Version 2.80

Part Descriptions

LP30825-1   Guanidinoacetate
Guanidinoacetate is the immediate precursor of creatine. Guanidinoacetate methyltransferase (GAMT) is the enzyme responsible for converting guanidinoacetate to creatine, and GAMT deficiency causes is a rare, autosomal recessive disorder whose manifestations include seizures, developmental delay, learning difficulties, and autism. Motor function is relatively spared. GAMT deficiency leads to elevated levels of plasma and urine guanidinoacetate, and low plasma creatine and creatinine levels. Elevated levels of guanidinoacetate in the brain are one cause of seizures in patients with GAMT deficiency. The primary treatment is creatine supplementation, which may be combined with ornithine supplementation and arginine restriction. Early diagnosis and treatment may prevent organ damage and preserve cognitive function. If the diagnosis does not occur early and brain damage has already occurred at the time of diagnosis, creatine supplementation can still help control seizures and improve quality of life. PMID: 28119378 Source: Regenstrief LOINC

LP32032-2   Creatine
An amino acid that occurs in vertebrate tissues and in urine. In muscle tissue, creatine generally occurs as phosphocreatine. Creatine is excreted as CREATININE in the urine. Source: National Library of Medicine, MeSH 2006

Fully-Specified Name

Component
Guanidinoacetate/Creatine
Property
SRto
Time
Pt
System
Ser/Plas
Scale
Qn
Method

Additional Names

Long Common Name
Guanidinoacetate/Creatine [Molar ratio] in Serum or Plasma
Short Name
Guanidinoacetate/Creatine SerPl-sRto
Display Name
Guanidinoacetate/Creatine [Molar ratio]
Consumer Name Alpha Get Info
Guanidinoacetate/Creatine, Blood

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.78
Last Updated
Version 2.78 (ADD)
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
104537-6 Creatine, guanidinoacetate and creatinine panel - Serum or Plasma

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Γουανιδινοξικό/Κρεατίνη:SRto:Pt:Ορός/Πλάσμα:Qn:
Synonyms: SRto
es-ES Spanish (Spain) Guanidinoacetato/Creatina:Relacion de Sustancia:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
fr-FR French (France) Guanidinoacétate/créatine:Moles ratio:Ponctuel:Sérum/Plasma:Numérique:
it-IT Italian (Italy) Guanidinoacetato/Creatina:Srto:Pt:Siero/Plasma:Qn:
Synonyms: Chimica Plasma Punto nel tempo (episodio) Rapporto di sostanza Siero Siero o Plasma
nl-NL Dutch (Netherlands) guanidinoacetaat/creatine:molaire verhouding:moment:serum of plasma:kwantitatief:
ru-RU Russian (Russian Federation) Гуанидинацетат/Креатин:МольОтн:ТчкВрм:Сыв/Плаз:Колич:
Synonyms: Количественный Мольная доля;Молярная доля;Отношение концентраций Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) Guanidinoasetat/Kreatin:SOrn:Zmlı:Ser/Plaz:Kant:
Synonyms: SubsOranı
zh-CN Chinese (China) 胍基乙酸/肌酸:物质的量比率:时间点:血清/血浆:定量型:
Synonyms: Cr;甲胍;甲胍基乙酸;甲胍基醋酸;肌氨酸 GAA;胍乙酸;胍基醋酸 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 物质的量比值;物质的量比;摩尔比;摩尔比率;摩尔比值 甲胍乙酸 血清或血浆

Example Units

Unit Source
umol/mmol Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=105124-2