101484-4
Ceftolozane+Tazobactam [Susceptibility] by MIC.VOC detection in Positive blood culture
Active
Part Descriptions
LP172561-5 Ceftolozane+Tazobactam
Ceftolozane/tazobactam is a first-line IV therapy for the treatment of certain serious Gram-negative bacterial infections, including those caused by multi-drug resistant Pseudomonas aeruginosa.
Source: Regenstrief LOINC
LP172561-5 Ceftolozane+Tazobactam
Ceftolozane is a cephalosporin with powerful activity against Gram-negative bacteria including Pseudomonas aeruginosa and Enterobacteriaceae.[http://aac.asm.org/content/57/4/1577.full] Tazobactam is a beta lactamase inhibitor and penicillin derivative that is effective against beta-lactamase-producing bacteria.[PubChem: 123630] Ceftolozane blocks penicillin binding proteins which disrupts bacterial cell-wall synthesis that leads to bacterial cell death. When tazobactam is added to ceftolozane, there is a broader spectrum of antimicrobial activity against resistant strains including extended spectrum beta-lactamases (ESBLs).Tazobactam prevents class A beta-lactamases and some class C beta-lactamases from hydrolyzing ceftolozane. Together, ceftolozane+tazobactam are an effective treatment for complicated urinary tract infections, complicated intra-abdominal infections, hospital-acquired bacterial pneumonia, and ventilator-associated bacterial pneumonia. PMID: 25516692
Source: Regenstrief LOINC
LP434420-8 MIC.VOC detection
MIC.VOC detects bacterial growth using an array of chemical small molecule sensors that change color in the presence of various metabolic gases (volatile organic compounds) emitted by growing bacteria during incubation to determine minimum inhibitory concentrations (MIC).
Source: bioMerieux
Fully-Specified Name
- Component
- Ceftolozane+Tazobactam
- Property
- Susc
- Time
- Pt
- System
- Bld.pos growth
- Scale
- OrdQn
- Method
- MIC.VOC detection
Additional Names
- Short Name
- Ceftolozane+Tazobactam BldPos MICVOC det
- Display Name
- Ceftolozane+Tazobactam MIC.VOC detection (Pos bld culture) [Susc]
- Consumer Name Alpha Get Info
- Susceptibility to Ceftolozane+Tazobactam
Basic Attributes
- Class
- ABXBACT
- Type
- Laboratory
- First Released
- Version 2.74
- Last Updated
- Version 2.75
- Order vs. Observation
- Observation
Member of these Panels
LOINC | Long Common Name |
---|---|
101505-6 | Bacterial susceptibility panel by Minimum inhibitory concentration VOC detection |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Ceftolozane+Tazobactam: |
fr-FR | French (France) | Ceftolozane+tazobactam: |
it-IT | Italian (Italy) | Ceftolozane+Tazobactam: Synonyms: Concentrazione minima inibitoria Punto nel tempo (episodio) Rilevamento microfono vocale Sangue Sensibilità (microrganismi) Suscettibilità agli antibiotici |
zh-CN | Chinese (China) | 头孢洛林+他唑巴坦: Synonyms: 3a-甲基-7-氧代-3b-(1H-1,2,3,-三唑-1-亚甲基)-4-硫杂-1-氮杂双环[3.2.0]庚烷-2a-羧酸4, |
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