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Part Description

LP14239-5   Influenza virus A
Influenza viruses, from the family Orthomyxoviridae, are enveloped negative-strand RNA viruses with segmented genomes containing seven to eight gene segments. Of the five genera in the family, only influenza A virus (IAV), influenza B and C are medically relevant to humans. Aquatic birds harboring avian IAV are the likely natural reservoir for all known IAV subtypes and are probably the original source of all human pandemic IAV strains. IAV maintained in wild birds have been associated with stable host switch events to novel hosts, including most often to domestic poultry but also to horses, swine, toothed whales and humans. The influenza virus life cycle begins with the binding of viral HA to host cell receptors. Endocytosis and HA-mediated fusion of the viral and cellular membranes occurs. Viral ribonucleoprotein complexes are released into the cytoplasm, travel to the nucleus, then are replicated and transcribed by the viral polymerase complex. The new viruses are formed and bud when the newly formed ribonucleicprotein complexes and structural proteins reach the plasma membrane. Further research is needed to better understand how IAVs switch hosts and the viral genetic changes that underlie human adaptation. IAV causes respiratory infections in humans ranging from asymptomatic to fatal. Pandemics are attributed to "novel" viruses which possess a viral hemagglutinin (HA) to which humans do not have immunity. PMID: 20542248 ] PMID: 25812763
Influenza viruses A and B are single-stranded RNA enveloped viruses belonging to the Orthomyxoviridae family. The symptoms of infection of Influenza A and B include fever, cough, sore throat, rhinorrhea, nasal congestion, headache, myalgia and malaise. Some patients may experience gastrointestinal symptoms including watery diarrhea, vomiting and abdominal pain. The influenza viruses spread rapidly in enclosed spaces with a documented rate of infection of 70% following a common source of exposure. Infection occurs in the respiratory epithelium in both the upper and lower respiratory tract, and the virus can be found in many specimen types, including nasal aspirates, nasal or nasopharyngeal swabs, throat swabs, sputum and tracheal aspirates. When infection rates reach epidemic proportions, hospitalization of children and elderly patients rises as does the mortality rates of elderly patients.(Manual of Clinical Microbiology, 11th edition, James H. Jorgensen; Karen C. Carroll; Guido Funke; Michael A Pfaller; Marie Louise Landry; Sandra S. Richter; David W. Warnock) Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Influenza virus A RNA:PrThr:Pt:Bronchoalveolar aspirate:Ord:Non-probe.amp.tar
Long Common Name
Influenza virus A RNA [Presence] in Bronchoalveolar aspirate by NAA with non-probe detection
Short Name
FLUAV RNA BAS Ql NAA+n-prb
Display Name
FLUAV RNA NAA+non-probe Ql (Bronchoalveolar aspirate)
Consumer Name Alpha Get Info
Influenza A (Flu A), Bronchoalveolar aspirate

Part Model Get Info

  • Component
    Influenza virus A RNA
    LP38646-3
    • Analyte
      Influenza virus A RNA
      LP38646-3
      • Component Numerator
        Influenza virus A RNA
        LP38646-3
        • Component Numerator Core
          Influenza virus A
          LP14239-5
        • Component Numerator Core Suffix
          RNA
          LP32423-3
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    PrThr
    LP217195-9
  • Time
    Pt
    LP6960-1
  • System
    Bronchoalveolar aspirate
    LP249657-0
    • System Core
      Bronchoalveolar aspirate
      LP249657-0
    • Super System
      NULL
       
  • Scale
    Ord
    LP7751-3
  • Method
    Non-probe.amp.tar
    LP208998-7

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.82
Last Updated
Version 2.82 (ADD)
Order vs. Observation
Both

Member of these Groups Get Info

LOINC GroupGroup Name
LG32757-3Influenza virus

Language Variants Get Info

TagLanguageTranslation
it-ITItalian (Italy)Influenza A, virus RNA:PrThr:Pt:Aspirato broncoalveolare:Ord:Non-sonda.amp.tar
Synonyms: Amplificazione target non basata su sonda Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA Virus dell''influenza Virus dell''influenza A

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=111560-9