LOINC
Version 2.69

10461-2Alpha-1-Antichymotrypsin Ag [Presence] in Tissue by Immune stainActive

Part Description

LP14642-0   Alpha-1-Antichymotrypsin
Alpha 1-antichymotrypsin is an alpha globulin glycoprotein that is a member of the serpin superfamily.

It inhibits the activity of certain enzymes called proteases, such as cathepsin G that is found in neutrophils, and chymases found in mast cells, by cleaving them into a different shape or conformation. This activity protects some tissues, such as the lower respiratory tract, from damage caused by proteolytic enzymes.

This protein is produced in the liver, and is an acute phase protein that is induced during inflammation. Deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease.

Alpha 1-antichymotrypsin is also associated with the pathogenesis of Alzheimer's disease as it enhances the formation of amyloid-fibrils in this disease Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

Fully-Specified Name

Component
Alpha-1-Antichymotrypsin Ag
Property
PrThr
Time
Pt
System
Tiss
Scale
Ord
Method
Immune stain

Additional Names

Short Name
A1ACT Ag Tiss Ql ImStn
Display Name
Alpha-1-Antichymotrypsin Ag Immune stain Ql (Tiss)
Consumer Name Alpha
Alpha-1-Antichymotrypsin antigen, Tissue

Basic Attributes

Class
PATH
Type
Laboratory
First Released
Version 1.0i
Last Updated
Version 2.56
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Language Variants Get Info

zh-CNChinese (China)
Alpha-1-抗凝乳蛋白酶 抗原:存在情况或阈值:时间点:组织与涂片:序数型:免疫染色法
nl-NLDutch (Netherlands)
alfa-1-antichymotrypsine Ag:aanwezigheid:moment:weefsel en uitstrijkjes:ordinaal:immunokleuring
et-EEEstonian (Estonia)
Alfa-1-antikümotrüpsiin antigeen:PrThr:Pt:Tis:Ord:Immuunvärv
fr-BEFrench (Belgium)
Alpha-1-antichymotrypsine Ag:PrThr:Temps ponctuel:Tissu:Ordinal:Coloration immunologique
fr-CAFrench (Canada)
Alpha-1-antichymotrypsine , Ag:Présence-Seuil:Temps ponctuel:Tissu:Ordinal:Coloration immunologique
fr-FRFrench (France)
Alpha-1 antichymotrypsine antigène:Présence/Seuil:Ponctuel:Tissu:Qualitatif:Coloration immune
it-ITItalian (Italy)
Alfa-1-Antichimotripsina , Ag:PrThr:Pt:Tessuto:Ord:Colorazione immunologica
ko-KRKorean (Korea, Republic of)
알파-1-안티키모트립신 항원:임의농도:검사시점:조직:순위척도:면역염색
pt-BRPortuguese (Brazil)
Alfa-1-Antiquimotripsina Ag:ACnc:Pt:Tecido:Ord:Imunocoloração
ru-RURussian (Russian Federation)
Альфа-1-Антихимотрипсин Аг:PrThr:ТчкВрм:Тк:Пор:Иммуногистохимическая окраска
es-ARSpanish (Argentina)
antígeno de alfa-1-antiquimotripsina:concentración arbitraria:punto en el tiempo:tejido, no especificado:ordinal:tinción inmunológica
es-ESSpanish (Spain)
Alfa-1-Antiquimotripsina Antígeno:PrThr:Punto temporal:Tejido:Ord:Tinción de inmunohistoquímica
tr-TRTurkish (Turkey)
Alfa-1-Antikimotripsin Ag:MevcEşik:Zmlı:Doku:Srl:İmmün boyama

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=10461-2