106787-5
Acetylcholine receptor Ab [Presence] in Serum by Immunoassay
Active
Part Descriptions
LP17722-7 Acetylcholine receptor
An acetylcholine receptor (abbreviated AChR) is an integral membrane protein that responds to the binding of the neurotransmitter acetylcholine. Nicotinic receptors are the primary mediator of the effects of nicotine. In myasthenia gravis, the receptor at the neuromuscular junction (NMJ) is targeted by antibodies, leading to muscle weakness. Muscarinic acetylcholine receptors can be blocked by the drugs atropine and scopolamine. Drugs such as the neuromuscular blocking agents bind reversibly to the nicotinic receptors in the neuromuscular junction and are used routinely in anesthesia. .
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Source: Wikipedia
, Acetylcholine receptor (Wikipedia)
LP36947-7 Acetylcholine receptor Ab
AChR antibodies and striated muscle antibodies have been detected in patients with Myasthenia gravis (MG), thymoma without neurological symptoms, and in patients with other autoimmune diseases, including, for example, Lambert-Eaton disease, myasthenic syndrome, rheumatoid arthritis, systemic lupus erythematosus, Graves disease, and autoimmune liver disease.
AChR antibodies are further characterized into three categories; binding, blocking, and modulating.
ACHR-binding antibodies are detected in 90% of patients with severe, generalized MG, and 50% of patients with ocular MG. ACHR-modulating antibodies and ACHR-blocking antibodies are detected in approximately 65% to 70% of MG patients.
Source: ARUP Laboratories
Fully-Specified Name
- Component
- Acetylcholine receptor Ab
- Property
- PrThr
- Time
- Pt
- System
- Ser
- Scale
- Ord
- Method
- IA
Additional Names
- Long Common Name
- Acetylcholine receptor Ab [Presence] in Serum by Immunoassay
- Short Name
- AChR Ab Ser Ql IA
- Display Name
- Acetylcholine receptor Ab IA Ql (S)
- Consumer Name Alpha Get Info
- Acetylcholine receptor antibody, Blood
Example Answer List: LL7009-5
| Answer | Code | Score | Answer ID |
|---|---|---|---|
| PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
| Borderline | LA4259-3 | ||
| NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 | ||
| InconclusiveCopyright http://snomed.info/sct ID:419984006 Inconclusive (qualifier value) | LA9663-1 |
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.79
- Last Updated
- Version 2.79 (ADD)
- Order vs. Observation
- Observation
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG51733-0 | Acetylcholine receptor Ab| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| el-GR | Greek (Greece) | Υποδοχέας ακετυλοχολίνης Αντίσωμα: Synonyms: PrThr |
| es-ES | Spanish (Spain) | Receptor de acetilcolina Anticuerpos: |
| et-EE | Estonian (Estonia) | Atsetüülkoliini retseptor antikehad: Synonyms: Järgarvuline Juhuslik Seerum |
| fr-CA | French (Canada) | Récepteur de l'acétylcholine, Ac: |
| fr-BE | French (Belgium) | Récepteur de l'acétylcholine Ac: Synonyms: Anticorps |
| it-IT | Italian (Italy) | Acetilcolina, recettore Ab: Synonyms: anticorpo Immunoassay Presenza o Soglia Punto nel tempo (episodio) Recettore dell''acetilcolina Siero Sierologia (anticorpi e la maggior parte degli ant |
| nl-NL | Dutch (Netherlands) | acetylcholinereceptor As: Synonyms: acetylcholine receptor antistof; |
| ru-RU | Russian (Russian Federation) | Ацетилхолин рецептор Ат: Synonyms: Антитело Ацетилхолиновый рецептор Порядковый Сыворотка Точка во времени; |
| tr-TR | Turkish (Turkey) | Asetilkolin reseptörü Ab: Synonyms: İmmünölçüm, immünoassay Mevcut |
| zh-CN | Chinese (China) | 乙酰胆碱受体 抗体: Synonyms: Ab; |
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