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Part Description

LP16800-2   Aluminum
Aluminium (Al) is a metal which is distributed throughout our environment. It has been used since approximately 1887. Al is widely used in multiple industries and consumer products. It has no known function in biology. Al usually enters the human body via cooking utensils or pharmicological agents such as antacids (Al (OH)3 )and antiperspirants. Aluminum salts are remarkably nontoxic, aluminum sulfate having an LD50 of 6207 mg/kg (oral, mouse), which corresponds to 500 grams for an 80 kg (180 lb) person. Aluminum is excreted by filtration by the glomeruli of the kidney. Patients in renal failure lose the ability to clear aluminum, and aluminum toxicity may be a concern. Aluminum accumulates in the blood and binds to proteins such as albumin, and then distributed throughout the body.Because aluminum competes with calcium for absorption, increased amounts of dietary aluminum may contribute to the reduced skeletal mineralization (osteopenia) observed in preterm infants and infants with growth retardation. In very high doses, aluminum is associated with altered function of the blood-brain barrier. A small percentage of people are allergic to aluminum and experience contact dermatitis, digestive disorders, vomiting or other symptoms upon contact or ingestion of products containing aluminum. In those without allergies, aluminum is not as toxic as heavy metals, but there is evidence of some toxicity if consumed in amounts greater than 40 mg/day per kg of body mass. Aluminum is classified as a non-carcinogen by the US Department of Health and Human Services. In case of suspected sudden intake of a large amount of aluminum, deferoxamine mesylate may be given to help eliminate it from the body by chelation. (Tietz: Clinical Guide to Laboratory Tests, Fourth Edition)
The mechanism of how the neurotoxicity of AI occurs is still unclear. Evidence suggests that oxidative stress and inflammatory processes lead to cell death. As a neurotoxin, Al is considered has been linked to the development of neurodegenerative diseases, including Alzheimer's disease (AD), dementia, Amyotrophic Lateral Sclerosis (ALS) Parkinsonism and even Gulf war syndrome. PMID: 27479193 (for human medicine)

Veterinary Medicine:
In veterinary medicine, the impact of aluminum toxicity is similar. An animal proven to have aluminum toxicity from an ingested foreign body had symptoms of muscle twitching and convulsions during exercise, which worsened to weakened limbs and coma until the source of the toxicity was removed. PMID: 23609067 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Aluminum Ab.IgE:ACnc:Pt:Ser:Qn:
Long Common Name
Aluminum IgE Ab [Units/volume] in Serum
Short Name
Aluminum IgE Qn
Display Name
Aluminum IgE Qn (S)
Consumer Name Alpha Get Info
Aluminum allergy test

Part Model Get Info

  • Component
    Aluminum Ab.IgE
    LP441297-1
    • Analyte
      Aluminum Ab.IgE
      LP441297-1
      • Component Numerator
        Aluminum Ab.IgE
        LP441297-1
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    ACnc
    LP6773-8
  • Time
    Pt
    LP6960-1
  • System
    Ser
    LP7567-3
    • System Core
      Ser
      LP7567-3
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
ALLERGY
Type
Laboratory
First Released
Version 2.78
Last Updated
Version 2.78 (ADD)
Order vs. Observation
Observation

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Hliník Ab.IgE:Arbitrární koncentrace:Časový bod:Sérum:Kvantitativní:
el-GRGreek (Greece)Αλουμίνιο Ab.IgE:ACnc:Pt:Ορός:Qn:
Synonyms: Ab.IgE ACnc ALLERGY Pt Qn Αλουμίνιο Ανοσοσφαιρίνη E Αντίσωμα Ορός
es-ESSpanish (Spain)Aluminio IgE:Concentración arbitraria:Punto temporal:Suero:Qn:
Synonyms: Cuantitativo
et-EEEstonian (Estonia)Alumiinium antikehad.IgE:Acnc:Pt:S:Qn:
Synonyms: Immuunglobuliin E Juhuslik Kvantitatiivne Seerum
fr-BEFrench (Belgium)Aluminium Anticorps.IgE:Concentration arbitraire:Temps ponctuel:Sérum:Quantitatif:
Synonyms: Al Anticorps
fr-FRFrench (France)Aluminium Ac IgE:Arbitraire/Volume:Ponctuel:Sérum:Numérique:
fr-CAFrench (Canada)Aluminium, IgE:Concentration arbitraire:Temps ponctuel:Sérum:Quantitatif:
it-ITItalian (Italy)Alluminio Ab.IgE:ACnc:Pt:Siero:Qn:
Synonyms: anticorpi anti-IgE anticorpo Concentrazione Arbitraria Punto nel tempo (episodio) Risposta agli antigeni Siero
nl-NLDutch (Netherlands)aluminium As.IgE:eenheid/volume:moment:serum:kwantitatief:
Synonyms: antistof; antilichaam
ru-RURussian (Russian Federation)Алюминий Ат.IgE:ПроизвКонц:ТчкВрм:Сыв:Колич:
Synonyms: Антитело Количественный Произвольная концентрация Сыворотка Точка во времени;Момент
tr-TRTurkish (Turkey)Aluminyum Ab.IgE:SçKons:Zmlı:Ser:Kant:
Synonyms: Ak Ak.IgE
zh-CNChinese (China)铝 抗体.IgE:任意型浓度:时间点:血清:定量型:
Synonyms: Ab.IgE;IgE;抗体 IgE Ab;自身抗体 AL 任意型浓度(单位体积);任意浓度;单位体积的任意单位数;人工型浓度 免疫球蛋白 E 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间

Example Units

UnitSource
k[IU]/LExample UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=104854-5