108733-7
Interferon beta Ab [Measurement] in Serum or Plasma
Trial
Status Information
- Status
- TRIAL
Term Description
This term is intended to collate similar measurements for the LOINC SNOMED CT Collaboration in an ontological view. Additionally, it can be used to communicate a laboratory order, either alone or in combination with specimen or other information in the order. It may NOT be used to report back the measured patient value. https://lo.inc/ce2mb6
Part Descriptions
LP18172-4 Interferon.beta
Beta interferon is a recombinant protein which is chemically identical to or similar to endogenous interferon beta with antiviral and anti-tumor activities. Endogenous interferons beta are cytokines produced by nucleated cells (predominantly natural killer cells) upon exposure to live or inactivated virus, double-stranded RNA or bacterial products. These agents bind to specific cell-surface receptors, resulting in the transcription and translation of genes with an interferon-specific response element. The proteins so produced mediate many complex effects, including antiviral (the most important being inhibition of viral protein synthesis), antiproliferative and immune modulating effects. The recombinant therapeutic forms of interferon beta are interferon beta 1-a and interferon beta 1-b.
Source: National Cancer Institute,
Beta interferon
LP38708-1 Interferon.beta Ab
Highly elevated levels of neutralizing antibodies (NAbs >1:100) to interferon-beta used as therapy in patients with Multiple Sclerosis have been reported to correlate with predictable loss of interferon-beta bioactivity. In patients with elevated NAb levels from >1:20 to <1:100, interferon-beta bioactivity may still be present, but does not necessarily correlate to the exact NAb titer, and continued patient monitoring may be warranted. There is no apparent loss of interferon-beta bioactivity in patients who test positive in the binding antibody assay, but
negative for NAbs; however, continued patient monitoring may also be warranted in this instance as well.
Source: Quest Diagnostics Inc.,
Interferon-beta 1a (IFNB-1a) Antibody
LP447904-6 {Measurement}
{Measurement} is a Property grouper part used to collate terms with comparable measurement-related properties. It encompasses the following LOINC Properties: ACnc, AFr, ARat, CAct, CCnc, CCnt, CRat, CSub, EntLen, LaCnc, LnCnc, Mass, MCnc, MCnt, MRat, MRto, MSCnc, MSRat, Naric, NCnc, NFr, Prctl, PrThr, Ratio, SatFr, SCnc, SCnt, SRat, SRto, Sub, ThreshNum, Titr, and TmMCn.
Source: Regenstrief LOINC
LOINC Names Get Info
- Fully-Specified Name
- Interferon.beta Ab:
{Measurement}: -: Ser/Plas: -: - Long Common Name
- Interferon beta Ab [Measurement] in Serum or Plasma
- Short Name
- IFN-B Ab Msmt SerPl
- Display Name
- Interferon beta Ab [Measurement]
- Consumer Name Alpha Get Info
- Interferon beta antibody, Blood
Part Model Get Info
Basic Attributes
- Class
- LABORDERS.ONTOLOGY
- Type
- Laboratory
- First Released
- Version 2.81
- Last Updated
- Version 2.81 (ADD)
- Order vs. Observation
- Order
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Interferon beta Anticuerpos: |
| fr-FR | French (France) | Interféron bêta Ac: |
| it-IT | Italian (Italy) | Interferone.beta Ab: Synonyms: anticorpo Codici richieste di laboratorio Interferone beta LABORDERS.ONTOLOGY Misurazione Plasma Siero Siero o Plasma |
| pl-PL | Polish (Poland) | Interferon.beta Ab: Synonyms: IFN-beta Przeciwciała do interferonu beta |
| zh-CN | Chinese (China) | 干扰素.beta 抗体: Synonyms: {测量}; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://