101318-4
17-Hydroxypregnenolone [Mass/volume] in Serum or Plasma --1 hour post dose corticotropin
Active
Part Descriptions
LP17184-0 17-Hydroxypregnenolone
17-Hydroxypregnenolone (also 17-OH-pregnenolone and 17-alpha-hydroxypregnenolone), is a C21 steroid that is obtained by hydroxylation of pregnenolone at the C17-alpha position. This step is performed by the mitochondrial cytochrome P450 enzyme 17-hydroxylase (CYP17A1) that is present in the adrenal and gonads. Peak levels are reached in humans at the end of puberty and then decline. High levels are also achieved during pregnancy.
Measurements of 17-OH-pregnenolone are useful in the diagnosis of certain forms of congenital adrenal hyperplasia. In patients with congenital adrenal hyperplasia due to 3 beta-hydroxysteroid dehydrogenase deficiency 17-OH-pregnenolone is increased, while in patients with congenital adrenal hyperplasia due to 17 alpha-hydroxylase deficiency levels are low to absent. Measurements of 17-OH-pregnenolone are useful in the diagnosis of certain forms of congenital adrenal hyperplasia. In patients with congenital adrenal hyperplasia due to 3 beta-hydroxysteroid dehydrogenase deficiency 17-OH-pregnenolone is increased, while in patients with congenital adrenal hyperplasia due to 17 alpha-hydroxylase deficiency levels are low to absent.
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Source: Wikipedia,
17-hydroxypregnenolone (Wikipedia)
LP17184-0 17-Hydroxypregnenolone
17-Hydroxypregnenolone, also known as 17-OH-PG, is a steroid hormone that is derived from cholesterol. 17-OH-PG is involved in the synthesis of cortisol, aldosterone and androstenedione in the adrenal glands. 17-OH-PG levels are measured to screen for congenital adrenal hyperplasia (CAH), a group of inherited disorders of the adrenal gland. High levels of 17-OH-PG in the blood indicate cortisol and aldosterone are not being produced in normal levels. PMID: 20077078
Source: Regenstrief LOINC
LOINC Names Get Info
- Fully-Specified Name
- 17-Hydroxypregnenolone^1H post dose corticotropin:
MCnc: Pt: Ser/Plas: Qn: - Long Common Name
- 17-Hydroxypregnenolone [Mass/volume] in Serum or Plasma --1 hour post dose corticotropin
- Short Name
- 17OH-Preg 1h p ACTH SerPl-mCnc
- Display Name
- 17-Hydroxypregnenolone 1 Hr post dose corticotropin [Mass/Vol]
- Consumer Name Alpha Get Info
- 17-Hydroxypregnenolone 1 hr after Corticotropin, Blood
Part Model Get Info
- Component
- 17-Hydroxypregnenolone^1H post dose corticotropin
LP434481-0
- Property
- MCnc
LP6827-2
- Time
- Pt
LP6960-1
- Time Core
- Pt
LP6960-1
- Time Modifier
- NULL
- System
- Ser/Plas
LP7576-4
- System Core
- Ser/Plas
LP7576-4
- Super System
- NULL
- Scale
- Qn
LP7753-9
- Method
- NULL
Basic Attributes
- Class
- CHAL
- Type
- Laboratory
- First Released
- Version 2.74
- Last Updated
- Version 2.75 (MIN)
- Order vs. Observation
- Observation
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 101314-3 | 17-Hydroxypregnenolone and 17-Hydroxyprogesterone p corticotropin stim panel - Serum or Plasma |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | 17-hydroxypregnenolon^1 hodina po dávce kortikotropinu: |
| el-GR | Greek (Greece) | 17-υδροξυπρογνενολόνη^1 ώρα μετά από δόση κορτικοτροπίνης: Synonyms: 1 ώρα κατόπιν δόσης 1 ώρα μετά από δόση κορτικοτροπίνης 17-υδροξυπρογνενολόνη CHAL MCnc Pt Qn κατόπιν δόσης Κορτικοτροπίνη μετά από δόση κορτικοτροπίνης Ορός Ορός/Πλάσμα Πλάσμα |
| es-ES | Spanish (Spain) | 17-Hidroxipregnenolona^1 hora pos dosis de corticotropina: Synonyms: Cuantitativo |
| fr-BE | French (Belgium) | 17-hydroxyprégnénolone^1 h post dose hormone adrénocorticotrope: Synonyms: 1h après dose ACTH ACTH Post dose. 1H |
| fr-FR | French (France) | 17-hydroxyprégnénolone^T01h après synacthène: |
| fr-CA | French (Canada) | 17-hydroxyprégnénolone^1 h post dose hormone adrénocorticotrope: |
| it-IT | Italian (Italy) | 17-Idrossipregnenolone^1h post dose corticotropina: Synonyms: 1 ora dopo dose 1 ora dopo stimolo con di corticotropina Concentrazione di Massa dopo dose dopo dose di corticotropina Plasma Punto nel tempo (episodio) Siero Siero o Plasma Test di provocazione |
| nl-NL | Dutch (Netherlands) | 17-hydroxypregnenolon^60 min na dosis corticotropin: Synonyms: 1 uur na dosis 1 uur na dosis corticotropin adrenocorticotroop hormoon; |
| pl-PL | Polish (Poland) | 17-Hydroksypregnenolon^1h po 250 ug kortykotropiny: Synonyms: 1 godzina po podaniu 250 ug ACTH 1 godzina po podaniu dawki ACTH Hormon adrenokortykotropowy po podaniu dawki po podaniu dawki kortykotropiny; |
| ru-RU | Russian (Russian Federation) | 17-Гидроксипрегненолон^1 час после дозы кортикотропина: Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
| tr-TR | Turkish (Turkey) | 17-Hidroksipregnenolon^1Sa snr kortikotropin dozu: |
| zh-CN | Chinese (China) | 17-羟基孕烯醇酮^在给予剂量促肾上腺皮质激素之后1小时: Synonyms: 17-Alpha-羟基娠烯醇酮; |
Example Units
| Unit | Source |
|---|---|
| ng/dL | Example UCUM Units |
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LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://