101903-3

K Ag [Presence] on Red Blood Cells from Fetus

Active

Part Description

LP14926-7 K
Kell is highly polymorphic. It has two major codominant alleles, k and K, which result from a SNP (698C→T), and the corresponding k and K antigens differ by a single amino acid change (T193M). Mostly IgG antibodies, so IgM is uncommon. Anti-K does not bind complement. If hemolysis does occur, it is extravascular in nature. Anti-K can cause a severe hemolytic transfusion reaction and severe fetal anemia. In the RBC membrane, the Kell glycoprotein is covalently linked to the XK protein, a multipass membrane protein thought to have a role in transport. In the absence of XK, a condition called McLeod syndrome, Kell antigens are only weakly expressed and the RBCs are abnormal with spiky projections (acanthocytosis). Systemic findings include muscular dystrophy, cardiomyopathy, psychiatric disturbances, and neurological defects, such as loss of reflexes and movement disorders. The frequency of K antigens is 2% in Blacks, 9% in Caucasians, up to 25% in Arabs populations. Beck L, Blood groups and red cell antigens. NCBI Bookself [Internet Book], 2005. Source: National Library of Medicine, K

LOINC Names Get Info

Fully-Specified Name: K Ag:PrThr:Pt:RBC^Fetus:Ord:
Long Common Name: K Ag [Presence] on Red Blood Cells from Fetus
Short Name: K Ag RBC Fetus Ql
Display Name: K Ag Ql (RBC fetus)
Consumer Name Alpha Get Info: Fetal K antigen

Part Model Get Info

Component
K Ag
LP38753-7
- Analyte
  K Ag
  LP38753-7
  - Component Numerator
    K Ag
    LP38753-7
    - Component Numerator Core
      K
      LP14926-7
    - Component Numerator Core Suffix
      Ag
      LP20666-1
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
PrThr
LP217195-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
RBC^Fetus
LP281826-0
- System Core
  RBC
  LP7536-8
- Super System
  Fetus
  LP6982-5
Scale
Ord
LP7751-3
Method
NULL

Basic Attributes

Class: BLDBK
Type: Laboratory
First Released: Version 2.75
Last Updated: Version 2.76 (MIN)
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	K Ag:Přítomnost nebo práh:Časový bod:Erytrocyty^Plod:Ordinální:
el-GR	Greek (Greece)	K Αντιγόνο:PrThr:Pt:Ερυθρά αιμοσφαίρια^Έμβρυο:Ord: Synonyms: BLDBK K Ord PrThr Pt Αντιγόνο Έμβρυο Ερυθρά αιμοσφαίρια
es-ES	Spanish (Spain)	K Antígeno:PrThr:Punto temporal:Glóbulos rojos^Feto:Ord:
et-EE	Estonian (Estonia)	K antigeen:PrThr:Pt:RBC^loode:Ord: Synonyms: Erütrotsüüdid Järgarvuline Juhuslik
fr-BE	French (Belgium)	K Ag:PrThr:Temps ponctuel:GR^Foetus:Ordinal: Synonyms: Antigène
fr-CA	French (Canada)	K, Ag:Présence-Seuil:Temps ponctuel:GR^Foetus:Ordinal:
fr-FR	French (France)	KEL1 (K) Ag:Présence/Seuil:Ponctuel:Érythrocytes^foetus:Qualitatif:
it-IT	Italian (Italy)	K, Ag:PrThr:Pt:RBC^feto:Ord: Synonyms: Banca del sangue Globuli rossi Presenza o Soglia Punto nel tempo (episodio) RBC^Feto
nl-NL	Dutch (Netherlands)	K Ag:aanwezigheid:moment:erytrocyten^foetus:ordinaal: Synonyms: antigeen rode bloedcellen
ru-RU	Russian (Russian Federation)	K Аг:PrThr:ТчкВрм:Эритроциты^Плод:Пор: Synonyms: Порядковый Точка во времени;Момент
tr-TR	Turkish (Turkey)	K Ag:MevcEşik:Zmlı:Eritrosit^Fetus:Srl: Synonyms: Antijen Mevcut RBC
zh-CN	Chinese (China)	K 抗原:存在情况或阈值:时间点:红细胞^胎儿:序数型: Synonyms: Ag K 型 K 抗原 RBC;RBCS;红血球;红血细胞;赤血球依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）时刻;随机;随意;瞬间红细胞（RBC）^胎儿（胚胎、胎）胎;超系统 - 胎儿血库;血库检验;血库检验类;血库检验项目;血库检验项目类;血库类;血库试验;血库试验项目;血库试验项目类

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