101815-9

Cytomegalovirus DNA [Units/volume] (viral load) in Cerebrospinal Fluid by NAA with probe detection

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Part Description

LP14255-1 Cytomegalovirus
Cytomegalovirus is a member of the family Herpesviridae and also known as Human Herpesvirus-5 (HHV-5). It contains a linear double-stranded DNA encased in an icosahedral capsid that is surrounded by a viral envelope. It replicates slowly and may take weeks for the infection to become visible microscopically. Its life cycle includes a lytic and a latent phase. During the lytic phase the cytoskeleton of the infected cell is disrupted and becomes very large. The enlarged cell eludes detection by natural killer (NK) cells by encoding UL16. UL16 is a protein that binds to the ligand NDG2D which is a surface receptor on NK cells and, when blocked, prevents the CMV infected cell from apoptotic signaling to NK cells to destroy it.https://pedclerk.bsd.uchicago.edu/page/cytomegalovirus-cmv In the US one in three children are infected by CMV by the age of five and over half of adults are infected by age 40. Infection with CMV is mostly asymptomatic. Symptoms when present include fever, sore throat, fatigue, swollen glands. CMV can occasionally lead to mononucleosis or hepatitis. Immunocompromised patients experience much more acute symptoms that can affect the eyes, lungs, liver, esophagus, stomach, and intestines. For babies born with CMV, involvement with the brain, spleen, lung, liver can occur. In addition, there may be growth problems and hearing loss which is the most common symptom in congenital CMV infection. CMV is transmitted in urine, saliva, blood, tears, semen and breast milk by direct contact. Normally no treatment is necessary, but for severe cases medication is available.https://www.cdc.gov/cmv/overview.html Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Cytomegalovirus DNA:ACnc:Pt:CSF:Qn:Probe.amp.tar
Long Common Name: Cytomegalovirus DNA [Units/volume] (viral load) in Cerebrospinal Fluid by NAA with probe detection
Short Name: CMV DNA CSF NAA+probe-aCnc
Display Name: CMV DNA NAA+probe Qn (CSF)
Consumer Name Alpha Get Info: Cytomegalovirus (CMV), Spinal fluid

Part Model Get Info

Component
Cytomegalovirus DNA
LP37883-3
- Analyte
  Cytomegalovirus DNA
  LP37883-3
  - Component Numerator
    Cytomegalovirus DNA
    LP37883-3
    - Component Numerator Core
      Cytomegalovirus
      LP14255-1
    - Component Numerator Core Suffix
      DNA
      LP32416-7
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
ACnc
LP6773-8
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
CSF
LP7156-5
- System Core
  CSF
  LP7156-5
- Super System
  NULL
Scale
Qn
LP7753-9
Method
Probe.amp.tar
LP6464-4

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.75
Last Updated: Version 2.83 (MIN)
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Cytomegalovirus DNA:Arbitrární koncentrace:Časový bod:Mozkomíšní mok:Kvantitativní:Amplifikace nukleových kyselin s detekcí sondou
el-GR	Greek (Greece)	Κυτταρομεγαλοϊός DNA:ACnc:Pt:ΕΝΥ:Qn:Ανιχνευτής.ενίσχυση.στόχου Synonyms: ACnc DNA MICRO Pt Qn Ανιχνευτής Ανιχνευτής.ενίσχυση Ανιχνευτής.ενίσχυση.στόχου ΕΝΥ Κυτταρομεγαλοϊός
es-ES	Spanish (Spain)	Citomegalovirus ADN:Concentración arbitraria:Punto temporal:Líquido Cefalorraquideo:Qn:Sonda con amplificación dirigida Synonyms: Cuantitativo
fr-BE	French (Belgium)	Cytomégalovirus ADN:Concentration arbitraire:Temps ponctuel:LCR:Quantitatif:Sonde avec amplification de la cible Synonyms: CMV
fr-FR	French (France)	Cytomégalovirus ADN:Arbitraire/Volume:Ponctuel:Liquide céphalorachidien:Numérique:PCR amplification de cible
fr-CA	French (Canada)	Cytomégalovirus, ADN:Concentration arbitraire:Temps ponctuel:LCR:Quantitatif:Sonde avec amplification de la cible
it-IT	Italian (Italy)	Citomegalovirus DNA:ACnc:Pt:LCS:Qn:Sonda.amp.tar Synonyms: Concentrazione Arbitraria Liquido cerebrospinale Microbiologia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
nl-NL	Dutch (Netherlands)	Cytomegalovirus DNA:eenheid/volume:moment:liquor cerebrospinalis:kwantitatief:probe-detectie Synonyms: probe.amp.tar
pl-PL	Polish (Poland)	Wirus cytomegalii DNA:stężenie w jednostkach umownych:punkt w czasie:płyn mózgowo-rdzeniowy:ilościowy:sonda.amplifikacja.cel Synonyms: amplifikacja kwasu nukleinowego z detekcją za pomocą sondy amplifikacja z detekcją za pomocą sondy Cytomegalowirus DNA Cytomeglaowirusa Kwas deoksyrybonukleinowy
ru-RU	Russian (Russian Federation)	Цитомегаловирус ДНК:ПроизвКонц:ТчкВрм:ЦСЖ:Колич:Проба.усил.миш Synonyms: ДНК проба;ДНК зонд Количественный Проба с мишени усилением Произвольная концентрация Точка во времени;Момент Цереброспинальная жидкость
tr-TR	Turkish (Turkey)	Cytomegalovirus DNA:SçKons:Zmlı:BOS:Kant:Prob.amf.hdf
zh-CN	Chinese (China)	巨细胞病毒 DNA:任意型浓度:时间点:脑脊液:定量型:探针法.基因扩增.靶向 Synonyms: CMV DNA CMV;涎腺病毒;细胞巨化病毒;细胞肥大病毒 CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液任意型浓度(单位体积);任意浓度;单位体积的任意单位数;人工型浓度借助扩增的探针方法;借助扩增的探针法;探针法.扩增借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向去氧核糖核酸;脱氧核糖核酸去氧核糖核酸;脱氧核糖核酸;脱氧核糖核酸（Deoxyribonucleic acid，DNA）可用数量表示的;定量性;数值型;数量型;连续数值型标尺微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）扩增型扩增性探针靶向扩增定量型任意浓度时刻;随机;随意;瞬间病毒载量经过扩增的脊液脊髓液脑脊液（Cerebral spinal fluid，CSF）脑脊髓液脱氧核糖核酸探针

Example Units

Unit	Source
[IU]/mL	Example UCUM Units

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

CodeSystem lookup: https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=101815-9

LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.