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Status
TRIAL

Term Description

This term is intended to collate similar measurements for the LOINC SNOMED CT Collaboration in an ontological view. Additionally, it can be used to communicate a laboratory order, either alone or in combination with specimen or other information in the order. It may NOT be used to report back the measured patient value. https://lo.inc/ce2mb6

Part Descriptions

LP16474-6   Interleukin 6
Interleukin-6 (IL-6) is a protein that in humans is encoded by the IL6 gene.

IL-6 is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. It is secreted by T cells and macrophages to stimulate immune response to trauma, especially burns or other tissue damage leading to inflammation. In terms of host response to a foreign pathogen, IL-6 has been shown, in mice, to be required for resistance against the bacterium, Streptococcus pneumoniae. IL-6 is also a "myokine," a cytokine produced from muscle, and is elevated in response to muscle contraction. It is significantly elevated with exercise, and precedes the appearance of other cytokines in the circulation. During exercise, it is thought to act in a hormone-like manner to mobilize extracellular substrates and/or augment substrate delivery. Additionally, osteoblasts secrete IL-6 to stimulate osteoclast formation. Smooth muscle cells in the tunica media of many blood vessels also produce IL-6 as a pro-inflammatory cytokine. IL-6's role as an anti-inflammatory cytokine is mediated through its inhibitory effects on TNF-alpha and IL-1, and activation of IL-1ra and IL-10. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

LP16474-6   Interleukin 6
The Interleukins belong to the family termed cytokines. They are peptides used by immune and inflammatory cells to communicate and control cell operations. The cytokines have some similar actions to the Growth Factors but Growth Factors regulate proliferation of non-immune cells. Interleukin 6 is a 25,000 molecular weight glycoprotein produced primarily in macrophages, T cells, fibroblasts and endothelial cells. Its primary target cells are T and B cells and neutrophils. Its main actions are involvement in terminal differentiation of B cells to antibody secreting plasma cells, activation of T cells and stimulation of hepatocyte production of acute phase proteins. Interleukin stimulates Prolactin, Growth Hormone, Luteinizing Hormone, Follicle Stimulating Hormone and ACTH. Release is stimulated by Interleukin 1a and b, Vasoactive Intestinal Polypeptide, and Prostaglandin E2. Release is not affected by aspirin or indomethacin. Levels are elevated in multiple myeloma, rheumatoid arthritis, systemic lupus erythematosus, meningococcus meningitis and infectious peritonitis. Source: Inter Science Institute, Inter Science Institute

LP447904-6   {Measurement}
{Measurement} is a Property grouper part used to collate terms with comparable measurement-related properties. It encompasses the following LOINC Properties: ACnc, AFr, ARat, CAct, CCnc, CCnt, CRat, CSub, EntLen, LaCnc, LnCnc, Mass, MCnc, MCnt, MRat, MRto, MSCnc, MSRat, Naric, NCnc, NFr, Prctl, PrThr, Ratio, SatFr, SCnc, SCnt, SRat, SRto, Sub, ThreshNum, Titr, and TmMCn. Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Interleukin 6:{Measurement}:-:Ser/Plas:-:
Long Common Name
Interleukin 6 [Measurement] in Serum or Plasma
Short Name
Il6 Msmt SerPl
Display Name
Interleukin 6 [Measurement]
Consumer Name Alpha Get Info
Interleukin 6, Blood

Part Model Get Info

  • Component
    Interleukin 6
    LP16474-6
    • Analyte
      Interleukin 6
      LP16474-6
      • Component Numerator
        Interleukin 6
        LP16474-6
        • Component Numerator Core
          Interleukin 6
          LP16474-6
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    {Measurement}
    LP447904-6
  • Time
    -
    LP70420-2
  • System
    Ser/Plas
    LP7576-4
    • System Core
      Ser/Plas
      LP7576-4
    • Super System
      NULL
       
  • Scale
    -
    LP7747-1
  • Method
    NULL
     

Basic Attributes

Class
LABORDERS.ONTOLOGY
Type
Laboratory
First Released
Version 2.81
Last Updated
Version 2.81 (ADD)
Order vs. Observation
Order

Language Variants Get Info

TagLanguageTranslation
es-ESSpanish (Spain)Interleukina 6:Medición:-:Suero o Plasma:-:
fr-FRFrench (France)Interleukine-6:{Mesure}:-:Sérum/Plasma:-:
it-ITItalian (Italy)Interleuchina 6:{Misurazione}:-:Siero/Plasma:-:
Synonyms: Codici richieste di laboratorio LABORDERS.ONTOLOGY Misurazione Plasma Siero Siero o Plasma
pl-PLPolish (Poland)Interleukina 6:{Oznaczenie}:-:surowica lub osocze:-:
Synonyms: IL-6
zh-CNChinese (China)白细胞介素 6:{检测}:-:血清/血浆:-:
Synonyms: {测量};{测定};{检测结果};{测量结果};{测定结果} B 细胞分化因子-2;B 细胞刺激因子-2;BSF-2;B-细胞分化因子-2;B-细胞刺激因子-2;IFN-beta 2;IFN-β2;Il6;IL-6;MGI-2;杂交瘤生长因子;浆细胞瘤生长因子;白介素 6;白介素-6;白细胞介素-6;肝细胞刺激因子;髓系分化诱导因子 IL 多重;多重型;多重标尺类型;多重精度类型 实验室检验项目医嘱类;检验项目医嘱;检验项目申请;化验项目申请 检验申请.本体;实验室检验医嘱.本体 白介 白介素 白细胞介素（Interleukin，白介素，IL） 血清或血浆

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=108730-3