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Part Descriptions

LP14393-0   Ganglioside GD1a
Gangliosides are a family of molecules that are present throughout the body but especially prevalent in cells of the nervous system. Specific gangliosides are named for the carbohydrate sequence they contain and have a unique distribution within the nervous system. The oligosaccharide groups on gangliosides act as cell surface markers that play a role in cellular recognition and cell-to-cell communication, and they also act as specific receptors for certain pituitary glycoprotein hormones and certain bacterial protein toxins such as cholera toxin.
Anti-ganglioside antibodies, primarily IgG, are present in the sera from approximately 60% of patients with Guillain-Barré syndrome (GBS), and antibodies against different gangliosides are associated with different forms of GBS.
1. Antibodies against GD1a/GD1b and GD1b/GT1b complexes have been found in patients with more severe GBS requiring mechanical ventilation;
2. Antibodies against GM1 or those against GalNAc-GD1a have been associated with acute motor axonal neuropathy;
3. Anti-GQ1b antibodies are specifically associated with a variant of GBS called Fisher syndrome, which is characterized by ophthalmoplegia and ataxia.
Detection of specific markers early in the course of GBS may help guide the plan of care. PMID: 21214559 Source: Regenstrief LOINC, PMID: 2121455

LP222219-0   Ganglioside
A ganglioside molecule consists of a glycosphingolipid (ceramide and oligosaccharide) with one or more sialic acid residues linked to the sugar chain. Molecules with one sialic acid residue are called monosialogangliosides (GM), those with two are called disialogangliosides (GD), and those with three are trisialogangliosides (GT). Gangliosides without any sialic acid residues are called asialogangliosides, while those that do not have a ceramide N-acyl group are called lysogangliosides. The number that typically is included at the end of the name indicates the order in which the molecule was discovered. For example, GM2 is a ganglioside with one sialic acid residue that was the second GM to be identified. Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Ganglioside GD1a Ab.IgG+IgM:PrThr:Pt:Ser:Ord:IA
Long Common Name
Ganglioside GD1a IgG+IgM Ab [Presence] in Serum by Immunoassay
Short Name
GD1a Gangl IgG+IgM Ser Ql IA
Display Name
Ganglioside GD1a IgG+IgM IA Ql (S)
Consumer Name Alpha Get Info
Ganglioside GD1a IgG+IgM, Blood

Part Model Get Info

  • Component
    Ganglioside GD1a Ab.IgG+IgM
    LP228504-9
    • Analyte
      Ganglioside GD1a Ab.IgG+IgM
      LP228504-9
      • Component Numerator
        Ganglioside GD1a Ab.IgG+IgM
        LP228504-9
        • Component Numerator Core
          Ganglioside GD1a
          LP14393-0
        • Component Numerator Core Suffix
          Ab.IgG+IgM
          LP32404-3
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    PrThr
    LP217195-9
  • Time
    Pt
    LP6960-1
  • System
    Ser
    LP7567-3
    • System Core
      Ser
      LP7567-3
    • Super System
      NULL
       
  • Scale
    Ord
    LP7751-3
  • Method
    IA
    LP217197-5

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.81
Last Updated
Version 2.81 (ADD)
Order vs. Observation
Both

Member of these Groups Get Info

LOINC GroupGroup Name
LG51962-5Ganglioside GD1a Ab.IgG+IgM|PrThr|Pt|ANYBldSerPl

Language Variants Get Info

TagLanguageTranslation
el-GRGreek (Greece)Γαγγλιοσίδη GD1a Αντισώματα IgG+IgM:PrThr:Pt:Ορός:Ord:IA
Synonyms: IA Ord PrThr Pt SERO Ανοσοσφαιρίνη G Ανοσοσφαιρίνη M Αντίσωμα Αντισώματα IgG Αντισώματα IgG & IgM Αντισώματα IgG+IgM Γαγγλιοσίδη Γαγγλιοσίδη GD1a Ορός
es-ESSpanish (Spain)Gangliosido GD1a IgG+IgM:PrThr:Punto temporal:Suero:Ord:IA
et-EEEstonian (Estonia)Gangliosiid GD1a antikehad.IgG+IgM:PrThr:Pt:S:Ord:IA
Synonyms: Immuunglobuliin G Immuunglobuliin M Järgarvuline Juhuslik Seerum
fr-BEFrench (Belgium)Ganglioside GD1a Anticorps.IgG+IgM:PrThr:Temps ponctuel:Sérum:Ordinal:IA
Synonyms: Anticorps
fr-FRFrench (France)Ganglioside GD1a Ac IgG+IgM:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Immunoanalyse
fr-CAFrench (Canada)Ganglioside GD1a, IgG+IgM:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:IA
it-ITItalian (Italy)Ganglioside GD1a Ab.IgG+IgM:PrThr:Pt:Siero:Ord:IA
Synonyms: anticorpi IgG anticorpi IgG e IgM Anticorpi IgG+IgM anticorpo Immunoassay Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant
nl-NLDutch (Netherlands)ganglioside GD1a As.IgG + IgM:aanwezigheid:moment:serum:ordinaal:immunoassay
Synonyms: antistof; antilichaam IA
pl-PLPolish (Poland)Gangliozyd GD1a Ab.IgG+IgM:granica wykrywalności:punkt w czasie:surowica:uporządkowany:metoda immunologiczna
Synonyms: IgG IgM Przeciwciała do gangliozydu GD1a przeciwciała IgG Przeciwciała IgG do gangliozydu GD1a przeciwciała IgG i IgM Przeciwciała IgG+IgM do gangliozydu GD1a
ru-RURussian (Russian Federation)Ганглиозид GD1a Ат.IgG+IgM:PrThr:ТчкВрм:Сыв:Пор:IA
Synonyms: Антитело Порядковый Сыворотка Точка во времени;Момент
tr-TRTurkish (Turkey)Gangliozid GD1a Ab.IgG+IgM:MevcEşik:Zmlı:Ser:Srl:İA
Synonyms: Ak Ak.IgG Ak.IgG+IgM İmmünölçüm, immünoassay Mevcut
zh-CNChinese (China)神经节苷脂 GD1a 抗体.IgG+IgM:存在情况或阈值:时间点:血清:序数型:免疫测定法
Synonyms: Ab.IgG;IgG;抗体 IgG Ab.IgG+IgM;IgG+IgM;抗体 IgG+抗体 IgM Ab;自身抗体 GD1a;神经节糖苷 GD1a 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验 免疫球蛋白 G 免疫球蛋白 M 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 抗体.IgG & IgM;抗体.IgG+IgM 时刻;随机;随意;瞬间 神经节糖苷 神经节苷脂 GD1a Ab 神经节苷脂 GD1a Ab.IgG 神经节苷脂 GD1a IgG 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

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CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=108207-2