LOINC
Version 2.68

10548-6Phenytoin Free/Phenytoin.total in Serum or PlasmaActive

Part Descriptions

LP14731-1   Phenytoin.free
Phenytoin-free levels detect the level of non-protein-bound phenytoin in the blood. It is used to measure therapeutic and toxic levels of the drug. Source: Regenstrief Institute

LP207910-3   free DRUG/TOX
The measurement of free (unbound) drug concentrations in plasma is important for certain drugs and has two advantages over measurement of total concentration: (1) the free concentration is independent of changes in plasma binding (e.g., due to changes in albumin), and (2) the free concentration is more directly related to both the efficacy and toxicity of the drug [PMID: 6636249] . For most drugs and the majority of patients, measuring the free and total concentrations is not necessary. However, for certain drugs, including some anticonvulsants and antibiotics, and specific patient populations, such as critically ill or immunosuppressed patients, the free concentration is a better indicator of therapeutic effect and potential toxicity. Source: Regenstrief LOINC

Fully-Specified Name

Component
Phenytoin.free/Phenytoin.total
Property
MFr
Time
Pt
System
Ser/Plas
Scale
Qn
Method

Additional Names

Short Name
Phenytoin Free MFr SerPl
Display Name
Phenytoin Free/Total phenytoin [Mass fraction]

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 1.0i
Last Updated
Version 2.30
Order vs. Observation
Observation

Language Variants Get Info

zh-CNChinese (CHINA)
苯妥英.游离型/苯妥英.总计:质量分数:时间点:血清/血浆:定量型:
nl-NLDutch (NETHERLANDS)
fenytoïne.vrij/fenytoïne.totaal:massafractie:moment:serum of plasma:kwantitatief:
et-EEEstonian (ESTONIA)
Fenütoiin.vaba/fenütoiin.üld:MFr:Pt:S/P:Qn:
fr-BEFrench (BELGIUM)
Phénytoïne.libre/Phénytoïne.totale:Fraction de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-CAFrench (CANADA)
Phénytoïne.libre/Phénytoïne.totale:Fraction de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-FRFrench (FRANCE)
Diphénylhydantoïne libre/diphénylhydantoïne totale:Fraction massique:Ponctuel:Sérum/Plasma:Numérique:
it-ITItalian (ITALY)
Fenitoina.libera/Fenitoina.totale:MFr:Pt:Siero/Plasma:Qn:
ko-KRKorean (KOREA, REPUBLIC OF)
유리페니토인/총페니토인:질량분획:검사시점:혈청/혈장:정량:
pt-BRPortuguese (BRAZIL)
Fenitoína.livre/Fenitoína.total:MFr:Pt:Sor/Plas:Qn:
ru-RURussian (RUSSIAN FEDERATION)
Фенитоин.свободный/Фенитоин.общий:МассДол:ТчкВрм:Сыв/Плаз:Колич:
es-ARSpanish (ARGENTINA)
fenitoína.libre/fenitoína.total:fracción de masa:punto en el tiempo:suero/plasma:cuantitativo:
es-ESSpanish (SPAIN)
Fenitoína libre/Fenitoína.total:Fracción de masa:Punto temporal:Suero o Plasma:Qn:
tr-TRTurkish (TURKEY)
Fenitoin.serb/Fenitoin.total:KütlFr:Zmlı:Ser/Plaz:Kant:

Example Units

Unit Source
% Example UCUM Units
% Original Submission
% REGENSTRIEF

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=10548-6