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Part Description

LP231983-0   Neutrophil membrane Ab
Antineutrophil membrane antibodies are antibodies that bind to antigens on the surface of neutrophils. Several specific antigens have been identified, but the IgG Fc receptor type 3b is the primary target. It was first recognized that these antibodies were a cause of autoimmune neutropenia (AIN) in 1975. Neutropenia is separated into three categories according to the risk of infection and based on the concentration of circulating neutrophils: mild neutropenia (1000-1500 cells/uL) moderate neutropenia (500-1000 cells/uL) and severe (less than 500 cells/uL). In some AIN the neutrophil numbers are normal but some functions are compromised including their ability to influence adhesion, aggregation, chemotaxis, phagocytosis and metabolic activation. AIN has two subcategories including primary AIN and secondary AIN. In primary AIN there is no association with another pathology. Primary AIN is most common in neonates and results in moderate to severe neutropenia, rarely leads to infection and is self-limiting. Secondary AIN usually occurs following a systemic haematologic disease including infectious diseases, solid or haematological neoplasms, neurological diseases, bone marrow or stem cell transplants, kidney transplants and the use of some drugs. In light of the difficulty in detecting autoimmune antineutrophil antibodies, it is recommended that both immunofluorescent and agglutination tests be performed. PMID: 16207350 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Neutrophil membrane Ab:PrThr:Pt:Ser/Plas:Ord:Aggl
Long Common Name
Neutrophil membrane Ab [Presence] in Serum or Plasma by Agglutination
Short Name
Neutrophil membrane Ab SerPl Ql Aggl
Display Name
Neutrophil membrane Ab Aggl Ql
Consumer Name Alpha Get Info
Neutrophil membrane antibody, Blood

Part Model Get Info

  • Component
    Neutrophil membrane Ab
    LP231983-0
    • Analyte
      Neutrophil membrane Ab
      LP231983-0
      • Component Numerator
        Neutrophil membrane Ab
        LP231983-0
        • Component Numerator Core
          Neutrophil membrane
          LP232480-6
        • Component Numerator Core Suffix
          Ab
          LP20667-9
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    PrThr
    LP217195-9
  • Time
    Pt
    LP6960-1
  • System
    Ser/Plas
    LP7576-4
    • System Core
      Ser/Plas
      LP7576-4
    • Super System
      NULL
       
  • Scale
    Ord
    LP7751-3
  • Method
    Aggl
    LP6106-1

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.78
Last Updated
Version 2.78 (ADD)
Order vs. Observation
Both

Member of these Panels

LOINCLong Common Name
105285-1Neutrophil Ab screen panel - Serum or Plasma

Member of these Groups Get Info

LOINC GroupGroup Name
LG51665-4Neutrophil membrane Ab|PrThr|Pt|ANYBldSerPl

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Neutrofily membrána Ab:Přítomnost nebo práh:Časový bod:Sérum/plazma:Ordinální:Aglutinace
el-GRGreek (Greece)Μεμβράνη ουδετερόφιλου Αντίσωμα:PrThr:Pt:Ορός/Πλάσμα:Ord:Συγκόλληση
Synonyms: Ord PrThr Pt SERO Αντίσωμα Μεμβράνη ουδετερόφιλου Ορός Ορός/Πλάσμα Ουδετερόφιλο Πλάσμα Συγκόλληση
es-ESSpanish (Spain)Membrana neutrófila Anticuerpos:PrThr:Punto temporal:Suero o Plasma:Ord:Aglutinación
fr-FRFrench (France)Membrane des polynucléaires neutrophiles Ac:Présence/Seuil:Ponctuel:Sérum/Plasma:Qualitatif:Agglutination
it-ITItalian (Italy)Membrana neutrofili Ab:PrThr:Pt:Siero/Plasma:Ord:Aggl
Synonyms: Agglutinazione anticorpo Plasma Presenza o Soglia Punto nel tempo (episodio) Siero Siero o Plasma Sierologia (anticorpi e la maggior parte degli ant
nl-NLDutch (Netherlands)neutrofiel membraan As:aanwezigheid:moment:serum of plasma:ordinaal:agglutinatie
Synonyms: antistof; antilichaam
pl-PLPolish (Poland)Neutrofil błona Ab:granica wykrywalności:punkt w czasie:surowica lub osocze:uporządkowany:aglutynacja
Synonyms: Błona neutrofila Neutrofil
zh-CNChinese (China)嗜中性粒细胞膜 抗体:存在情况或阈值:时间点:血清/血浆:序数型:凝集试验法
Synonyms: Ab;自身抗体 PMN;中性;中性白细胞;中性粒细胞;嗜中性;嗜中性白细胞;多形核;多形核白细胞;多形核粒细胞;多形核粒细胞（PMN） 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 凝集作用;凝集试验 嗜中性粒细胞（中性、中性粒、中性粒细胞、嗜中性、Neu）膜（细胞膜、胞膜） 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 时刻;随机;随意;瞬间 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类 血清或血浆

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=105287-7