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Part Descriptions

LP30825-1   Guanidinoacetate
Guanidinoacetate is the immediate precursor of creatine. Guanidinoacetate methyltransferase (GAMT) is the enzyme responsible for converting guanidinoacetate to creatine, and GAMT deficiency causes is a rare, autosomal recessive disorder whose manifestations include seizures, developmental delay, learning difficulties, and autism. Motor function is relatively spared. GAMT deficiency leads to elevated levels of plasma and urine guanidinoacetate, and low plasma creatine and creatinine levels. Elevated levels of guanidinoacetate in the brain are one cause of seizures in patients with GAMT deficiency. The primary treatment is creatine supplementation, which may be combined with ornithine supplementation and arginine restriction. Early diagnosis and treatment may prevent organ damage and preserve cognitive function. If the diagnosis does not occur early and brain damage has already occurred at the time of diagnosis, creatine supplementation can still help control seizures and improve quality of life. PMID: 28119378 Source: Regenstrief LOINC

LP32032-2   Creatine
An amino acid that occurs in vertebrate tissues and in urine. In muscle tissue, creatine generally occurs as phosphocreatine. Creatine is excreted as CREATININE in the urine. Source: National Library of Medicine, MeSH 2006

LOINC Names Get Info

Fully-Specified Name
Guanidinoacetate/Creatine:SRto:Pt:Bld.dot:Qn:
Long Common Name
Guanidinoacetate/Creatine [Molar ratio] in DBS
Short Name
Guanidinoacetate/Creatine DBS-sRto
Display Name
Guanidinoacetate/Creatine (DBS) [Molar ratio]
Consumer Name Alpha Get Info
Guanidinoacetate/Creatine, Dried blood spot

Part Model Get Info

  • Component
    Guanidinoacetate/Creatine
    LP442467-9
    • Analyte
      Guanidinoacetate/Creatine
      LP442467-9
      • Component Numerator
        Guanidinoacetate
        LP30825-1
        • Component Numerator Core
          Guanidinoacetate
          LP30825-1
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        Creatine
        LP32032-2
        • Component Denominator Core
          Creatine
          LP32032-2
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    SRto
    LP6868-6
  • Time
    Pt
    LP6960-1
  • System
    Bld.dot
    LP21304-8
    • System Core
      Bld.dot
      LP21304-8
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.81
Last Updated
Version 2.81 (ADD)
Order vs. Observation
Both

Member of these Panels

LOINCLong Common Name
104191-2Guanidinoacetate methyltransferase (GAMT) deficiency newborn screening panel
54089-8Newborn screening panel American Health Information Community (AHIC)

Language Variants Get Info

TagLanguageTranslation
el-GRGreek (Greece)Γουανιδινοξικό/Κρεατίνη:SRto:Pt:Bld.dot:Qn:
Synonyms: Bld.dot CHEM Pt Qn SRto Αίμα Γουανιδινοξικό Κρεατίνη
es-ESSpanish (Spain)Guanidinoacetato/Creatina:Relacion de Sustancia:Punto temporal:gota de sangre (papel de filtro):Qn:
Synonyms: Cuantitativo
fr-FRFrench (France)Guanidinoacétate/créatine:Moles ratio:Ponctuel:Sang buvard:Numérique:
it-ITItalian (Italy)Guanidinoacetato/Creatina:Srto:Pt:Sangue.su carta da filtro:Qn:
Synonyms: Chimica Punto nel tempo (episodio) Rapporto di sostanza Sangue Spot sangue secco
nl-NLDutch (Netherlands)guanidinoacetaat/creatine:molaire verhouding:moment:gedroogde bloedspot:kwantitatief:
pl-PLPolish (Poland)Guanidynooctan/kreatyna:współczynnik molowy:punkt w czasie:sucha kropla krwi:ilościowy:
ru-RURussian (Russian Federation)Гуанидинацетат/Креатин:МольОтн:ТчкВрм:Кр.Сух.капл:Колич:
Synonyms: Количественный Кровь Кровь сухая капля Мольная доля;Молярная доля;Отношение концентраций Точка во времени;Момент
tr-TRTurkish (Turkey)Guanidinoasetat/Kreatin:SOrn:Zmlı:Kan.nokta:Kant:
Synonyms: SubsOranı
zh-CNChinese (China)胍基乙酸/肌酸:物质的量比率:时间点:全血.斑点:定量型:
Synonyms: Cr;甲胍;甲胍基乙酸;甲胍基醋酸;肌氨酸 GAA;胍乙酸;胍基醋酸 全血斑点(滤纸);滤纸;血液.斑点;血液斑点(滤纸) 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 物质的量比值;物质的量比;摩尔比;摩尔比率;摩尔比值 甲胍乙酸 血;血液

Example Units

UnitSource
umol/mmolExample UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=107506-8