymphocytes is decreased. These counts are used for prognostic purposes and to guide in the retroviral therapy. CDC has emphasized since 1997 that the number of CD3+ lymphocytes is necessary in addition to the number of CD4+ cells to reliably identify the T4 helper cells and the number of CD8+ cells. Laboratory reports that include only CD4 or only CD8 in their nomenclature are most likely really measuring CD3+CD4+ cells and CD3+CD8+ cells, respectively. Source: Regenstrief Help

LP17728-4   Cells.CD3+CD8+
HIV infection decreases the number of CD4 T-cells, also called T4 helper cells, the ratio of CD4 to CD8 T-cells and the number of CD8+ T-cells. These counts are ordered frequently to guide decisions about anti-retroviral therapy. Laboratories usually report both percentage and absolute count. When you map CD4 and CD8 markers, be careful! Since at least 1997, CDC has required the detection of both CD3+ and CD4+ to identify T4 helper cells, because the CD3 marker is needed to identify T-cell . So, any tests that report T4 helper cells are really reporting cells that carry BOTH the CD3+ and the CD4+ markers. The measure name may be CD3+ CD4+ cells, CD4+ marker, T4 cells or even just CD4+ (a misnomer). Exactly analogous rules apply to CD8+. Measures that include only CD4 or only CD8 in their name are really measuring CD3+CD4+ cells or CD3+CD8+ cells, respectively and should be reported with the LOINC code that includes both of those markers. The panel named T cell subsets will usually contain both CD3 + CD4 and CD3 + CD8 counts. These names assume that one has already gated to lymphocytes only. Lymphocytes are identified by CD45 markers. So a CD45+CD3+CD4+ is a more complicated way to name CD3+C4+ cells and in the context of looking for CD4 helper T cells they are the same . The same applies to other flow cytometer measures that are looking only at lymphocytes (B-cells, NK cells, etc). Source: Regenstrief Help

LP17729-2   CD8
Found on T-suppressor/cytotoxic cells and some Natural Killer cells; Associated with some mature T-cell neoplasms; Large granular lymphocytosis Source: Regenstrief LOINC

Fully-Specified Name

Component
Cells.CD3+CD8+/100 cells
Property
NFr
Time
Pt
System
Bld MC
Scale
Qn
Method

Additional Names

Short Name
CD3+CD8+ Cells Bld MC-NFr
Display Name
CD3+CD8+ (T8 suppressor) cells/100 cells (Bld MC)
Consumer Name Alpha Get Info
CD3+CD8+ (T8 Suppressor) Cells per 100 cells, Blood

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.73
Last Updated
Version 2.73
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Células CD3+CD8+/100 células:Fracción numérica:Punto temporal:Celulas Mononucleares sanguíneas:Qn:
Synonyms: Cuantitativo
fr-FR French (France) CD3+CD8+/100 cellules:Fraction de nombres:Ponctuel:Cellules mononucléées de sang périphérique:Numérique:
it-IT Italian (Italy) Cellule.CD3+CD8+/100 cellule:NFr:Pt:Cellule mononucleate da sangue intero:Qn:
Synonyms: Cellule CD3 Cellule CD3+CD8+ Frazione numerica Microbiologia Punto nel tempo (episodio) Sangue
nl-NL Dutch (Netherlands) cellen.CD3+CD8+/100 cellen:getalsfractie:moment:mononucleaire cellen in bloed:kwantitatief:
tr-TR Turkish (Turkey) Hücreler.CD3+CD8+/100 hücre:SayFr:Zmlı:Kan MC:Kant:
Synonyms: Tam kandan mononükleer hücreler
zh-CN Chinese (China) 细胞.CD3+CD8+/100 个细胞:计数型分数:时间点:全血单个核细胞:定量型:
Synonyms: CD3+CD8+细胞 CD3细胞 Leu2 Leu-2 Leu4;Leu-4;T3 T8 T-8 Tsuppressor 全血(血液、血)单个核细胞(单核细胞、MC);全血标本(样品、样本、试样)单个核细胞 发现于 抑制性 T-细胞/细胞毒性 T-细胞、一些 NK 细胞之上。与一些成熟 T-细胞肿瘤和大颗粒淋巴细胞增多症相关 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 微生物学;微生物学试验;微生物学试验(培养、DNA、抗原及抗体) 抑制性 T 细胞 抑制性 T-细胞 数量型分数;数量或计数型分数;数量型分数或计数型分数 时刻;随机;随意;瞬间 细胞含量;细胞性;细胞性质;细胞构成;细胞类 经过门控分离的细胞 血;血液

Example Units

Unit Source
% Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=100857-2