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Status
TRIAL

Term Description

This term is intended to collate similar measurements for the LOINC SNOMED CT Collaboration in an ontological view. Additionally, it can be used to communicate a laboratory order, either alone or in combination with specimen or other information in the order. It may NOT be used to report back the measured patient value. https://lo.inc/ce2mb6

Part Descriptions

LP14697-4   Thyroglobulin
Thyroglobulin (Tg) is a protein produced by and used entirely within the thyroid gland. Thyroglobulin is used by the thyroid gland to produce the thyroid hormones thyroxine (T4) and triiodothyronine (T3). Thyroglobulin is stored in the thyroid in follicle cysts surrounded by colloid cells. Via a reaction with the enzyme thyroperoxidase, iodine is covalently bound to tyrosine residues in thyroglobulin molecules, forming monoiodotyrosine (MIT) and diiodotyrosine (DIT). Thyroxine is produced by linking two moieties of DIT. Combining one particle of MIT and one particle of DIT produces triiodothyronine. Proteases in lysosomes digest iodinated thyroglobulin, releasing T3 and T4. Thyroglobulin levels in the blood can be used as a tumor marker for certain kinds of thyroid cancer. Thyroglobulin levels in the blood can also be elevated in cases of Graves Disease. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Thyroglobulin (Wikipedia)

LP14697-4   Thyroglobulin
Thyroglobulin (Tg) is a glycoprotein homodimer produced by the thyroid gland. It is important in the synthesis of thyroxine and triiodothyronine, and is where the inactive forms of thyroid hormone and iodine are stored. Mutations in the Tg gene cause thyroid dyshormonogenesis resulting in goiter, and can be associated with moderate to severe congenital hypothyroidism. Polymorphisms in the Tg gene are associated with susceptibility to autoimmune thyroid diseases such as Graves disease or Hashimoto thyroiditis. [NCBI Gene ID:7038] Tg is an established tumor marker used in the diagnosis of differentiated thyroid carcinoma. PMID: 9543128 Source: Regenstrief LOINC

LP39996-1   Thyroglobulin Ab
Circulating immunoglobulins directed against thyroglobulin are commonly present in patients with autoimmune (Hashimoto) thyroiditis and, to a lesser extent, Graves disease. Thyroglobulin is a 660-kd protein precursor of thyroid hormones. Thyroglobulin antibodies are present in the sera of approximately 70% of patients with autoimmune thyroiditis. The principal use of the test is to confirm that a patient's diffuse goiter and/or hypothyroidism is due to autoimmune thyroiditis. The test may also help distinguish Graves disease from toxic nodular goiter. Although thyroglobulin antibodies are present less often than thyroid microsomal antibodies (eg, thyroid peroxidase antibodies, anti-TPO) in patients with autoimmune thyroid diseases, screening fro both immunoglobulins increases diagnostic sensitivity. Thyroglobulin antibodies may be detected in individuals without clinically significant thyroid disease. They do not define the patient's thyroid functional status. Source: Quest Diagnostics Inc., Thyroglobulin antibodies

LP447904-6   {Measurement}
{Measurement} is a Property grouper part used to collate terms with comparable measurement-related properties. It encompasses the following LOINC Properties: ACnc, AFr, ARat, CAct, CCnc, CCnt, CRat, CSub, EntLen, LaCnc, LnCnc, Mass, MCnc, MCnt, MRat, MRto, MSCnc, MSRat, Naric, NCnc, NFr, Prctl, PrThr, Ratio, SatFr, SCnc, SCnt, SRat, SRto, Sub, ThreshNum, Titr, and TmMCn. Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Thyroglobulin Ab:{Measurement}:-:Ser:-:
Long Common Name
Thyroglobulin Ab [Measurement] in Serum
Short Name
Thyroglob Ab Msmt Ser
Display Name
Thyroglobulin Ab (S) [Measurement]
Consumer Name Alpha Get Info
Thyroglobulin antibody, Blood

Part Model Get Info

  • Component
    Thyroglobulin Ab
    LP39996-1
    • Analyte
      Thyroglobulin Ab
      LP39996-1
      • Component Numerator
        Thyroglobulin Ab
        LP39996-1
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    {Measurement}
    LP447904-6
  • Time
    -
    LP70420-2
  • System
    Ser
    LP7567-3
    • System Core
      Ser
      LP7567-3
    • Super System
      NULL
       
  • Scale
    -
    LP7747-1
  • Method
    NULL
     

Basic Attributes

Class
LABORDERS.ONTOLOGY
Type
Laboratory
First Released
Version 2.81
Last Updated
Version 2.81 (ADD)
Order vs. Observation
Order

Language Variants Get Info

TagLanguageTranslation
es-ESSpanish (Spain)Tiroglobulina Anticuerpos:Medición:-:Suero:-:
fr-FRFrench (France)Thyroglobuline Ac:{Mesure}:-:Sérum:-:
it-ITItalian (Italy)Tireoglobulina Ab:{Misurazione}:-:Siero:-:
Synonyms: anticorpo Codici richieste di laboratorio LABORDERS.ONTOLOGY Misurazione Siero
pl-PLPolish (Poland)Tyreoglobulina Ab:{Oznaczenie}:-:surowica:-:
zh-CNChinese (China)甲状腺球蛋白 抗体:{检测}:-:血清:-:
Synonyms: {测量};{测定};{检测结果};{测量结果};{测定结果} Ab;自身抗体 TG;甲状球蛋白;甲状腺球朊;甲状腺球蛋白（Thyroglobulin，TG，Tg）;甲状腺球蛋白特异性 TgAbs 多重;多重型;多重标尺类型;多重精度类型 实验室检验项目医嘱类;检验项目医嘱;检验项目申请;化验项目申请 抗甲状腺球蛋白 检验申请.本体;实验室检验医嘱.本体 甲状腺球蛋白 Ab

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=110119-5