LOINC
Version 2.68

10515-5Thyroglobulin Ag [Presence] in Tissue by Immune stainActive

Part Descriptions

LP14697-4   Thyroglobulin
Thyroglobulin (Tg) is a protein produced by and used entirely within the thyroid gland. Thyroglobulin is used by the thyroid gland to produce the thyroid hormones thyroxine (T4) and triiodothyronine (T3). Thyroglobulin is stored in the thyroid in follicle cysts surrounded by colloid cells. Via a reaction with the enzyme thyroperoxidase, iodine is covalently bound to tyrosine residues in thyroglobulin molecules, forming monoiodotyrosine (MIT) and diiodotyrosine (DIT). Thyroxine is produced by linking two moieties of DIT. Combining one particle of MIT and one particle of DIT produces triiodothyronine. Proteases in lysosomes digest iodinated thyroglobulin, releasing T3 and T4. Thyroglobulin levels in the blood can be used as a tumor marker for certain kinds of thyroid cancer. Thyroglobulin levels in the blood can also be elevated in cases of Graves Disease. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Thyroglobulin (Wikipedia)

LP14697-4   Thyroglobulin
Thyroglobulin (Tg) is a glycoprotein homodimer produced by the thyroid gland. It is important in the synthesis of thyroxine and triiodothyronine, and is where the inactive forms of thyroid hormone and iodine are stored. Mutations in the Tg gene cause thyroid dyshormonogenesis resulting in goiter, and can be associated with moderate to severe congenital hypothyroidism. Polymorphisms in the Tg gene are associated with susceptibility to autoimmune thyroid diseases such as Graves disease or Hashimoto thyroiditis. [NCBI Gene ID:7038] Tg is an established tumor marker used in the diagnosis of differentiated thyroid carcinoma. [PMID: 9543128] Source: Regenstrief LOINC

Fully-Specified Name

Component
Thyroglobulin Ag
Property
PrThr
Time
Pt
System
Tiss
Scale
Ord
Method
Immune stain

Additional Names

Short Name
Thyroglob Ag Tiss Ql ImStn
Display Name
Thyroglobulin Ag Immune stain Ql (Tiss)

Basic Attributes

Class
PATH
Type
Laboratory
First Released
Version 1.0i
Last Updated
Version 2.56
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Language Variants Get Info

zh-CNChinese (CHINA)
甲状腺球蛋白 抗原:存在情况或阈值:时间点:组织与涂片:序数型:免疫染色法
nl-NLDutch (NETHERLANDS)
thyreoglobuline Ag:aanwezigheid:moment:weefsel en uitstrijkjes:ordinaal:immunokleuring
et-EEEstonian (ESTONIA)
Türeoglobuliin antigeen:PrThr:Pt:Tis:Ord:Immuunvärv
fr-BEFrench (BELGIUM)
Thyroglobuline Ag:PrThr:Temps ponctuel:Tissu:Ordinal:Coloration immunologique
fr-CAFrench (CANADA)
Thyroglobuline , Ag:Présence-Seuil:Temps ponctuel:Tissu:Ordinal:Coloration immunologique
fr-FRFrench (FRANCE)
Thyroglobuline antigène:Présence/Seuil:Ponctuel:Tissu:Qualitatif:Coloration immune
it-ITItalian (ITALY)
Tireoglobulina , Ag:PrThr:Pt:Tessuto:Ord:Colorazione immunologica
ko-KRKorean (KOREA, REPUBLIC OF)
갑상샘글로불린 항원:임의농도:검사시점:조직:순위척도:면역염색
pt-BRPortuguese (BRAZIL)
Tireoglobulina Ag:ACnc:Pt:Tecido:Ord:Imunocoloração
ru-RURussian (RUSSIAN FEDERATION)
Тиреоглобулин Аг:PrThr:ТчкВрм:Тк:Пор:Иммуногистохимическая окраска
es-ARSpanish (ARGENTINA)
antígeno de tiroglobulina:concentración arbitraria:punto en el tiempo:tejido, no especificado:ordinal:tinción inmunológica
es-ESSpanish (SPAIN)
Tiroglobulina Antígeno:PrThr:Punto temporal:Tejido:Ord:Tinción de inmunohistoquímica
tr-TRTurkish (TURKEY)
Tiroglobulin Ag:MevcEşik:Zmlı:Doku:Srl:İmmün boyama

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https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=10515-5