106028-4

Cytomegalovirus DNA [Presence] in Genital specimen by NAA with probe detection

Active

Part Description

LP14255-1 Cytomegalovirus
Cytomegalovirus is a member of the family Herpesviridae and also known as Human Herpesvirus-5 (HHV-5). It contains a linear double-stranded DNA encased in an icosahedral capsid that is surrounded by a viral envelope. It replicates slowly and may take weeks for the infection to become visible microscopically. Its life cycle includes a lytic and a latent phase. During the lytic phase the cytoskeleton of the infected cell is disrupted and becomes very large. The enlarged cell eludes detection by natural killer (NK) cells by encoding UL16. UL16 is a protein that binds to the ligand NDG2D which is a surface receptor on NK cells and, when blocked, prevents the CMV infected cell from apoptotic signaling to NK cells to destroy it.https://pedclerk.bsd.uchicago.edu/page/cytomegalovirus-cmv In the US one in three children are infected by CMV by the age of five and over half of adults are infected by age 40. Infection with CMV is mostly asymptomatic. Symptoms when present include fever, sore throat, fatigue, swollen glands. CMV can occasionally lead to mononucleosis or hepatitis. Immunocompromised patients experience much more acute symptoms that can affect the eyes, lungs, liver, esophagus, stomach, and intestines. For babies born with CMV, involvement with the brain, spleen, lung, liver can occur. In addition, there may be growth problems and hearing loss which is the most common symptom in congenital CMV infection. CMV is transmitted in urine, saliva, blood, tears, semen and breast milk by direct contact. Normally no treatment is necessary, but for severe cases medication is available.https://www.cdc.gov/cmv/overview.html Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Cytomegalovirus DNA:PrThr:Pt:Genital:Ord:Probe.amp.tar
Long Common Name: Cytomegalovirus DNA [Presence] in Genital specimen by NAA with probe detection
Short Name: CMV DNA Genital Ql NAA+probe
Display Name: CMV DNA NAA+probe Ql (Genital specimen)
Consumer Name Alpha Get Info: Cytomegalovirus (CMV), Genital specimen

Part Model Get Info

Component
Cytomegalovirus DNA
LP37883-3
- Analyte
  Cytomegalovirus DNA
  LP37883-3
  - Component Numerator
    Cytomegalovirus DNA
    LP37883-3
    - Component Numerator Core
      Cytomegalovirus
      LP14255-1
    - Component Numerator Core Suffix
      DNA
      LP32416-7
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
PrThr
LP217195-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Genital
LP7261-3
- System Core
  Genital
  LP7261-3
- Super System
  NULL
Scale
Ord
LP7751-3
Method
Probe.amp.tar
LP6464-4

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.78
Last Updated: Version 2.78 (ADD)
Order vs. Observation: Observation

Member of these Groups Get Info

LOINC Group	Group Name
LG51698-5	Cytomegalovirus DNA\|PrThr\|Sys:ANYGU

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Cytomegalovirus DNA:Přítomnost nebo práh:Časový bod:Genitál:Ordinální:Amplifikace nukleových kyselin s detekcí sondou
el-GR	Greek (Greece)	Κυτταρομεγαλοϊός DNA:PrThr:Pt:Γεννητικά:Ord:Ανιχνευτής.ενίσχυση.στόχου Synonyms: DNA MICRO Ord PrThr Pt Ανιχνευτής Ανιχνευτής.ενίσχυση Ανιχνευτής.ενίσχυση.στόχου Γεννητικά Κυτταρομεγαλοϊός
es-ES	Spanish (Spain)	Citomegalovirus ADN:PrThr:Punto temporal:Genital:Ord:Sonda con amplificación dirigida
fr-BE	French (Belgium)	Cytomégalovirus ADN:PrThr:Temps ponctuel:Génital:Ordinal:Sonde avec amplification de la cible Synonyms: CMV
fr-FR	French (France)	Cytomégalovirus ADN:Présence/Seuil:Ponctuel:Prélèvement génital:Qualitatif:PCR amplification de cible
fr-CA	French (Canada)	Cytomégalovirus, ADN:Présence-Seuil:Temps ponctuel:Génital:Ordinal:Sonde avec amplification de la cible
it-IT	Italian (Italy)	Citomegalovirus DNA:PrThr:Pt:Genitale:Ord:Sonda.amp.tar Synonyms: Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
nl-NL	Dutch (Netherlands)	Cytomegalovirus DNA:aanwezigheid:moment:genitaal monster:ordinaal:probe-detectie Synonyms: probe.amp.tar
pl-PL	Polish (Poland)	Wirus cytomegalii DNA:granica wykrywalności:punkt w czasie:płciowy:uporządkowany:sonda.amplifikacja.cel Synonyms: amplifikacja kwasu nukleinowego z detekcją za pomocą sondy amplifikacja z detekcją za pomocą sondy Cytomegalowirus DNA Cytomeglaowirusa Kwas deoksyrybonukleinowy
ru-RU	Russian (Russian Federation)	Цитомегаловирус ДНК:PrThr:ТчкВрм:Генитальный:Пор:Проба.усил.миш Synonyms: ДНК проба;ДНК зонд Порядковый Проба с мишени усилением Точка во времени;Момент
tr-TR	Turkish (Turkey)	Cytomegalovirus DNA:MevcEşik:Zmlı:Genital:Srl:Prob.amf.hdf Synonyms: Mevcut
zh-CN	Chinese (China)	巨细胞病毒 DNA:存在情况或阈值:时间点:生殖器:序数型:探针法.基因扩增.靶向 Synonyms: CMV DNA CMV;涎腺病毒;细胞巨化病毒;细胞肥大病毒依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型借助扩增的探针方法;借助扩增的探针法;探针法.扩增借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向去氧核糖核酸;脱氧核糖核酸去氧核糖核酸;脱氧核糖核酸;脱氧核糖核酸（Deoxyribonucleic acid，DNA）外生殖器;尿生殖;泌尿和生殖系统;泌尿生殖;泌尿生殖器;生殖器(多用于指男性的外生殖器);生殖器官;生殖道;男生殖器存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）扩增型扩增性时刻;随机;随意;瞬间经过扩增的脱氧核糖核酸探针

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.