105879-1

Cytomegalovirus DNA [log units/volume] in Serum or Plasma

Active

Part Description

LP14255-1 Cytomegalovirus
Cytomegalovirus is a member of the family Herpesviridae and also known as Human Herpesvirus-5 (HHV-5). It contains a linear double-stranded DNA encased in an icosahedral capsid that is surrounded by a viral envelope. It replicates slowly and may take weeks for the infection to become visible microscopically. Its life cycle includes a lytic and a latent phase. During the lytic phase the cytoskeleton of the infected cell is disrupted and becomes very large. The enlarged cell eludes detection by natural killer (NK) cells by encoding UL16. UL16 is a protein that binds to the ligand NDG2D which is a surface receptor on NK cells and, when blocked, prevents the CMV infected cell from apoptotic signaling to NK cells to destroy it.https://pedclerk.bsd.uchicago.edu/page/cytomegalovirus-cmv In the US one in three children are infected by CMV by the age of five and over half of adults are infected by age 40. Infection with CMV is mostly asymptomatic. Symptoms when present include fever, sore throat, fatigue, swollen glands. CMV can occasionally lead to mononucleosis or hepatitis. Immunocompromised patients experience much more acute symptoms that can affect the eyes, lungs, liver, esophagus, stomach, and intestines. For babies born with CMV, involvement with the brain, spleen, lung, liver can occur. In addition, there may be growth problems and hearing loss which is the most common symptom in congenital CMV infection. CMV is transmitted in urine, saliva, blood, tears, semen and breast milk by direct contact. Normally no treatment is necessary, but for severe cases medication is available.https://www.cdc.gov/cmv/overview.html Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Cytomegalovirus DNA:LaCnc:Pt:Ser/Plas:Qn:
Long Common Name: Cytomegalovirus DNA [log units/volume] in Serum or Plasma
Short Name: CMV DNA SerPl-Log IU
Display Name: CMV DNA [Log units/Vol]
Consumer Name Alpha Get Info: Cytomegalovirus (CMV), Blood

Part Model Get Info

Component
Cytomegalovirus DNA
LP37883-3
- Analyte
  Cytomegalovirus DNA
  LP37883-3
  - Component Numerator
    Cytomegalovirus DNA
    LP37883-3
    - Component Numerator Core
      Cytomegalovirus
      LP14255-1
    - Component Numerator Core Suffix
      DNA
      LP32416-7
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
LaCnc
LP34325-8
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser/Plas
LP7576-4
- System Core
  Ser/Plas
  LP7576-4
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.78
Last Updated: Version 2.78 (ADD)
Order vs. Observation: Both

Member of these Groups Get Info

LOINC Group	Group Name
LG51974-0	Cytomegalovirus DNA\|LogIU/mL\|ANYBldSerPl

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Cytomegalovirus DNA:Koncentrace v log měřítku:Časový bod:Sérum/plazma:Kvantitativní:
el-GR	Greek (Greece)	Κυτταρομεγαλοϊός DNA:LaCnc:Pt:Ορός/Πλάσμα:Qn: Synonyms: DNA LaCnc MICRO Pt Qn Κυτταρομεγαλοϊός Ορός Ορός/Πλάσμα Πλάσμα
es-ES	Spanish (Spain)	Citomegalovirus ADN:Concentración logarítmica:Punto temporal:Suero o Plasma:Qn: Synonyms: Cuantitativo
et-EE	Estonian (Estonia)	Tsütomegaloviirus DNA:LaCnc:Pt:S/P:Qn: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-BE	French (Belgium)	Cytomégalovirus ADN:Concentration arbitraire exprimée en log:Temps ponctuel:Sérum/Plasma:Quantitatif: Synonyms: CMV Concentration Log
fr-FR	French (France)	Cytomégalovirus ADN:Log arbitraire/Volume:Ponctuel:Sérum/Plasma:Numérique:
fr-CA	French (Canada)	Cytomégalovirus, ADN:Concentration arbitraire exprimée en log:Temps ponctuel:Sérum/Plasma:Quantitatif:
it-IT	Italian (Italy)	Citomegalovirus DNA:LaCnc:Pt:Siero/Plasma:Qn: Synonyms: Concentrazione logaritmica Microbiologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma
nl-NL	Dutch (Netherlands)	Cytomegalovirus DNA:logaritmische eenheid/volume:moment:serum of plasma:kwantitatief:
pl-PL	Polish (Poland)	Wirus cytomegalii DNA:stężenie logarytmowo-jednostkowe:punkt w czasie:surowica lub osocze:ilościowy: Synonyms: Cytomegalowirus DNA Cytomeglaowirusa Kwas deoksyrybonukleinowy
ru-RU	Russian (Russian Federation)	Цитомегаловирус ДНК:LaCnc:ТчкВрм:Сыв/Плаз:Колич: Synonyms: Количественный Концентрация в логарифмических единицах Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR	Turkish (Turkey)	Cytomegalovirus DNA:LogKons:Zmlı:Ser/Plaz:Kant:
zh-CN	Chinese (China)	巨细胞病毒 DNA:对数型任意浓度:时间点:血清/血浆:定量型: Synonyms: CMV DNA CMV;涎腺病毒;细胞巨化病毒;细胞肥大病毒去氧核糖核酸;脱氧核糖核酸去氧核糖核酸;脱氧核糖核酸;脱氧核糖核酸（Deoxyribonucleic acid，DNA）可用数量表示的;定量性;数值型;数量型;连续数值型标尺对数任意浓度;任意浓度之对数微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）时刻;随机;随意;瞬间血清或血浆

Example Units

Unit	Source
{Log_copies}/mL	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.