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Status
TRIAL

Term Description

This term is intended to collate similar measurements for the LOINC SNOMED CT Collaboration in an ontological view. Additionally, it can be used to communicate a laboratory order, either alone or in combination with specimen or other information in the order. It may NOT be used to report back the measured patient value. https://lo.inc/ce2mb6

Part Descriptions

LP39188-5   Aquaporin 4 water channel Ab.IgG
The water channel aquaporin 4 (AQP4) receptor regulates the water homeostasis in the central nervous system (CNS). Autoantibodies to the AQP4 receptor bind to the receptor and cause neuromyelitis optica (NMO) which is an idiopathic, severe, demyelinating disease of the CNS that primarily affects the optic nerve and spinal cord. Before the discovery of the AQP4 receptor antibody NMO was often misdiagnosed as a variant of multiple sclerosis (MS). With improved clinical laboratory tests and distinct immunological and pathological attributes the two diseases are less often confused. Distinguishing MS and NMO is especially important because they have different treatments. Treatment for NMO includes corticosteroids and plasmapheresis; typical medications used to treat MS, such as beta-interferon and glatiramer acetate are not effective against NMO. During the disease process, the aquaporin 4 receptor antibody binds to the aquaporin 4 receptor initiating the activation of complement, inflammatory demyelination and necrosis. Eighty to ninety percent of patients with NMO experience recurrent episodes of optic neuritis and myelitis. Many patients with NMO also have other autoimmune diseases including thyroiditis, systemic lupus erythematosus
and Sjogren's syndrome. PMID: 17706564 Detection of APQ4-IgG is indicative of a relapsing disease. Immediate treatment with immunosuppressive drugs reduces the frequency and disability of future attacks. http://labmed.ucsf.edu/labmanual/db/dataall/tests/1424.html Source: Regenstrief LOINC

LP447904-6   {Measurement}
{Measurement} is a Property grouper part used to collate terms with comparable measurement-related properties. It encompasses the following LOINC Properties: ACnc, AFr, ARat, CAct, CCnc, CCnt, CRat, CSub, EntLen, LaCnc, LnCnc, Mass, MCnc, MCnt, MRat, MRto, MSCnc, MSRat, Naric, NCnc, NFr, Prctl, PrThr, Ratio, SatFr, SCnc, SCnt, SRat, SRto, Sub, ThreshNum, Titr, and TmMCn. Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Aquaporin 4 water channel Ab.IgG:{Measurement}:-:CSF:-:
Long Common Name
Aquaporin 4 water channel IgG Ab [Measurement] in Cerebrospinal Fluid
Short Name
AQP4 H2O channel IgG Msmt CSF
Display Name
Aquaporin 4 water channel IgG (CSF) [Measurement]
Consumer Name Alpha Get Info
Aquaporin 4 water channel IgG antibody, Spinal fluid

Part Model Get Info

  • Component
    Aquaporin 4 water channel Ab.IgG
    LP39188-5
    • Analyte
      Aquaporin 4 water channel Ab.IgG
      LP39188-5
      • Component Numerator
        Aquaporin 4 water channel Ab.IgG
        LP39188-5
        • Component Numerator Core
          Aquaporin 4 water channel
          LP102619-6
        • Component Numerator Core Suffix
          Ab.IgG
          LP32401-9
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    {Measurement}
    LP447904-6
  • Time
    -
    LP70420-2
  • System
    CSF
    LP7156-5
    • System Core
      CSF
      LP7156-5
    • Super System
      NULL
       
  • Scale
    -
    LP7747-1
  • Method
    NULL
     

Basic Attributes

Class
LABORDERS.ONTOLOGY
Type
Laboratory
First Released
Version 2.81
Last Updated
Version 2.83 (MIN)
Order vs. Observation
Order

Language Variants Get Info

TagLanguageTranslation
es-ESSpanish (Spain)Receptor de Acuaporina 4 IgG:Medición:-:Líquido Cefalorraquideo:-:
fr-FRFrench (France)Aquaporine 4 récepteur Ac IgG:{Mesure}:-:Liquide céphalorachidien:-:
it-ITItalian (Italy)Acquaporina 4, canale idrico Ab.IgG:{Misurazione}:-:LCS:-:
Synonyms: anticorpi IgG anticorpo Canale idrico dell''acquaporina 4 Codici richieste di laboratorio LABORDERS.ONTOLOGY Liquido cerebrospinale Misurazione
zh-CNChinese (China)水通道蛋白 4 受体 抗体.IgG:{检测}:-:脑脊液:-:
Synonyms: {测量};{测定};{检测结果};{测量结果};{测定结果} Ab.IgG;IgG;抗体 IgG Ab;自身抗体 CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 Devic 氏综合征 IgG Devic 综合征 IgG Devic氏综合征 Ab.IgG Devic氏综合征抗体.IgG Devic综合征 Ab.IgG Devic综合征抗体.IgG H2O NMO Ab.IgG NMO 抗体.IgG 免疫球蛋白 G 多重;多重型;多重标尺类型;多重精度类型 实验室检验项目医嘱类;检验项目医嘱;检验项目申请;化验项目申请 检验申请.本体;实验室检验医嘱.本体 脊液 脊髓液 脑脊液（Cerebral spinal fluid，CSF） 脑脊髓液 视神经脊髓炎 Ab.IgG 视神经脊髓炎 IgG

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=110868-7