104693-7
Ethyl glucuronide [Presence] in Saliva (oral fluid) by Screen method
Active
Part Descriptions
LP36909-7 Ethyl glucuronide
Ethyl glucuronide is a natural human metabolite of Ethanol generated in the liver by UDP glucuonyltransferase. Glucuronidation is used to assist in the excretion of toxic substances, drugs or other substances that cannot be used as an energy source. Glucuronic acid is attached via a glycosidic bond to the substance, and the resulting glucuronide, which has a much higher water solubility than the original substance, is eventually excreted by the kidneys.
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database,
Ethyl glucuronide
LP36909-7 Ethyl glucuronide
Ethyl glucuronide (EtG), a metabolite of ethyl alcohol formed in the body by glucuronidation following ethanol exposure, is a biomarker for ethanol use and a monitor to document alcohol abstinence in circumstances where drinking is prohibited, such as by the military, in professional monitoring programs, in schools, liver transplant clinics, or in recovering alcoholic patients. A disadvantage of the test is that because EtG can be detected at very low levels, it can also be positive after exposure to alcohol from non-beverage sources such as mouthwash, foods, over-the-counter medications, or incidental exposure, which can lead to false positives. PMID: 19371464 PMID: 19340678 PMID: 19007508
Source: Regenstrief LOINC,
PMID: 19340678
LP7565-7 Saliva
Saliva is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. PMID: 17268583
Source: Regenstrief LOINC
LP262420-5 Saliva DRUG/TOX
Oral fluid (or saliva) is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. The test procedures that use oral fluid for drug screening are usually similar to those for other specimens but adapted for oral fluid. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Drugs present in oral fluid are often the parent drug rather than a metabolite and tests kits reflect those differences. Concentrations of cocaine, amphetamines and some opioids in oral fluid are either similar or higher than concentrations in plasma. The concentration of tetrahydrocannabinol (THC) in oral fluid is similar to that of plasma, though in cases where recent ingestion has occurred, levels may be higher due to the significant local absorption in the oral cavity. Confirmatory testing on oral fluid using liquid chromatography-mass spectrometry (LC-MS) is highly sensitive and specific even on relatively small sample sizes. An increased understanding of pharmacokinetics in oral fluid has flourished inover the last ten years has allowed the correlation of . As a result, the concentrations of various drugs in oral fluid have been correlated to blood concentrations and the effects they have on the individual. PMID: 17268583
Source: Regenstrief LOINC
LOINC Names Get Info
- Fully-Specified Name
- Ethyl Glucuronide:
PrThr: Pt: Saliva: Ord: Screen - Long Common Name
- Ethyl glucuronide [Presence] in Saliva (oral fluid) by Screen method
- Short Name
- Ethyl glucuronide Sal Ql Scn
- Display Name
- Ethyl glucuronide Screen Ql (Sal)
- Consumer Name Alpha Get Info
- Ethyl glucuronide, Saliva
Part Model Get Info
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.78
- Last Updated
- Version 2.78 (ADD)
- Order vs. Observation
- Both
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Ethylglukuronid: |
| el-GR | Greek (Greece) | Αιθυλο-γλυκουρονίδιο: Synonyms: DRUG/TOX Ord PrThr Pt Αιθυλο-γλυκουρονίδιο Έλεγχος Σίελος |
| es-ES | Spanish (Spain) | Etil glucurónido: |
| fr-BE | French (Belgium) | Éthylglucuronide: |
| fr-FR | French (France) | Éthylglucuronide: |
| fr-CA | French (Canada) | Éthylglucuronide: |
| it-IT | Italian (Italy) | Etil glucuronide: Synonyms: Livelli farmacologici e tossicologia Presenza o Soglia Punto nel tempo (episodio) Screening tossicologico |
| nl-NL | Dutch (Netherlands) | ethylglucuronide: |
| pl-PL | Polish (Poland) | Glukuronid etylu: Synonyms: EtG |
| ru-RU | Russian (Russian Federation) | Этил глюкуронид: Synonyms: Порядковый Токсикологический скрининг Точка во времени; |
| tr-TR | Turkish (Turkey) | Etil glukuronid: Synonyms: Mevcut |
| zh-CN | Chinese (China) | 乙基葡糖苷酸: Synonyms: 乙基葡萄糖醛酸苷; |
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Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://