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Term Description

The PDR confirms that this drug is best measured in whole blood.

Part Descriptions

LP15182-6   Tacrolimus
Tacrolimus (also known as FK-506 or Prograf) is a macrolide isolated from the culture broth of a strain of Streptomyces tsukubaensis. It has strong immunosuppressive properties and is commonly used to prevent allograft rejection in transplant recipients. One of its modes of action is to prevent T-lymphocyte activation. Source: National Library of Medicine, MeSH 2006

LP15182-6   Tacrolimus
Tacrolimus (also called FK-506 or fujimycin, Prograf, Advagraf, or Protopic) is amacrolide lactone, calcineurin inhibitor immunosuppresent used mainly after allogeneic organ transplant to lower the risk of organ rejection. It possesses strong immunosuppressive activity by preventing the activation by of T-lymphocytes in response to antigenic or mitogenic stimulation. Tacrolimus is also used in a topical preparation in the treatment of atopic dermatitis (eczema), severe refractory uveitis after bone marrow transplants, exacerbations of minimal change disease, TH2-mediated diseases such as Kimura's disease, and the skin condition vitiligo. There are potentially severe side effects from doses that are either too low or too high; inadequate tacrolimus concentrations may result in rejection of the transplanted organ, while high levels may lead to severe adverse effects includin nephrotoxicity, neurotoxicity, gastrointestinal disturbances, diabetogenesis, hypertension and malignant complications. [Wikipedia: Tacrolimus] Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Tacrolimus

Reference Information

TypeSourceReference
Mapping GuidanceRegenstrief HelpBld is the preferred specimen Mapper’s Guide for the Top 2000 plus LOINC Laboratory Observations

LOINC Names Get Info

Fully-Specified Name
Tacrolimus:MCnc:Pt:Bld:Qn:
Long Common Name
Tacrolimus [Mass/volume] in Blood
Short Name
Tacrolimus Bld-mCnc
Display Name
Tacrolimus (Bld) [Mass/Vol]
Consumer Name Alpha Get Info
Tacrolimus, Blood

Part Model Get Info

  • Component
    Tacrolimus
    LP15182-6
    • Analyte
      Tacrolimus
      LP15182-6
      • Component Numerator
        Tacrolimus
        LP15182-6
        • Component Numerator Core
          Tacrolimus
          LP15182-6
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    MCnc
    LP6827-2
  • Time
    Pt
    LP6960-1
  • System
    Bld
    LP7057-5
    • System Core
      Bld
      LP7057-5
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 1.0j-a
Last Updated
Version 2.73 (MIN)
Order vs. Observation
Both
Common Test Rank Get Info
228

Member of these Groups Get Info

LOINC GroupGroup Name
LG1025-8Tacrolimus|MCnc|Pt|ANYBldSerPl

Language Variants Get Info

TagLanguageTranslation
ar-JOArabic (Jordan)التاكروليماس " البروغراف " في الدم ( بتقنية الكتلة / الحجم )
cs-CZCzech (Czechia)Takrolimus:Hmotnostní koncentrace:Časový bod:Krev:Kvantitativní:
de-ATGerman (Austria)Synonyms: Tacrolimus
de-DEGerman (Germany)Tacrolimus:Massenkonzentration:Zeitpunkt:Blut:Quantitativ:
el-GRGreek (Greece)Τακρόλιμους:MCnc:Pt:Αίμα:Qn:
Synonyms: DRUG/TOX MCnc Pt Qn Αίμα Τακρόλιμους
es-ARSpanish (Argentina)tacrolimus:concentración de masa:punto en el tiempo:sangre:cuantitativo:
es-ESSpanish (Spain)Tacrolimus:Concentración de masa:Punto temporal:Sangre:Qn:
Synonyms: Cuantitativo
es-MXSpanish (Mexico)Tacrolimus:Concentración de masa:Punto temporal:Sangre:Cuantitativo:
et-EEEstonian (Estonia)Takroliimus:MCnc:Pt:B:Qn:
Synonyms: Juhuslik Kvantitatiivne Veri
fr-CAFrench (Canada)Tacrolimus:Concentration de masse:Temps ponctuel:Sang:Quantitatif:
fr-FRFrench (France)Tacrolimus:Masse/Volume:Ponctuel:Sang:Numérique:
fr-BEFrench (Belgium)Tacrolimus:Concentration de masse:Temps ponctuel:Sang:Quantitatif:
it-ITItalian (Italy)Tacrolimus:MCnc:Pt:Sangue:Qn:
Synonyms: Concentrazione di Massa FK-506 Livelli farmacologici e tossicologia Punto nel tempo (episodio) Sangue
ko-KRKorean (Korea, Republic Of)타크로리무스:질량농도:검사시점:전혈:정량:
nl-NLDutch (Netherlands)tacrolimus:massa/volume:moment:bloed:kwantitatief:
pt-BRPortuguese (Brazil)Tacrolimus:MCnc:Pt:SgTotal:Qn:
Synonyms: FK-506; Prograf; FK506; Mass concentration; Level; Point in time; Random; Blood; WB; Whole blood; Quantitative; QNT; Quant; Quan; Drugs; DRUG/TOXICOLOGY; DRUG/TOXICOLOGY
ru-RURussian (Russian Federation)Такролимус:МассКонц:ТчкВрм:Кр:Колич:
Synonyms: Количественный Кровь Массовая концентрация Точка во времени;Момент
tr-TRTurkish (Turkey)Takrolimus:KütlKons:Zmlı:Kan:Kant:
uk-UAUkrainian (Ukraine)Такролімус:Масова Концентрація:МоментЧасу:Кров:Кількісно:
Synonyms: Blood; DRUG/TOXICOLOGY; Drugs; FK506; FK-506; Fujimycin; Hecoria; L04AD02; Level; Mass concentration; Point in time; Prograf; Protopic; QNT; Quan; Quant; Quantitative; Random; UniversalLabOrders; WB; Whole blood
zh-CNChinese (China)他克莫司:质量浓度:时间点:全血:定量型:
Synonyms: 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 普乐可复 毒品 毒品类 水平;浓度;质量浓度(单位体积) 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类 血;血液

Example Units

UnitSource
ng/mLExample UCUM Units
ng/mLREGENSTRIEF
ug/LeCHN

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=11253-2