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Status Information

Status
TRIAL

Term Description

This term is intended to collate similar measurements for the LOINC SNOMED CT Collaboration in an ontological view. Additionally, it can be used to communicate a laboratory order, either alone or in combination with specimen or other information in the order. It may NOT be used to report back the measured patient value. https://lo.inc/ce2mb6

Part Descriptions

LP447904-6   {Measurement}
{Measurement} is a Property grouper part used to collate terms with comparable measurement-related properties. It encompasses the following LOINC Properties: ACnc, AFr, ARat, CAct, CCnc, CCnt, CRat, CSub, EntLen, LaCnc, LnCnc, Mass, MCnc, MCnt, MRat, MRto, MSCnc, MSRat, Naric, NCnc, NFr, Prctl, PrThr, Ratio, SatFr, SCnc, SCnt, SRat, SRto, Sub, ThreshNum, Titr, and TmMCn. Source: Regenstrief LOINC

LP71719-6   U1 small nuclear ribonucleoprotein A
U1 small nuclear ribonucleoprotein particle (U1 snRNP) is an RNA-protein complex that is composed of ten proteins: U1-70kD, U1A, U1C and seven Smith antigen (Sm) proteins. The U1 snRNP complex is responsible for pre-mRNA processing. Autoantibodies to different components of the U1 snRNP complex are associated with autoimmune conditions including systemic lupus erythematosus (SLE) and mixed connective tissue disorders (MCTD), which includes systemic sclerosis. The pattern of autoantibodies present in an individual patient may help distinguish between different connective tissue disorders. For example, patients with anti-U1A and anti-U1C IgM antibodies are more likely to have SLE than MCTD. PMID: 24158973 In addition, there is some evidence that specific antibody patterns are associated with specific symptoms. For example, among patients with SLE, the combination of anti-U1-70kD, anti-U1A and anti-U1C correlates with Raynaud's phenomenon, while anti-U1-70kD and anti-U1A (without anti-U1C) correlate with leukopenia. Another study found an association between the number of specific positive antibodies within the anti-U1 snRNP (rather than the presence of particular markers) and certain clinical features. For example, patients with three or more positive autoantibodies were more likely to have features of systemic sclerosis and less likely to have renal disease compared to patients with fewer types of antibodies. PMID: 20015915 Source: Regenstrief LOINC, PMID: 24158973

LOINC Names Get Info

Fully-Specified Name
U1 small nuclear ribonucleoprotein A Ab:{Measurement}:-:Ser:-:
Long Common Name
U1 small nuclear ribonucleoprotein A Ab [Measurement] in Serum
Short Name
U1 snRNP-A Ab Msmt Ser
Display Name
U1 small nuclear ribonucleoprotein A Ab (S) [Measurement]
Consumer Name Alpha Get Info
U1 Small Nuclear Ribonucleoprotein A antibody, Blood

Part Model Get Info

  • Component
    U1 small nuclear ribonucleoprotein A Ab
    LP71701-4
    • Analyte
      U1 small nuclear ribonucleoprotein A Ab
      LP71701-4
      • Component Numerator
        U1 small nuclear ribonucleoprotein A Ab
        LP71701-4
        • Component Numerator Core
          U1 small nuclear ribonucleoprotein A
          LP71719-6
        • Component Numerator Core Suffix
          Ab
          LP20667-9
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    {Measurement}
    LP447904-6
  • Time
    -
    LP70420-2
  • System
    Ser
    LP7567-3
    • System Core
      Ser
      LP7567-3
    • Super System
      NULL
       
  • Scale
    -
    LP7747-1
  • Method
    NULL
     

Basic Attributes

Class
LABORDERS.ONTOLOGY
Type
Laboratory
First Released
Version 2.81
Last Updated
Version 2.81 (ADD)
Order vs. Observation
Order

Language Variants Get Info

TagLanguageTranslation
es-ESSpanish (Spain)U1 ribonucleoproteína nuclear pequeña A Anticuerpos:Medición:-:Suero:-:
fr-FRFrench (France)U1 RNP A Ac:{Mesure}:-:Sérum:-:
it-ITItalian (Italy)U1, piccola ribonucleoproteina nucleare A Ab:{Misurazione}:-:Siero:-:
Synonyms: anticorpo Codici richieste di laboratorio LABORDERS.ONTOLOGY Misurazione Piccola ribonucleoproteina nucleare U1 Piccola ribonucleoproteina nucleare U1 A Siero
pl-PLPolish (Poland)U1 mała jądrowa rybonukleoproteina A Ab:{Oznaczenie}:-:surowica:-:
Synonyms: Mała rybonukleoproteina jądrowa U1 Przeciwciała do bogatej w urydynę małej jądrowej nukleoproteiny A U1-snRNP A
zh-CNChinese (China)U1 小细胞核核糖核蛋白 A 抗体:{检测}:-:血清:-:
Synonyms: {测量};{测定};{检测结果};{测量结果};{测定结果} A 型 A 型抗体 Ab;自身抗体 RNP snRNP U1 RNP A;U1 snRNP A;U1 小细胞核核糖核蛋白 A;U1 small nuclear ribonucleoprotein A;U1RNP A U1 RNP;U1 snRNP;U1 小细胞核核糖核蛋白;U1 small nuclear ribonucleoprotein;U1RNP 多重;多重型;多重标尺类型;多重精度类型 实验室检验项目医嘱类;检验项目医嘱;检验项目申请;化验项目申请 小分子核糖核蛋白体 小分子细胞核核糖核蛋白 小核核糖核蛋白（Small nuclear ribonucleoprotein，snRNP） 核;胞核 核内小核糖核蛋白 核微小核糖核蛋白 核糖核蛋白（Ribonucleoprotein，Ribonuclear protein，RNP） 核蛋白 检验申请.本体;实验室检验医嘱.本体

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=109116-4