102085-8
CNS Demyelinating Disease Panel - Serum or Plasma by Flow cytometry (FC)
Active
69048-7 Immunologist review of results
Fully-Specified Name
- Component
- Immunologist review
- Property
- Imp
- Time
- Pt
- System
- XXX
- Scale
- Nar
- Method
Additional Names
- Short Name
- Immunologist review
- Display Name
- Immunologist review [Interp]
- Consumer Name Alpha Get Info
- Immunologist review of test result
Basic Attributes
- Class
- MISC
- Type
- Laboratory
- First Released
- Version 2.38
- Last Updated
- Version 2.75
- Change Reason
- Release 2.75: ORDER_OBS: submitter requested change;
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 4075
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 96451-0 | Alpha-1-Fetoprotein and Alpha-1-Fetoprotein.L3 panel - Serum or Plasma |
| 90414-4 | B-cell phenotyping panel - Blood |
| 103575-7 | Cat epithelium IgE panel - Serum or Plasma |
| 102085-8 | CNS Demyelinating Disease Panel - Serum or Plasma by Flow cytometry (FC) |
| 104134-2 | Dementia evaluation panel - Cerebral spinal fluid |
| 104595-4 | Dengue virus Ab.IgG and IgM and NS1 Ag panel - Serum or Plasma |
| 104673-9 | Diabetes mellitus type 1 autoimmune panel - Serum or Plasma |
| 103574-0 | Dog dander IgE panel - Serum or Plasma |
| 96452-8 | Hepatocellular carcinoma risk panel - Serum or Plasma |
| 90416-9 | Lymphocyte subset and B-cell phenotyping panel - Blood |
| 101416-6 | Pediatric autoimmune central nervous system disorders evaluation panel - Cerebral spinal fluid |
| 101417-4 | Pediatric autoimmune central nervous system disorders evaluation panel - Serum or Plasma |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-AT | German (Austria) | Synonyms: Komm.Auto.AK |
| es-MX | Spanish (Mexico) | Revisión de inmunólogo: |
| es-ES | Spanish (Spain) | Revisión del inmunólogo: |
| fr-FR | French (France) | Validation des résultats d'immunologie: |
| it-IT | Italian (Italy) | Immunologo, esame: Synonyms: Esame di immunologo Impressione/interpretazione di studio Miscellanea Punto nel tempo (episodio) |
| nl-NL | Dutch (Netherlands) | beoordeling door immunoloog: |
| ru-RU | Russian (Russian Federation) | Иммунолог рецензия: Synonyms: Впечатление/интерпретация исследования Описательный Точка во времени; |
| tr-TR | Turkish (Turkey) | İmmünolog değerlendirmesi: |
| zh-CN | Chinese (China) | 免疫学家审核: Synonyms: 不明的; |
90248-6 Myelin oligodendrocyte glycoprotein IgG1 Ab [Presence] in Serum or Plasma by Flow cytometry (FC)
Part Descriptions
LP268267-4 Myelin oligodendrocyte glycoprotein Ab.IgG1
Myelin oligodendrocyte glycoprotein (MOG) is a protein made up of two polypeptides with molecular masses of 26 and 28 kilodaltons, respectively. MOG is located on the surface of myelin and oligodendrocyte cytoplasmic membranes and binds to the monoclonal antibody 8-18C5. PMID: 1373175 MOG is a probable autoantigen target associated with multiple sclerosis (MS) and other demyelinating diseases (DD) of the central nervous system. PMID: 1373175 That being said, there is variation in the level of MOG antibody found in patients with MS and DD with inconsistencies between MOG antibody measurements using western blot and ELISA test methods, making it a questionable biomarker for DD. PMID: 17294606 MOG IgG1 is the most prevalent isotype of IgG in patients with DD. PMID: 29063242
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Myelin oligodendrocyte glycoprotein Ab.IgG1
- Property
- PrThr
- Time
- Pt
- System
- Ser/Plas
- Scale
- Ord
- Method
- Flow cytometry
Additional Names
- Short Name
- MOG IgG1 SerPl Ql FC
- Display Name
- Myelin oligodendrocyte glycoprotein IgG1 Ab FC Ql
- Consumer Name Alpha Get Info
- Myelin oligodendrocyte glycoprotein IgG1 antibody, Blood
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.65
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 5924
Example Answer List LL360-9
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
| Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 |
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 102085-8 | CNS Demyelinating Disease Panel - Serum or Plasma by Flow cytometry (FC) |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-MX | Spanish (Mexico) | Glicoproteína de oligodendrocitos de mielina Ab.IgG1: |
| es-ES | Spanish (Spain) | Mielina de oligodendrocitos glicoproteína Inmunoglobulina G1: |
| fr-FR | French (France) | MOG anticorps IgG1: |
| it-IT | Italian (Italy) | Glicoproteina oligodendrocita mielinica Ab.IgG1: Synonyms: Anticorpi IgG1 anticorpo Citometria a flusso (FC) MOG Plasma Presenza o Soglia Punto nel tempo (episodio) Siero Siero o Plasma Sierologia (anticorpi e la maggior parte degli ant |
| nl-NL | Dutch (Netherlands) | myeline-oligodendrocyt-glycoproteïne As.IgG1: Synonyms: antistof; |
| pl-PL | Polish (Poland) | Glikoproteina mieliny oligodendrocytów Ab.IgG1: Synonyms: Glikoproteina mieliny oligodendrocytów Przeciwciała do glikoproteiny mieliny oligodendrocytów Przeciwciała IgG1 do MOG |
| zh-CN | Chinese (China) | 髓鞘少突胶质细胞糖蛋白 抗体.IgG1: Synonyms: Ab.IgG1; |
Third Party Copyright
This material includes SNOMED Clinical Terms® (SNOMED CT®) which is used by permission of the International Health Terminology Standards Development Organisation (IHTSDO) under license. All rights reserved. SNOMED CT® was originally created by The College of American Pathologists. "SNOMED" and "SNOMED CT" are registered trademarks of the IHTSDO.
