Version 2.78

Part Description

LP14255-1   Cytomegalovirus
Cytomegalovirus is a member of the family Herpesviridae and also known as Human Herpesvirus-5 (HHV-5). It contains a linear double-stranded DNA encased in an icosahedral capsid that is surrounded by a viral envelope. It replicates slowly and may take weeks for the infection to become visible microscopically. Its life cycle includes a lytic and a latent phase. During the lytic phase the cytoskeleton of the infected cell is disrupted and becomes very large. The enlarged cell eludes detection by natural killer (NK) cells by encoding UL16. UL16 is a protein that binds to the ligand NDG2D which is a surface receptor on NK cells and, when blocked, prevents the CMV infected cell from apoptotic signaling to NK cells to destroy it.[https://pedclerk.bsd.uchicago.edu/page/cytomegalovirus-cmv] In the US one in three children are infected by CMV by the age of five and over half of adults are infected by age 40. Infection with CMV is mostly asymptomatic. Symptoms when present include fever, sore throat, fatigue, swollen glands. CMV can occasionally lead to mononucleosis or hepatitis. Immunocompromised patients experience much more acute symptoms that can affect the eyes, lungs, liver, esophagus, stomach, and intestines. For babies born with CMV, involvement with the brain, spleen, lung, liver can occur. In addition, there may be growth problems and hearing loss which is the most common symptom in congenital CMV infection. CMV is transmitted in urine, saliva, blood, tears, semen and breast milk by direct contact. Normally no treatment is necessary, but for severe cases medication is available.[https://www.cdc.gov/cmv/overview.html] Source: Regenstrief LOINC

Fully-Specified Name

Component
Cytomegalovirus DNA
Property
PrThr
Time
Pt
System
Respiratory System Specimen
Scale
Ord
Method
Probe.amp.tar

Additional Names

Short Name
CMV DNA Resp Ql NAA+probe
Display Name
CMV DNA NAA+probe Ql (Respiratory system specimen)
Consumer Name Alpha Get Info
Cytomegalovirus (CMV), Respiratory system specimen

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.75
Last Updated
Version 2.77
Change Reason
Release 2.77: SYSTEM: Updated to the new value Respiratory System Specimen from Respiratory.;
Order vs. Observation
Both

Member of these Groups Get Info

LOINC Group Group Name
LG34031-1 Cytomegalovirus DNA|PrThr|Sys:ANYResp

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Citomegalovirus ADN:PrThr:Punto temporal:Muestra del sistema respiratorio:Ord:Sonda con amplificación dirigida
Synonyms: Muestra del tracto respiratorio Muestra respiratoria Tracto respiratorio
fr-FR French (France) Cytomégalovirus ADN:Présence/Seuil:Ponctuel:Respiratoire:Qualitatif:PCR amplification de cible
fr-CA French (Canada) Cytomégalovirus, ADN:Présence-Seuil:Temps ponctuel:Échantillon du système respiratoire:Ordinal:Sonde avec amplification de la cible
it-IT Italian (Italy) Citomegalovirus DNA:PrThr:Pt:Campione da Sistema Respiratorio:Ord:Sonda.amp.tar
Synonyms: Campione da Apparato Respiratorio Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
nl-NL Dutch (Netherlands) Cytomegalovirus DNA:aanwezigheid:moment:respiratoir monster:ordinaal:probe-detectie
Synonyms: probe.amp.tar systema respiratorium; ademhalingsstelsel
zh-CN Chinese (China) 巨细胞病毒 DNA:存在情况或阈值:时间点:呼吸系统标本:序数型:探针法.基因扩增.靶向
Synonyms: CMV DNA CMV;涎腺病毒;细胞巨化病毒;细胞肥大病毒 供检查用的材料;待检物;待试验物;样品;样本;试料;试样 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向 去氧核糖核酸;脱氧核糖核酸 去氧核糖核酸;脱氧核糖核酸;脱氧核糖核酸（Deoxyribonucleic acid，DNA） 受检物 呼吸道标本（样品、样本）;呼吸系统标本（样品、样本） 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 扩增型 扩增性 时刻;随机;随意;瞬间 样品 样本 经过扩增的 脱氧核糖核酸探针 试样

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=101947-0