112421-3

Beta aminoisobutyrate [Moles/volume] in Serum or Plasma by LC/MS/MS

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Part Descriptions

LP15432-5 Beta aminoisobutyrate
3-Aminoisobutyric acid is a product formed by the catabolism of thymine. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

LP15432-5 Beta aminoisobutyrate
Beta aminoisobutyric acid (BAIB) is a nonprotein amino acid that is an end product of pyrimidine metabolism. The R and S enantiomers (previously named D-(minus)-BAIB and L-plus-BAIB) are produced from thymine and L-valine, respectively. Under normal circumstances, urine contains predominantly R-BAIB (from thymine) because it is eliminated by filtration and tubular secretion, while plasma contains about 80% S-BAIB (from valine), which is reabsorbed in the kidneys. In patients with dihydropyrimidine dehydrogenase deficiency, thymine catabolism is decreased, which results in moderately decreased CSF concentration and markedly decreased plasma concentration of BAIB. On the other hand, urine BAIB is elevated despite decreased breakdown of thymine, which indicates that there must be cross-over in the thymine and valine degradation pathways. PMID: 14705962 Deficiency of D-beta-aminoisobutyrate:pyruvate aminotransferase (EC 2.6.1.40) , an enzyme that is involved in the catabolism R-BAIB, also results in elevated urine BAIB and is associated with hyperuricemia. [OMIM: 210100] Source: Regenstrief LOINC, PMID: 14705962

LOINC Names Get Info

Fully-Specified Name: Beta aminoisobutyrate:SCnc:Pt:Ser/Plas:Qn:LC/MS/MS
Long Common Name: Beta aminoisobutyrate [Moles/volume] in Serum or Plasma by LC/MS/MS
Short Name: B-AIB SerPl LC/MS/MS-sCnc
Display Name: Beta aminoisobutyrate LC/MS/MS [Moles/Vol]
Consumer Name Alpha Get Info: Beta aminoisobutyrate, Blood

Part Model Get Info

Component
Beta aminoisobutyrate
LP15432-5
- Analyte
  Beta aminoisobutyrate
  LP15432-5
  - Component Numerator
    Beta aminoisobutyrate
    LP15432-5
    - Component Numerator Core
      Beta aminoisobutyrate
      LP15432-5
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
SCnc
LP6860-3
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser/Plas
LP7576-4
- System Core
  Ser/Plas
  LP7576-4
- Super System
  NULL
Scale
Qn
LP7753-9
Method
LC/MS/MS
LP95062-3

Basic Attributes

Class: DRUG/TOX
Type: Laboratory
First Released: Version 2.82
Last Updated: Version 2.82 (ADD)
Order vs. Observation: Observation

Member of these Groups Get Info

LOINC Group	Group Name
LG52629-9	Beta aminoisobutyrate\|SCnc\|Pt\|ANYBldSerPl

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	β-αμινοϊσοβουτυρικό:SCnc:Pt:Ορός/Πλάσμα:Qn:LC/MS/MS Synonyms: DRUG/TOX LC/MS/MS Pt Qn SCnc β-αμινοϊσοβουτυρικό Ορός Ορός/Πλάσμα Πλάσμα
es-ES	Spanish (Spain)	Beta aminoisobutirato:Concentración de sustancia:Punto temporal:Suero o Plasma:Qn:LC/MS/MS Synonyms: Cuantitativo
et-EE	Estonian (Estonia)	Beetaaminoisobutüraat:SCnc:Pt:S/P:Qn:LC/MS/MS Synonyms: Aine kontsentratsioon Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-CA	French (Canada)	Bêta-aminoisobutyrate:Concentration de substance:Temps ponctuel:Sérum/Plasma:Quantitatif:LC/MS/MS
fr-FR	French (France)	Bêta aminoisobutyrate:Moles/Volume:Ponctuel:Sérum/Plasma:Numérique:LC/MS/MS
fr-BE	French (Belgium)	Béta-aminoisobutyrate:Concentration de substance:Temps ponctuel:Sérum/Plasma:Quantitatif:LC/MS/MS
it-IT	Italian (Italy)	Beta aminoisobutirrato:SCnc:Pt:Siero/Plasma:Qn:LC/MS/MS Synonyms: Concentrazione di Sostanza Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma
nl-NL	Dutch (Netherlands)	bèta-amino-isobutyraat:mol/volume:moment:serum of plasma:kwantitatief:LC/MS/MS
pl-PL	Polish (Poland)	Beta aminoizomaślan:stężenie molowe:punkt w czasie:surowica lub osocze:ilościowy:chromatografia cieczowa z tandemową spektrometrią mas (LC-MS/MS)
tr-TR	Turkish (Turkey)	Beta aminoizobütirat:SubKons:Zmlı:Ser/Plaz:Kant:LC/MS/MS
zh-CN	Chinese (China)	Beta 氨基异丁酸:物质的量浓度:时间点:血清/血浆:定量型:LC/MS/MS Synonyms: 3-氨基异丁酸;B-AIB;Beta-氨基异丁酸;β氨基异丁酸;β-氨基异丁酸 B Tandem Mass Spectrometry;MS/MS;串联质谱分析;串联质谱法;mass spectrometer;MS;质谱法;质谱分析;liquid chromatography;LC;液相色谱分析;Liquid Chromatography-Tandem Mass Spectrometry;liquid chromatography-MS/MS;LC-MS/MS;液相色谱分析-串联质谱分析法;液相色谱-串联质谱检测方法;液相色谱质谱联用技术;串联质谱快速分析 β 克分子浓度;克分子浓度(单位体积);摩尔浓度;摩尔浓度(单位体积);物质的量浓度(单位体积) 可用数量表示的;定量性;数值型;数量型;连续数值型标尺时刻;随机;随意;瞬间毒品毒品类药品类药物药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类药物类血清或血浆贝塔

Example Units

Unit	Source
nmol/mL	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.