This material includes content from the US Edition to SNOMED CT, which is developed and maintained by the U.S. National Library of Medicine and is available to authorized UMLS Metathesaurus Licensees from the UTS Downloads site at https://uts.nlm.nih.gov.
Use of SNOMED CT content is subject to the terms and conditions set forth in the SNOMED CT Affiliate License Agreement. It is the responsibility of those implementing this product to ensure they are appropriately licensed and for more information on the license, including how to register as an Affiliate Licensee, please refer to http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org<mailto:info@snomed.org>. This may incur a fee in SNOMED International non-Member countries.
43638-6 Aquaporin 4 water channel IgG Ab [Presence] in Serum or Plasma
Part Descriptions
LP39188-5 Aquaporin 4 water channel Ab.IgG
The water channel aquaporin 4 (AQP4) receptor regulates the water homeostasis in the central nervous system (CNS). Autoantibodies to the AQP4 receptor bind to the receptor and cause neuromyelitis optica (NMO) which is an idiopathic, severe, demyelinating disease of the CNS that primarily affects the optic nerve and spinal cord. Before the discovery of the AQP4 receptor antibody NMO was often misdiagnosed as a variant of multiple sclerosis (MS). With improved clinical laboratory tests and distinct immunological and pathological attributes the two diseases are less often confused. Distinguishing MS and NMO is especially important because they have different treatments. Treatment for NMO includes corticosteroids and plasmapheresis; typical medications used to treat MS, such as beta-interferon and glatiramer acetate are not effective against NMO. During the disease process, the aquaporin 4 receptor antibody binds to the aquaporin 4 receptor initiating the activation of complement, inflammatory demyelination and necrosis. Eighty to ninety percent of patients with NMO experience recurrent episodes of optic neuritis and myelitis. Many patients with NMO also have other autoimmune diseases including thyroiditis, systemic lupus erythematosus
and Sjogren's syndrome. PMID: 17706564 Detection of APQ4-IgG is indicative of a relapsing disease. Immediate treatment with immunosuppressive drugs reduces the frequency and disability of future attacks. [http://labmed.ucsf.edu/labmanual/db/dataall/tests/1424.html]
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Aquaporin 4 water channel Ab.IgG
- Property
- PrThr
- Time
- Pt
- System
- Ser/Plas
- Scale
- Ord
- Method
Additional Names
- Short Name
- AQP4 H2O channel IgG SerPl Ql
- Display Name
- Aquaporin 4 water channel IgG Ql
- Consumer Name Alpha Get Info
- Aquaporin 4 water channel IgG antibody, Blood
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.17
- Last Updated
- Version 2.73
- Change Reason
- Release 2.67: COMPONENT: Updated "receptor" to "water channel" per current scientific nomenclature; Previous Releases: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 5066
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 102085-8 | CNS Demyelinating Disease Panel - Serum or Plasma by Flow cytometry (FC) |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG17408-2 | Aquaporin 4 water channel Ab.IgG| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Receptor de Acuaporina 4 IgG: |
| es-MX | Spanish (Mexico) | Acuaporina 4 canal de agua Ab.IgG: |
| et-EE | Estonian (Estonia) | Akvaporiin 4 retseptor antikehad.IgG: Synonyms: Immuunglobuliin G Järgarvuline Juhuslik Plasma Seerum Seerum või plasma |
| fr-CA | French (Canada) | Récepteur Aquaporin 4, IgG: |
| fr-BE | French (Belgium) | Récepteur Aquaporin 4 Anticorps. IgG: Synonyms: Anticorps |
| fr-FR | French (France) | Aquaporine 4 récepteur anticorps IgG: |
| it-IT | Italian (Italy) | Acquaporina 4, canale idrico Ab.IgG: Synonyms: anticorpi IgG anticorpo Canale idrico dell''acquaporina 4 Plasma Presenza o Soglia Punto nel tempo (episodio) Siero Siero o Plasma Sierologia (anticorpi e la maggior parte degli ant |
| nl-NL | Dutch (Netherlands) | aquaporine 4 waterkanaal As.IgG: Synonyms: antistof; |
| pt-BR | Portuguese (Brazil) | Neuromyelitis optica Ac.IgG: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Аквапорина 4 рецепторы Ат.IgG: Synonyms: Антитело Плазма Порядковый Сыворотка Сыворотка или Плазма Точка во времени; |
| tr-TR | Turkish (Turkey) | Akuaporin 4 reseptörü Ab.IgG: Synonyms: Ak Ak.IgG Mevcut |
| uk-UA | Ukrainian (Ukraine) | Аквапорин-4 водний канал Антитіла. IgG: Synonyms: ABS; |
| zh-CN | Chinese (China) | 水通道蛋白 4 受体 抗体.IgG: Synonyms: Ab.IgG; |