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Status Information

Status
TRIAL

Term Description

This term is intended to collate similar measurements for the LOINC SNOMED CT Collaboration in an ontological view. Additionally, it can be used to communicate a laboratory order, either alone or in combination with specimen or other information in the order. It may NOT be used to report back the measured patient value. https://lo.inc/ce2mb6

Part Descriptions

LP18489-2   Glutamate decarboxylase 65
Glutamate decarboxylase 65 (GAD65) antibody is useful to diagnose insulin dependent diabetes mellitus (IDDM, Type I diabetes), to assess the risk for developing IDDM, to predict the onset of IDDM and the risk of developing related endocrine disorders such as thyroiditis. Before clinical onset, Type I diabetes is characterized by lymphocytic infiltration of the islet cells and by circulating autoantibodies against a variety of islet cell antigens including GAD-65, IA-2 (a tyrosine phosphatase-like protein), and insulin (IAA). GAD has two isoforms, GAD65 and GAD67, which are highly homologous but found in distinct subsets of patients. PMID: 7532143 GAD65 antibodies are specific to patients with insulin-dependent diabetes. The presence of GAD antibodies in a patient recently diagnosed with diabetes indicates a high risk of requiring insulin within three years. PMID: 11114103 GAD67 is important to the maturation of perisomatic innervation.( http://www.sciencedirect.com/science/article/pii/S0896627307003728) GAD65 are also associated with paraneoplastic neurologic syndrome (PNS) which is an autoimmune disorder that is manifested by progressive neurological syndromes of any combination of the central, peripheral and autonomic nervous systems. In addition, the different PNS antibodies are associated with certain cancers and can assist in identifying where an unknown tumor is located. PMID: 22412264 Glutamic acid decarboxylase 65 antibody are associated with stiff person syndrome, cerebellar ataxia encephalitis and other neurological diseases. PMID: 22405456 Source: Regenstrief LOINC

LP447904-6   {Measurement}
{Measurement} is a Property grouper part used to collate terms with comparable measurement-related properties. It encompasses the following LOINC Properties: ACnc, AFr, ARat, CAct, CCnc, CCnt, CRat, CSub, EntLen, LaCnc, LnCnc, Mass, MCnc, MCnt, MRat, MRto, MSCnc, MSRat, Naric, NCnc, NFr, Prctl, PrThr, Ratio, SatFr, SCnc, SCnt, SRat, SRto, Sub, ThreshNum, Titr, and TmMCn. Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Glutamate decarboxylase 65 Ab:{Measurement}:-:Ser:-:
Long Common Name
Glutamate decarboxylase 65 Ab [Measurement] in Serum
Short Name
GAD65 Ab Msmt Ser
Display Name
Glutamate decarboxylase 65 Ab (S) [Measurement]
Consumer Name Alpha Get Info
Glutamate decarboxylase 65 antibody, Blood

Part Model Get Info

  • Component
    Glutamate decarboxylase 65 Ab
    LP38251-2
    • Analyte
      Glutamate decarboxylase 65 Ab
      LP38251-2
      • Component Numerator
        Glutamate decarboxylase 65 Ab
        LP38251-2
        • Component Numerator Core
          Glutamate decarboxylase 65
          LP18489-2
        • Component Numerator Core Suffix
          Ab
          LP20667-9
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    {Measurement}
    LP447904-6
  • Time
    -
    LP70420-2
  • System
    Ser
    LP7567-3
    • System Core
      Ser
      LP7567-3
    • Super System
      NULL
       
  • Scale
    -
    LP7747-1
  • Method
    NULL
     

Basic Attributes

Class
LABORDERS.ONTOLOGY
Type
Laboratory
First Released
Version 2.81
Last Updated
Version 2.81 (ADD)
Order vs. Observation
Order

Language Variants Get Info

TagLanguageTranslation
es-ESSpanish (Spain)Glutamato decarboxilasa 65 Anticuerpos:Medición:-:Suero:-:
fr-FRFrench (France)Glutamate décarboxylase 65 Ac:{Mesure}:-:Sérum:-:
it-ITItalian (Italy)Glutammato decarbossilasi 65 Ab:{Misurazione}:-:Siero:-:
Synonyms: anticorpo Codici richieste di laboratorio GAD65 LABORDERS.ONTOLOGY Misurazione Siero
pl-PLPolish (Poland)Dekarboksylaza glutaminianu 65 Ab:{Oznaczenie}:-:surowica:-:
Synonyms: Dekarboksylaza kwasu glutaminowego o masie 65 kDa;GAD 65 kDa Dekarboksylaza kwasu glutaminowego;GAD Przeciwciała do dekarboksylazy glutaminianowej 65
zh-CNChinese (China)谷氨酸脱羧酶-65 抗体:{检测}:-:血清:-:
Synonyms: {测量};{测定};{检测结果};{测量结果};{测定结果} Ab;自身抗体 GAD65;GAD-65;谷氨酸脱羧酶 65;谷氨酸脱羧酶 65（Glutamate Decarboxylase 65，GAD65，Glutamic acid decarboxylase-65，GAD-65） GADA Glu 多重;多重型;多重标尺类型;多重精度类型 实验室检验项目医嘱类;检验项目医嘱;检验项目申请;化验项目申请 检验申请.本体;实验室检验医嘱.本体 谷氨酸脱羧酶 65 Ab 谷氨酸脱羧酶 65 抗体 谷氨酸脱羧酶-65 Ab 麸胺酸去羧酶;麸胺酸去羧基酶;麸氨酸去羧基酶;GAD

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=111335-6