101161-8

p-Fluorofentanyl/Creatinine [Mass Ratio] in Urine by Confirmatory method

Discouraged

Status Information

Status: DISCOURAGED
Comment: The Method values "Screen" and "Confirm" reflect a regulatory testing requirement rather than an actual laboratory method. This term has been discouraged in favor of terms specifying the true method (Immunoassay or Mass Spectrometry) or a methodless term where appropriate. Please select the replacement term that matches your actual testing method.

Part Descriptions

LP32035-5 Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Creatinine

LP411415-5 4-Fluorofentanyl
The compounds known as novel synthetic opioids (NSOs) have been emerging as drugs of abuse, given that many share pharmacological properties with common opioid agonists, yet they are difficult to detect and control. Since the early 2010s clandestine manufacturing of both novel fentanyl derivatives as well as other synthetic opioids has increased, with the list growing to upwards of more than 30 unique compounds. The list includes fentanyl analogs such as acetylfentanyl, butyrfentanyl, 4-methoxybutyrylfentanyl, 4-methylphenethylacetylfentanyl, furanylfentanyl, carfentanil (and its major metabolite norcarfentanil), ocfentanil, acrylfentanyl, 3-methylfentanyl and 4-fluorobutyrylfentanyl. Also, in the same category are non-fentanyl derived chemicals having opioid agonist activity such as AH-7921 and U47700(benzoamides) and MT-45 (a piperazine). The pharmacologic receptor profile of some predict that they would be highly addictive and in some cases much more potent (for example, 3-Methylfentanyl is about 1000 times and carfentanil may be 10,000 times more potent than morphine). The fact that they are often cut into heroin preparations or sold as counterfeit pain killers with users unaware of their content makes them particularly prone to overdose. The DEA has reported that the fentanyl crisis in the United States in the late 2010s has been largely fueled by NSOs PMID: 30634521. Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: 4-Fluorofentanyl/Creatinine:MRto:Pt:Urine:Qn:Confirm
Long Common Name: p-Fluorofentanyl/Creatinine [Mass Ratio] in Urine by Confirmatory method
Short Name: 4-Fluorofentanyl/Creat Ur Cfm
Display Name: 4-Fluorofentanyl/Creatinine Confirm (U) [Mass ratio]
Consumer Name Alpha Get Info: 4-Fluorofentanyl/Creatinine, Urine

Part Model Get Info

Component
4-Fluorofentanyl/Creatinine
LP434483-6
- Analyte
  4-Fluorofentanyl/Creatinine
  LP434483-6
  - Component Numerator
    4-Fluorofentanyl
    LP411415-5
    - Component Numerator Core
      4-Fluorofentanyl
      LP411415-5
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    Creatinine
    LP32035-5
    - Component Denominator Core
      Creatinine
      LP32035-5
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
MRto
LP6834-8
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Urine
LP7681-2
- System Core
  Urine
  LP7681-2
- Super System
  NULL
Scale
Qn
LP7753-9
Method
Confirm
LP6197-0

Basic Attributes

Class: DRUG/TOX
Type: Laboratory
First Released: Version 2.74
Last Updated: Version 2.83 (MIN)
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	4-fluorfentanyl/kreatinin:Hmotnostní poměr:Časový bod:Moč:Kvantitativní:Konfirmace
el-GR	Greek (Greece)	4-φθοροφεντανύλη/Κρεατινίνη:MRto:Pt:Ούρα:Qn:Επιβεβαίωση Synonyms: 4-φθοροφεντανύλη DRUG/TOX MRto Pt Qn Επιβεβαίωση Κρεατινίνη Ούρα
es-ES	Spanish (Spain)	4-fluorofentenilo/Creatinina:Relacion de Masa:Punto temporal:Orina:Qn:Confirmatorio Synonyms: Cuantitativo parafluorofentanilo
fr-FR	French (France)	4-fluorofentanyl/créatinine:Masse ratio:Ponctuel:Urine:Numérique:Confirmation
it-IT	Italian (Italy)	4-Fluorofentanyl/Creatinina:MRto:Pt:Urine:Qn:Conferma Synonyms: Livelli farmacologici e tossicologia Parafluorofentanil Punto nel tempo (episodio) Rapporto di Massa
pl-PL	Polish (Poland)	4-Fluorofentanyl/kreatynina:współczynnik masowy:punkt w czasie:mocz:ilościowy:potwierdzenie Synonyms: metoda potwierdzenia
zh-CN	Chinese (China)	4-氟芬太尼/肌酐:质量比率:时间点:尿液:定量型:毒理学确认试验 Synonyms: CR;Creat;肌氨酸酐;肌酸内酰胺;肌酸酐 UCr 可用数量表示的;定量性;数值型;数量型;连续数值型标尺尿;小便;下泉尿液肌酐尿液肌酸酐尿肌酸酐时刻;随机;随意;瞬间来自于同一体系的两种分析物的质量之比;质量比毒品毒品类确认方法;确认法;确认试验肌酸内酰胺药品类药物药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类药物类

Example Units

Unit	Source
ng/mL	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.