Version 2.72

1091-8K Ab [Presence] in Serum or Plasma from Blood product unitActive

Part Description

LP14926-7   K
Kell is highly polymorphic. It has two major codominant alleles, k and K, which result from a SNP (698C→T), and the corresponding k and K antigens differ by a single amino acid change (T193M). Mostly IgG antibodies, so IgM is uncommon. Anti-K does not bind complement. If hemolysis does occur, it is extravascular in nature. Anti-K can cause a severe hemolytic transfusion reaction and severe fetal anemia. In the RBC membrane, the Kell glycoprotein is covalently linked to the XK protein, a multipass membrane protein thought to have a role in transport. In the absence of XK, a condition called McLeod syndrome, Kell antigens are only weakly expressed and the RBCs are abnormal with spiky projections (acanthocytosis). Systemic findings include muscular dystrophy, cardiomyopathy, psychiatric disturbances, and neurological defects, such as loss of reflexes and movement disorders. The frequency of K antigens is 2% in Blacks, 9% in Caucasians, up to 25% in Arabs populations. Beck L, Blood groups and red cell antigens. NCBI Bookself [Internet Book], 2005. Source: National Library of Medicine, K

Fully-Specified Name

K Ab

Additional Names

Short Name
K Ab SerPl BPU Ql
Display Name
K Ab Ql (S/P BPU)
Consumer Name Alpha
K antibody, Blood Product Unit

Basic Attributes

First Released
Version 1.0
Last Updated
Version 2.56
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation

Language Variants Get Info

zh-CNChinese (China)
K 抗体:存在情况或阈值:时间点:血清/血浆^血液制品单位:序数型:
nl-NLDutch (Netherlands)
K As:aanwezigheid:moment:serum of plasma^bloedproducteenheid:ordinaal:
fr-BEFrench (Belgium)
K Ac:PrThr:Temps ponctuel:Sérum/Plasma^Unité de produit sanguin:Ordinal:
fr-CAFrench (Canada)
K , Ac:Présence-Seuil:Temps ponctuel:Sérum/Plasma^Unité de produit sanguin:Ordinal:
fr-FRFrench (France)
KEL1 (K) anticorps:Présence/Seuil:Ponctuel:Sérum/Plasma/Poche:Qualitatif:
it-ITItalian (Italy)
K Ab:PrThr:Pt:Siero/Plasma^Unità prodotto sangue:Ord:
ko-KRKorean (Korea, Republic of)
k 항체:임의농도:검사시점:혈청/혈장^혈액제제단위:순위척도:
pt-BRPortuguese (Brazil)
K Ac:ACnc:Pt:Sor/Plas^bolsa de sangue:Ord:
ru-RURussian (Russian Federation)
K Ат:PrThr:ТчкВрм:Сыв/Плаз^КПЕ:Пор:
es-ARSpanish (Argentina)
[anticuerpo anti - ] K [Ac]:concentración arbitraria:punto en el tiempo:suero/plasma^unidad de hemoderivado:ordinal:
es-MXSpanish (Mexico)
K Ab:Presencia o umbral:Punto temporal:Suero o plasma ^ Unidad de hemoderivado:Ordinal:
es-ESSpanish (Spain)
K Anticuerpos:PrThr:Punto temporal:Suero o Plasma^Unidad de hemoderivado:Ord:
tr-TRTurkish (Turkey)
K Ab:MevcEşik:Zmlı:Ser/Plaz^KanÜrÜ:Srl:

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