Version 2.77

Part Descriptions

LP15747-6   Gentamicin
Gentamicin is an aminoglycoside antibiotic, which has a bactericidal mode of action binding to the ribosome and various ribozymes to inhibit protein synthesis. Gentamicin is a hydrophilic molecule and is considered to have limited capacity to penetrate eukaryotic cells. Administered intravenously or intramuscularly, gentamicin is used to treat many bacterial infections, particularly gram-negative organisms such as meningitis, and infections of the blood, abdomen, lungs, skin, bones, joints and urinary tract, and is often used to treat severe cases of tularemia and the plague. The effect of gentamicin is mediated through the production of reactive oxygen species (ROS), which causes destablization of iron-sulfur (Fe-S) clusters and generates toxic, bactericidal compounds through the Fenton reaction. Gentamicin may cause kidney, nerve and severe hearing problems. More common side effects include nausea, headache, fever, rash and hoarseness. PMID: 26503658 [MedlinePlus Drug:a682275] Source: Regenstrief LOINC

LP434420-8   MIC.VOC detection
MIC.VOC detects bacterial growth using an array of chemical small molecule sensors that change color in the presence of various metabolic gases (volatile organic compounds) emitted by growing bacteria during incubation to determine minimum inhibitory concentrations (MIC). Source: bioMerieux

Fully-Specified Name

Component
Gentamicin
Property
Susc
Time
Pt
System
Bld.pos growth
Scale
OrdQn
Method
MIC.VOC detection

Additional Names

Short Name
Gentamicin Bld Pos MIC.VOC det
Display Name
Gentamicin MIC.VOC detection (Pos bld culture) [Susc]
Consumer Name Alpha Get Info
Susceptibility to Gentamicin

Basic Attributes

Class
ABXBACT
Type
Laboratory
First Released
Version 2.74
Last Updated
Version 2.75
Order vs. Observation
Observation

Member of these Panels

LOINC Long Common Name
101505-6 Bacterial susceptibility panel by Minimum inhibitory concentration VOC detection

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Gentamicin:Empfindlichkeit (Mikroorganismen):Zeitpunkt:Blut.positives Wachstum:Ordinal oder Quantitativ:Minimale Hemmstoffkonzentration.flüchtige organische Verbindungen
es-ES Spanish (Spain) Gentamicina:Susceptibilidad:Punto temporal:Sangre crecimiento positivo:Ordinal Cuantitativo:Detección de MIC.VOC
fr-FR French (France) Gentamicine:Sensibilité:Ponctuel:Hémoculture positive:Alphanumérique:CMI détection VOC
it-IT Italian (Italy) Gentamicina:Susc:Pt:Emocolture positive:OrdQn:Rilevamento MIC.VOC
Synonyms: Concentrazione minima inibitoria Punto nel tempo (episodio) Rilevamento microfono vocale Sangue Sensibilità (microrganismi) Suscettibilità agli antibiotici
zh-CN Chinese (China) 庆大霉素:抗生素敏感性:时间点:血液.生长阳性:定量型或序数型:最小抑菌浓度法.挥发性有机化合物检测
Synonyms: MIC（最低抑制浓度、最低抑制浓度法、最低抑菌浓度、最低抑菌浓度法、最小抑制浓度、最小抑制浓度法、最小抑菌浓度、Minimum Inhibitory Concentration）.挥发性有机化合物（volatile organic compound、VOC）检测（测定）; 抗生素敏感性(微生物);敏感性;某种抗微生物制剂对于某个分离株的影响;药物敏感性;药物敏感性(微生物) 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类 时刻;随机;随意;瞬间 最低抑制浓度;最低抑制浓度法;最低抑菌浓度;最低抑菌浓度法;最小抑制浓度;最小抑制浓度法;最小抑菌浓度;Minimum Inhibitory Concentration;MIC 正泰霉素;艮他霉素 血;血液 血液.阳性生长;血培养阳性;阳性血培养;阳性血液培养;全血.生长阳性

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=101494-3