LOINC
Version 2.68

10487-7HMB-45 Ag [Presence] in Tissue by Immune stainActive

Part Description

LP14668-5   HMB-45
HMB-45 is a monoclonal antibody that reacts against an antigen present in melanocytic tumors such as melanomas, and stands for Human Melanoma Black. It is used in anatomic pathology as a marker for such tumors.

The antibody was generated to an extract of melanoma. It reacts positively against melanocytic tumors but not other tumors, thus demonstrating specificity and sensitivity. The antibody also reacts positively against junctional nevus cells but not intradermal nevi, and against fetal melanocytes but not normal adult melanocytes.

HMB-45 is nonreactive with almost all non-melanoma human malignancies, with the exception of rare tumors showing evidence of melanogenesis (e.g., pigmented schwannoma, clear cell sarcoma) or tumors associated with tuberous sclerosis complex (angiomyolipoma and lymphangiomyoma). Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

Fully-Specified Name

Component
HMB-45 Ag
Property
PrThr
Time
Pt
System
Tiss
Scale
Ord
Method
Immune stain

Additional Names

Short Name
HMB45 Ag Tiss Ql ImStn
Display Name
HMB-45 Ag Immune stain Ql (Tiss)

Basic Attributes

Class
PATH
Type
Laboratory
First Released
Version 1.0i
Last Updated
Version 2.56
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Language Variants Get Info

zh-CNChinese (CHINA)
HMB-45 抗原:存在情况或阈值:时间点:组织与涂片:序数型:免疫染色法
nl-NLDutch (NETHERLANDS)
HMB-45 Ag:aanwezigheid:moment:weefsel en uitstrijkjes:ordinaal:immunokleuring
et-EEEstonian (ESTONIA)
HMB-45 antigeen:PrThr:Pt:Tis:Ord:Immuunvärv
fr-BEFrench (BELGIUM)
HMB-45 Ag:PrThr:Temps ponctuel:Tissu:Ordinal:Coloration immunologique
fr-CAFrench (CANADA)
HMB-45 , Ag:Présence-Seuil:Temps ponctuel:Tissu:Ordinal:Coloration immunologique
fr-FRFrench (FRANCE)
HMB-45 antigène:Présence/Seuil:Ponctuel:Tissu:Qualitatif:Coloration immune
it-ITItalian (ITALY)
HMB-45 , Ag:PrThr:Pt:Tessuto:Ord:Colorazione immunologica
ko-KRKorean (KOREA, REPUBLIC OF)
HMB-45 항원:임의농도:검사시점:조직:순위척도:면역염색
pt-BRPortuguese (BRAZIL)
HMB-45 Ag:ACnc:Pt:Tecido:Ord:Imunocoloração
ru-RURussian (RUSSIAN FEDERATION)
HMB-45 Аг:PrThr:ТчкВрм:Тк:Пор:Иммуногистохимическая окраска
es-ARSpanish (ARGENTINA)
antígeno HMB-45:concentración arbitraria:punto en el tiempo:tejido, no especificado:ordinal:tinción inmunológica
es-ESSpanish (SPAIN)
HMB-45 Antígeno:PrThr:Punto temporal:Tejido:Ord:Tinción de inmunohistoquímica
tr-TRTurkish (TURKEY)
HMB-45 Ag:MevcEşik:Zmlı:Doku:Srl:İmmün boyama

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=10487-7