10548-6
Phenytoin Free/Phenytoin.total in Serum or Plasma
Active
Part Descriptions
LP14731-1 Phenytoin.free
Phenytoin-free levels detect the level of non-protein-bound phenytoin in the blood. It is used to measure therapeutic and toxic levels of the drug.
Source: Regenstrief Institute
LP207910-3 free DRUG/TOX
The measurement of free (unbound) drug concentrations in plasma is important for certain drugs and has two advantages over measurement of total concentration: (1) the free concentration is independent of changes in plasma binding (e.g., due to changes in albumin), and (2) the free concentration is more directly related to both the efficacy and toxicity of the drug [PMID: 6636249]. For most drugs and the majority of patients, measuring the free and total concentrations is not necessary. However, for certain drugs, including some anticonvulsants and antibiotics, and specific patient populations, such as critically ill or immunosuppressed patients, the free concentration is a better indicator of therapeutic effect and potential toxicity.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Phenytoin.free/Phenytoin.total
- Property
- MFr
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- Phenytoin Free MFr SerPl
- Display Name
- Phenytoin Free/Total phenytoin [Mass fraction]
- Consumer Name Alpha
- Free phenytoin/Phenytoin.total, Blood
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 1.0i
- Last Updated
- Version 2.73
- Order vs. Observation
- Observation
- Common Test Rank
- 2450
Language Variants
Tag | Language | Translation |
---|---|---|
zh-CN | Chinese (China) | 苯妥英.游离型/苯妥英.总计: Synonyms: |
fr-CA | French (Canada) | Phénytoïne.libre/Phénytoïne.totale: |
es-AR | Spanish (Argentina) | fenitoína.libre/fenitoína.total: |
et-EE | Estonian (Estonia) | Fenütoiin.vaba/fenütoiin.üld: Synonyms: |
pt-BR | Portuguese (Brazil) | Fenitoína.livre/Fenitoína.total: Synonyms: |
ko-KR | Korean (Korea, Republic Of) | 유리페니토인/총페니토인: |
es-ES | Spanish (Spain) | Fenitoína libre/Fenitoína.total: |
it-IT | Italian (Italy) | Fenitoina.libera/Fenitoina.totale: Synonyms: |
fr-FR | French (France) | Diphénylhydantoïne libre/diphénylhydantoïne totale: |
tr-TR | Turkish (Turkey) | Fenitoin.serb/Fenitoin.total: |
ru-RU | Russian (Russian Federation) | Фенитоин.свободный/Фенитоин.общий: Synonyms: |
nl-NL | Dutch (Netherlands) | fenytoïne.vrij/fenytoïne.totaal: |
fr-BE | French (Belgium) | Phénytoïne.libre/Phénytoïne.totale: |
es-MX | Spanish (Mexico) | Phenytoin.libre/Phenytoin.total: |
Example Units
Unit | Source |
---|---|
% | Example UCUM Units |
% | REGENSTRIEF |
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