Version 2.72

11053-6Lactate dehydrogenase [Enzymatic activity/volume] in Red Blood CellsActive

Part Descriptions

LP15033-1   Lactate dehydrogenase
Lactate dehydrogenase (LDH) is an enzyme (EC present in a wide variety of organisms, including plants and animals. It catalyses the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+. As it can also catalyze the oxidation of hydroxybutyrate, it is occasionally called hydroxybutyrate dehydrogenase (HBD). Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, D-lactate (Wikipedia)

LP15033-1   Lactate dehydrogenase
Lactate dehydrogenase (LDH, or also called LD) is an oxidoreductase (LD: EC and is the most important clinically of several dehydrogenases occurring in human serum. LDH catalyses the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD. When disease, injury, or toxic material damages tissues, cells release LDH into the bloodstream. Since LDH is a fairly stable enzyme, it has been widely used to evaluate the presence of damage and toxicity of tissue and cells. LDH is cytoplasmic in its cellular location and in any one tissue is composed of one or two of five possible isoenzymes. While many of its clinical applications involve quantification of one or more specific serum isoenzymes, an estimate of total LDH is usually required. Lactate dehydrogenase catalyzes the reversible reaction: L-lactate + NAD <--> pyruvate + NADH. Testing methods either measure the increase in NADH produced in the lactate-to-pyruvate reaction or the decrease in NADH produced in the pyruvate-to-lactate reaction. [PMID:3882046]. Reference ranges are highly method dependent. The pyruvate-to-lactate reaction is preferred theoretically because the equilibrium constant is large and the rate for any amount of enzyme is 2-3 times faster, thus smaller sample and shorter observation periods are needed. Disadvantages of the pyruvate-to-lactate reaction are loss of linearity as compared with the lactate-to-pyruvate reaction, and greater substrate inhibition of the enzyme. [Tietz Fourth Edition] Source: Regenstrief LOINC

Fully-Specified Name

Lactate dehydrogenase

Additional Names

Short Name
Display Name
LDH (RBC) [Catalytic activity/Vol]
Consumer Name Alpha
Lactate Dehydrogenase (LDH), Red blood cells

Basic Attributes

First Released
Version 1.0j-a
Last Updated
Version 2.44
Order vs. Observation

Language Variants Get Info

zh-CNChinese (China)
nl-NLDutch (Netherlands)
lactaatdehydrogenase:enzymatische activiteit/volume:moment:erytrocyten:kwantitatief:
et-EEEstonian (Estonia)
Laktaadi dehüdrogenaas:CCnc:Pt:RBC:Qn:
fr-BEFrench (Belgium)
Lactate déshydrogénase:Concentration catalytique:Temps ponctuel:GR:Quantitatif:
fr-CAFrench (Canada)
Lactate déshydrogénase:Concentration catalytique:Temps ponctuel:GR:Quantitatif:
fr-FRFrench (France)
Lactate déhydrogénase:Catalytique/Volume:Ponctuel:Érythrocytes:Numérique:
de-DEGerman (Germany)
Lactatdehydrogenase:Katalytische Konzentration:Zeitpunkt:Erythrozyten:Quantitativ:
el-GRGreek (Greece)
Γαλακτική αφυδρογονάση:Καταλυτική Συγκέντρωση:Χρονική στιγμή:Ερυθρά αιμοσφαίρια:Ποσοτική:
it-ITItalian (Italy)
Lattato deidrogenasi:CCnC:Pt:RBC:Qn:
ko-KRKorean (Korea, Republic of)
젖산 탈수소효소:촉매농도:검사시점:적혈구:정량:
pl-PLPolish (Poland)
Dehydrogenaza mleczanowa:Stężenie katalityczne:Punkt w czasie:Krwinki czerwone RBC:ilościowy:
pt-BRPortuguese (Brazil)
Desidrogenase Láctica:CCnc:Pt:Eritroc:Qn:
ru-RURussian (Russian Federation)
es-ARSpanish (Argentina)
lactato deshidrogenasa:concentración catalítica:punto en el tiempo:eritrocitos:cuantitativo:
es-MXSpanish (Mexico)
Lactato deshidrogenasa:Concentración catalítica:Punto temporal:Eritrocitos:Cuantitativo:
es-ESSpanish (Spain)
Lactato deshidrogenasa:Concentración Catalítica:Punto temporal:Glóbulos rojos:Qn:
tr-TRTurkish (Turkey)
Laktat dehidrojenaz:KtlKons:Zmlı:Eritrosit:Kant:

Example Units

Unit Source
U/mL{RBCs} Example UCUM Units

LOINC FHIR® API Example - CodeSystem Request Get Info