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LP14255-1   Cytomegalovirus
Cytomegalovirus is a member of the family Herpesviridae and also known as Human Herpesvirus-5 (HHV-5). It contains a linear double-stranded DNA encased in an icosahedral capsid that is surrounded by a viral envelope. It replicates slowly and may take weeks for the infection to become visible microscopically. Its life cycle includes a lytic and a latent phase. During the lytic phase the cytoskeleton of the infected cell is disrupted and becomes very large. The enlarged cell eludes detection by natural killer (NK) cells by encoding UL16. UL16 is a protein that binds to the ligand NDG2D which is a surface receptor on NK cells and, when blocked, prevents the CMV infected cell from apoptotic signaling to NK cells to destroy it.https://pedclerk.bsd.uchicago.edu/page/cytomegalovirus-cmv In the US one in three children are infected by CMV by the age of five and over half of adults are infected by age 40. Infection with CMV is mostly asymptomatic. Symptoms when present include fever, sore throat, fatigue, swollen glands. CMV can occasionally lead to mononucleosis or hepatitis. Immunocompromised patients experience much more acute symptoms that can affect the eyes, lungs, liver, esophagus, stomach, and intestines. For babies born with CMV, involvement with the brain, spleen, lung, liver can occur. In addition, there may be growth problems and hearing loss which is the most common symptom in congenital CMV infection. CMV is transmitted in urine, saliva, blood, tears, semen and breast milk by direct contact. Normally no treatment is necessary, but for severe cases medication is available.https://www.cdc.gov/cmv/overview.html Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Cytomegalovirus DNA:PrThr:Pt:{Specimen}:Ord:{Molgen}
Long Common Name
Cytomegalovirus DNA [Presence] in Specimen by Molgen
Short Name
CMV DNA Spec Ql
Display Name
CMV DNA Molgen Ql (Specimen)
Consumer Name Alpha Get Info
Cytomegalovirus (CMV), Specimen

Part Model Get Info

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.78
Last Updated
Version 2.83 (MAJ)
Order vs. Observation
Both

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Cytomegalovirus DNA:Přítomnost nebo práh:Časový bod:XXX:Ordinální:Molekulární genetika
el-GRGreek (Greece)Κυτταρομεγαλοϊός DNA:PrThr:Pt:XXX:Ord:Μοριακή γενετική
Synonyms: DNA MICRO Ord PrThr Pt XXX Κυτταρομεγαλοϊός Μοριακή γενετική
es-ESSpanish (Spain)Citomegalovirus ADN:PrThr:Punto temporal:XXX:Ord:Genética molecular
fr-FRFrench (France)Cytomégalovirus ADN:Présence/Seuil:Ponctuel:Milieux divers:Qualitatif:Biologie moléculaire
it-ITItalian (Italy)Citomegalovirus DNA:PrThr:Pt:XXX:Ord:Molgen
Synonyms: Genetica molecolare Microbiologia Presenza o Soglia Punto nel tempo (episodio)
nl-NLDutch (Netherlands)Cytomegalovirus DNA:aanwezigheid:moment:XXX:ordinaal:moleculair genetisch onderzoek
Synonyms: molgen
pl-PLPolish (Poland)Wirus cytomegalii DNA:granica wykrywalności:punkt w czasie:XXX:uporządkowany:genetyka molekularna
Synonyms: Cytomegalowirus diagnostyka molekularna DNA Cytomeglaowirusa Kwas deoksyrybonukleinowy
ru-RURussian (Russian Federation)Цитомегаловирус ДНК:PrThr:ТчкВрм:XXX:Пор:МолГен
Synonyms: Порядковый Точка во времени;Момент
tr-TRTurkish (Turkey)Cytomegalovirus DNA:MevcEşik:Zmlı:XXX:Srl:Molgen
Synonyms: Mevcut
zh-CNChinese (China)巨细胞病毒 DNA:存在情况或阈值:时间点:XXX:序数型:分子遗传学类实验室方法
Synonyms: CMV DNA CMV;涎腺病毒;细胞巨化病毒;细胞肥大病毒 不明的;其他;将在相应消息内其他部分之中加以详细说明;未作详细说明的;未作说明的;未做说明的标本;未加规定的;未加说明的标本;杂项 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应 去氧核糖核酸;脱氧核糖核酸 去氧核糖核酸;脱氧核糖核酸;脱氧核糖核酸（Deoxyribonucleic acid，DNA） 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 时刻;随机;随意;瞬间

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