Version 2.78

Part Description

LP200472-1   Escherichia coli enterotoxigenic ltA+st1a+st1b genes
Enterotoxigenic Escherichia coli (ETEC) produces a heat-labile (LT) and a heat-stable (ST) enterotoxin, both of which cause severe diarrhea in both humans and animals. ST is an extracellular toxin which is comprised of a methanol-soluble (STa) toxin and a methanol-insoluble (STb) toxin. The sta gene encodes the STa toxin and the stb gene encodes the STb toxin. [UniProt: Q70Q79]; [UniProt: Q70Q73] STa combines to its enterocyte receptor, guanylate cyclase, which causes intestinal secretion and diarrhea. PMID: 8528070 The STb enterocyte receptor is the protein sulfatide. After STb binds to sulfatide, it is engulfed by the enterocyte. It then activates the pertussis toxin-sensitive G protein which opens the ligand-gated calcium ion channel, allowing an influx of calcium ions. A subsequent secretion of chloride ions, stimulation of arachidonic acid release, and production of prostaglandin E2 and 5-dyroxytryptamine leads to an efflux of water, bicarbonate ions, sodium ions, and chloride ions into the intestinal space, all of which leads to watery diarrhea. PMID: 23716609 Source: Regenstrief LOINC

Fully-Specified Name

Component
Escherichia coli enterotoxigenic ltA+st1a+st1b genes
Property
PrThr
Time
Pt
System
Stool
Scale
Ord
Method

Additional Names

Long Common Name
Escherichia coli enterotoxigenic ltA+st1a+st1b genes [Presence] in Stool
Short Name
ETEC ltA+st1a+st1b Stl Ql
Display Name
E. coli enterotoxigenic ltA+st1a+st1b genes Ql (Stl)
Consumer Name Alpha Get Info
Escherichia coli enterotoxigenic ltA+st1a+st1b genes, Stool

Example Answer List: LL744-4

Source: Regenstrief Institute
Answer Code Score Answer ID
Detected LA11882-0
Not detected LA11883-8

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.78
Last Updated
Version 2.78
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) toxinas ltA+st1a+st1b de Escherichia coli enterotoxigénica:PrThr:Punto temporal:Heces:Ord:
it-IT Italian (Italy) Escherichia coli enterotossigeni geni ItA+st1a+st1b:PrThr:Pt:Feci:Ord:
Synonyms: ETEC Microbiologia Presenza o Soglia Punto nel tempo (episodio)
nl-NL Dutch (Netherlands) Escherichia coli enterotoxigene ltA + st1a + st1b genen:aanwezigheid:moment:feces:ordinaal:
Synonyms: E.coli; EAEC ontlasting; feces
tr-TR Turkish (Turkey) Escherichia coli enterotoxigenic ltA+st1a+st1b toksinleri:MevcEşik:Zmlı:Dışkı:Srl:
Synonyms: Gaita; feçes Mevcut
zh-CN Chinese (China) 大肠埃希菌肠产毒素型 ltA+st1a+st1b 基因:存在情况或阈值:时间点:大便:序数型:
Synonyms: E coli;大肠埃希氏杆菌;大肠埃希氏菌;大肠杆菌 产肠毒素性大肠埃希菌（E coli、大肠埃希氏杆菌、大肠埃希氏菌、大肠杆菌）;肠毒性大肠杆菌;肠产毒性大肠杆菌;ETEC 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 便;大肠运动;排便;粪便;肠运动 分子病理学 - 基因类 基因 大肠埃希菌（E coli、大肠埃希氏杆菌、大肠埃希氏菌、大肠杆菌）肠产毒素型（肠产毒素性、产肠毒素性、产肠毒素型、肠毒性、肠毒型、产肠毒性、产肠毒型） ltA+st1a+st1b 基因;肠产毒素型大肠埃希菌 ltA+st1a+st1b 基因 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 时刻;随机;随意;瞬间

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=105072-3