104683-8
1,1-Dimethoxyoctadecane (DMA 18:0) [Mass/volume] in DBS
Active
Part Description
LP182320-4 1,1-Dimethoxyoctadecane
Dimethyl acetals (DMAs), including DMA 16:0 (1,1-Dimethoxyhexadecane), DMA 18:0 (1,1-Dimethoxyoctadecane), and DMA 18:1 (1,1-dimethoxy-(9Z)octadecene), are indirect markers for plasmalogens, which play a critical role in oxidative protection, and cholesterol homeostasis. DMA levels may be measured in more stable specimens, such as cultured fibroblasts and red blood cells, to diagnosis defects in plasmalogen synthesis, including retinitis pigmentosa (RP), rhizomelic chondrodysplasia punctata and Zellweger disease spectrum. Schaefer et. al. (1995) reported that dominant, recessive, and isolated forms of RP were found to have higher ratios of DMA 16:0/C16:0, DMA 18:0/C18:0 and DMA 18:1n9/C18:1n9 compared to controls. For X-linked RP, only the DMA 18:1n9/C18:1n9 ratio was significantly higher than in controls. Methods such as gas chromatography with flame detection of dimethyl acetals may be used for identification and quantification of DMAs.
Source: Regenstrief LOINC, PMID:7595066
Fully-Specified Name
- Component
- 1,1-Dimethoxyoctadecane
- Property
- MCnc
- Time
- Pt
- System
- Bld.dot
- Scale
- Qn
- Method
Additional Names
- Short Name
- DMA 18:0 DBS-mCnc
- Display Name
- 1,1-Dimethoxyoctadecane (DMA 18:0) (DBS) [Mass/Vol]
- Consumer Name Alpha Get Info
- 1,1-Dimethoxyoctadecane (DMA 18:0), Dried blood spot
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.78
- Last Updated
- Version 2.78
- Order vs. Observation
- Both
Member of these Panels
LOINC | Long Common Name |
---|---|
104687-9 | Dimethylacetal (DMA) panel - DBS |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | 1,1-Dimetoxioctadecano: Synonyms: Cuantitativo |
it-IT | Italian (Italy) | 1,1-Dimetossi ottadecano: Synonyms: Chimica Concentrazione di Massa Punto nel tempo (episodio) Sangue Spot sangue secco |
nl-NL | Dutch (Netherlands) | 1,1-dimethoxyoctadecaan: |
ru-RU | Russian (Russian Federation) | 1,1-Диметоксиоктадекан: Synonyms: Количественный Кровь Кровь сухая капля Массовая концентрация Точка во времени; |
tr-TR | Turkish (Turkey) | 1,1-Dimetoksioktadekan: |
zh-CN | Chinese (China) | 1,1-二甲氧基十八碳烷: Synonyms: 1,1-二甲氧基十八烷; |
Example Units
Unit | Source |
---|---|
ug/mL | Example UCUM Units |
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