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Term Description

This term is to test for the presence of a mutation within all coding regions of the following genes: H3-3A, H3-3B, H3C2, H3C3 and HIST2H3C. This test does not differenctiate between somatic and germline alterations.

Part Description

LP438338-8   H3 Clustered Histone 14 gene
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the telomeric copy. [provided by RefSeq, Aug 2015] Source: National Library of Medicine,

LOINC Names Get Info

Fully-Specified Name
H3 Clustered Histone 14 gene targeted mutation analysis:Find:Pt:Tiss:Doc:Molgen
Long Common Name
H3C14 gene targeted mutation analysis in Tissue by Molecular genetics method
Short Name
H3C14 gene Mut Anl Tiss
Display Name
H3C14 gene targeted mutation analysis Molgen Doc (Tiss)
Consumer Name Alpha Get Info
H3C14 gene targeted mutation analysis, Tissue

Part Model Get Info

  • Component
    H3 Clustered Histone 14 gene targeted mutation analysis
    LP438339-6
    • Analyte
      H3 Clustered Histone 14 gene targeted mutation analysis
      LP438339-6
      • Component Numerator
        H3 Clustered Histone 14 gene targeted mutation analysis
        LP438339-6
        • Component Numerator Core
          H3 Clustered Histone 14 gene
          LP438338-8
        • Component Numerator Core Suffix
          targeted mutation analysis
          LP32419-1
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    Find
    LP6813-2
  • Time
    Pt
    LP6960-1
  • System
    Tiss
    LP7641-6
    • System Core
      Tiss
      LP7641-6
    • Super System
      NULL
       
  • Scale
    Doc
    LP32888-7
  • Method
    Molgen
    LP6404-0

Basic Attributes

Class
MOLPATH
Type
Laboratory
First Released
Version 2.78
Last Updated
Version 2.78 (ADD)
Order vs. Observation
Order

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Gen H3 Clustered Histone 14 cílená mutační analýza:Nález:Časový bod:Tkáně a stěry:Dokument:Molekulární genetika
el-GRGreek (Greece)Γονίδιο H3 Clustered Histone 14 στοχευμένη ανάλυση μεταλλάξεων:Εύρεση:Pt:Ιστός:Doc:Μοριακή γενετική
Synonyms: Doc MOLPATH Pt Γονίδιο Γονίδιο H3 Clustered Histone 14 Εύρεση Ιστόνη Ιστός Μοριακή γενετική στοχευμένη ανάλυση μεταλλάξεων
fr-FRFrench (France)gène H3C14 H3 Clustered Histone 14 mutation cible trouvée:Recherche:Ponctuel:Tissu:Document:Biologie moléculaire
it-ITItalian (Italy)H3 Clustered Histone 14, gene analisi di mutazione mirata:Osservazione:Pt:Tessuto:Doc:Molgen
Synonyms: Gene H3C14 Genetica molecolare Osservazione Patologia molecolare Punto nel tempo (episodio) Tessuto & Strisci
nl-NLDutch (Netherlands)H3C14-gen doelgerichte mutatie-analyse:bevinding:moment:weefsel en uitstrijkjes:document:moleculair genetisch onderzoek
Synonyms: molgen targeted
pl-PLPolish (Poland)H3C14 gen ukierunkowana analiza mutacji:stwierdzenie:punkt w czasie:tkanka i rozmazy:dokument:genetyka molekularna
Synonyms: diagnostyka molekularna Gen H3C14
zh-CNChinese (China)H3 成簇组蛋白 14 基因 突变分析:发现:时间点:组织与涂片:文档型:分子遗传学类实验室方法
Synonyms: 临床文档型;临床文档;文档;文书;医疗文书;临床医疗文书 分子病理学;分子病理学试验 分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应 发现是一个原子型临床观察指标，并不是作为印象的概括陈述。体格检查、病史、系统检查及其他此类观察指标的属性均为发现。它们的标尺对于编码型发现可能是名义型，而对于叙述型文本之中所报告的发现，则可能是叙述型。;发现物;所见;结果;结论 基因突变分析 时刻;随机;随意;瞬间 未作说明的组织;组织;组织 & 涂片 组朊 遗传基因;遗传因子;吉恩;生物基因

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=105586-2