10487-7HMB-45 Ag [Presence] in Tissue by Immune stainActive
Part Description
LP14668-5 HMB-45
HMB-45 is a monoclonal antibody that reacts against an antigen present in melanocytic tumors such as melanomas, and stands for Human Melanoma Black. It is used in anatomic pathology as a marker for such tumors.
The antibody was generated to an extract of melanoma. It reacts positively against melanocytic tumors but not other tumors, thus demonstrating specificity and sensitivity. The antibody also reacts positively against junctional nevus cells but not intradermal nevi, and against fetal melanocytes but not normal adult melanocytes.
HMB-45 is nonreactive with almost all non-melanoma human malignancies, with the exception of rare tumors showing evidence of melanogenesis (e.g., pigmented schwannoma, clear cell sarcoma) or tumors associated with tuberous sclerosis complex (angiomyolipoma and lymphangiomyoma).
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia, Wikipedia
Fully-Specified Name
- Component
- HMB-45 Ag
- Property
- PrThr
- Time
- Pt
- System
- Tiss
- Scale
- Ord
- Method
- Immune stain
Additional Names
- Short Name
- HMB45 Ag Tiss Ql ImStn
- Display Name
- HMB-45 Ag Immune stain Ql (Tiss)
- Consumer Name Alpha
- HMB-45 antigen, Tissue
Basic Attributes
- Class
- PATH
- Type
- Laboratory
- First Released
- Version 1.0i
- Last Updated
- Version 2.56
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
Language Variants Get Info
- zh-CNChinese (China)
- HMB-45 抗原:
存在情况或阈值: 时间点: 组织与涂片: 序数型: 免疫染色法 - nl-NLDutch (Netherlands)
- HMB-45 Ag:
aanwezigheid: moment: weefsel en uitstrijkjes: ordinaal: immunokleuring - et-EEEstonian (Estonia)
- HMB-45 antigeen:
PrThr: Pt: Tis: Ord: Immuunvärv - fr-BEFrench (Belgium)
- HMB-45 Ag:
PrThr: Temps ponctuel: Tissu: Ordinal: Coloration immunologique - fr-CAFrench (Canada)
- HMB-45 , Ag:
Présence-Seuil: Temps ponctuel: Tissu: Ordinal: Coloration immunologique - fr-FRFrench (France)
- HMB-45 antigène:
Présence/Seuil: Ponctuel: Tissu: Qualitatif: Coloration immune - it-ITItalian (Italy)
- HMB-45 , Ag:
PrThr: Pt: Tessuto: Ord: Colorazione immunologica - ko-KRKorean (Korea, Republic of)
- HMB-45 항원:
임의농도: 검사시점: 조직: 순위척도: 면역염색 - pt-BRPortuguese (Brazil)
- HMB-45 Ag:
ACnc: Pt: Tecido: Ord: Imunocoloração - ru-RURussian (Russian Federation)
- HMB-45 Аг:
PrThr: ТчкВрм: Тк: Пор: Иммуногистохимическая окраска - es-ARSpanish (Argentina)
- antígeno HMB-45:
concentración arbitraria: punto en el tiempo: tejido, no especificado: ordinal: tinción inmunológica - es-MXSpanish (Mexico)
- HMB-45 Ag:
Presencia o umbral: Punto temporal: Tejido y frotis: Ordinal: Mancha inmune - es-ESSpanish (Spain)
- HMB-45 Antígeno:
PrThr: Punto temporal: Tejido: Ord: Tinción de inmunohistoquímica - tr-TRTurkish (Turkey)
- HMB-45 Ag:
MevcEşik: Zmlı: Doku: Srl: İmmün boyama
LOINC FHIR® API Example - CodeSystem Request Get Info
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=10487-7
LOINC Copyright
Copyright © 2022 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright