112740-6

Jo-1 extractable nuclear IgG Ab [Units/volume] in Serum by Immunoassay

Active

Part Description

LP16719-4 Jo-1 extractable nuclear
Aminoacyl-tRNA synthetases (ARS) are enzymes that link amino acids to tRNA molecules and therefore play a key role in protein synthesis. Each ARS is specific for a single amino acid. [NCBI Books: NBK22356] Autoantibodies to ARS are a hallmark of connective tissue diseases including anti-synthetase syndrome (ASS) and idiopathic inflammatory myopathies such as polymyositis (PM) and dermatomyositis (DM). ASS, PM and DM have overlapping features, including myositis, arthralgia, skin manifestations and interstitial lung disease. Antibodies to several specific ARS enzymes have been identified, including anti-histidyl (anti-Jo-1), anti-threonyl (anti-PL-7), anti-alanyl (anti-PL-12), anti-glycyl (anti-Ej), anti-isoleucyl (anti-Oj), anti-asparaginyl (anti-Ks), anti-phenylalanyl (anti-Zo), and anti-tyrosyl (anti-Ha). Different antibodies or patterns of antibodies have been associated with specific clinical features. Anti-Jo-1, anti-Ej, and anti-PL-7 antibodies are associated with myositis, including classic DM, clinically amyopathic DM (CADM) and PM. Anti-PL-12 alone is associated with CADM or interstitial lung disease (ILD). Anti-Ej and anti-PL-12 together are associated with CADM. Anti-Ks and anti-Oj are associated with ILD alone. PMID: 23573256 Anti-Ha and anti-Zo antibodies are the most recent autoantibodies to be identified in patients with symptoms of ASS. PMID: 17392287 Identifying the particular anti-ARS antibodies associated with an individual patient's disease may help guide treatment and predict clinical outcomes. Source: Regenstrief LOINC, PMID: 23573256

LOINC Names Get Info

Fully-Specified Name: Jo-1 extractable nuclear Ab.IgG:ACnc:Pt:Ser:Qn:IA
Long Common Name: Jo-1 extractable nuclear IgG Ab [Units/volume] in Serum by Immunoassay
Short Name: ENA Jo1 IgG Ser IA-aCnc
Display Name: Jo-1 extractable nuclear IgG IA Qn (S)
Consumer Name Alpha Get Info: Jo-1 extractable nuclear IgG antibody, Blood

Part Model Get Info

Component
Jo-1 extractable nuclear Ab.IgG
LP38742-0
- Analyte
  Jo-1 extractable nuclear Ab.IgG
  LP38742-0
  - Component Numerator
    Jo-1 extractable nuclear Ab.IgG
    LP38742-0
    - Component Numerator Core
      Jo-1 extractable nuclear
      LP16719-4
    - Component Numerator Core Suffix
      Ab.IgG
      LP32401-9
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
ACnc
LP6773-8
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser
LP7567-3
- System Core
  Ser
  LP7567-3
- Super System
  NULL
Scale
Qn
LP7753-9
Method
IA
LP217197-5

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.83
Last Updated: Version 2.83 (ADD)
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	εκχυλίσιμα πυρηνικά αντιγόνα Jo-1 Αντισώματα IgG:ACnc:Pt:Ορός:Qn:IA Synonyms: ACnc IA MICRO Pt Qn Ανοσοσφαιρίνη G Αντίσωμα Αντισώματα IgG Εκχυλίσιμα πυρηνικά εκχυλίσιμα πυρηνικά αντιγόνα Jo-1 Ορός Πυρηνικό
es-ES	Spanish (Spain)	Jo-1 IgG:Concentración arbitraria:Punto temporal:Suero:Qn:IA Synonyms: Cuantitativo
fr-CA	French (Canada)	Jo-1 nucléaire soluble, IgG:Concentration arbitraire:Temps ponctuel:Sérum:Quantitatif:IA
fr-BE	French (Belgium)	Jo-1 nucléaire soluble Anticorps. IgG:Concentration arbitraire:Temps ponctuel:Sérum:Quantitatif:IA Synonyms: Anticorps
fr-FR	French (France)	Jo-1 Ac IgG:Arbitraire/Volume:Ponctuel:Sérum:Numérique:Immunoanalyse
it-IT	Italian (Italy)	Jo-1, nucleare estraibile Ab.IgG:ACnc:Pt:Siero:Qn:IA Synonyms: anticorpi IgG anticorpo Concentrazione Arbitraria ENA Immunoassay Jo1 Microbiologia Punto nel tempo (episodio) Siero
nl-NL	Dutch (Netherlands)	jo-1 extraheerbaar nucleair As.IgG:eenheid/volume:moment:serum:kwantitatief:immunoassay Synonyms: antistof; antilichaam IA
pl-PL	Polish (Poland)	Jo-1 rozpuszczalny jądrowy Ab.IgG:stężenie w jednostkach umownych:punkt w czasie:surowica:ilościowy:metoda immunologiczna Synonyms: IgG Jo-1 rozpuszczalny jądrowy Przeciwciała do rozpuszczalnego antygenu jądrowego Przeciwciała do rozpuszczalnego jądrowego antygenu Jo-1 przeciwciała IgG Przeciwciała IgG do jądra komórkowego Przeciwciała IgG do rozpuszczalnego jądrowego antygenu Jo-1 Przeciwciała przeciwjądrowe
ru-RU	Russian (Russian Federation)	Jo-1 экстрагируемый ядерный Ат.IgG:ПроизвКонц:ТчкВрм:Сыв:Колич:IA Synonyms: Антитело Количественный Произвольная концентрация Сыворотка Точка во времени;Момент
tr-TR	Turkish (Turkey)	Jo-1 öztlenebilir çekirdek Ab.IgG:SçKons:Zmlı:Ser:Kant:İA Synonyms: Ak Ak.IgG Çekirdek İmmünölçüm, immünoassay
zh-CN	Chinese (China)	Jo-1 可提取性核抗体.IgG:任意型浓度:时间点:血清:定量型:免疫测定法 Synonyms: Ⅰ Ab.IgG;IgG;抗体 IgG Ab;自身抗体 ANA ENA Ab ENA Jo1 Ab ENA Jo-1 Ab ENA Jo1 Ab.IgG ENA Jo-1 Ab.IgG ENA Jo1 IgG ENA Jo-1 IgG ENA Jo1 抗体 ENA Jo-1 抗体 ENA Jo1 抗体.IgG ENA Jo-1 抗体.IgG ENA Jo1;ENA Jo-1;Jo-1 可提取性核 Ag;Jo-1 可提取性核抗原;可提取性核 Ag Jo1;可提取性核 Ag Jo-1;可提取性核抗原 Jo1;可提取性核抗原 Jo-1;组氨酰-tRNA 合成酶;组氨酰基-tRNA 合成酶 ENA 抗体 ENA;可提取性核 Ag;可提取性核抗原;可提取性核抗原（Extractable Nuclear Antigen，ENA）;可提取性细胞核;可提取性细胞核 Ag;可提取性细胞核抗原;盐水可提取性核 Ag;盐水可提取性核抗原;盐水可提取性细胞核 Ag;盐水可提取性细胞核抗原 I Jo1 可提取性核 Ab Jo-1 可提取性核 Ab Jo1 可提取性核 Ab.IgG Jo-1 可提取性核 Ab.IgG Jo1 可提取性核 Ag Ab Jo-1 可提取性核 Ag Ab Jo1 可提取性核 Ag Ab.IgG Jo-1 可提取性核 Ag Ab.IgG Jo1 可提取性核抗体 Jo1 可提取性核抗体.IgG Jo1 可提取性核抗原抗体 Jo-1 可提取性核抗原抗体 Jo1 可提取性核抗原抗体.IgG Jo-1 可提取性核抗原抗体.IgG NA 任意型浓度(单位体积);任意浓度;单位体积的任意单位数;人工型浓度免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验免疫球蛋白 G 可提取性核 Ab 可提取性核 Ag Jo1 Ab 可提取性核 Ag Jo-1 Ab 可提取性核 Ag Jo1 Ab.IgG 可提取性核 Ag Jo-1 Ab.IgG 可提取性核 Ag 之 Ab 可提取性核抗原 Jo1 IgG 可提取性核抗原 Jo-1 IgG 可提取性核抗原 Jo1 抗体可提取性核抗原 Jo-1 抗体可提取性核抗原 Jo1 抗体.IgG 可提取性核抗原 Jo-1 抗体.IgG 可提取性核抗原之抗体可用数量表示的;定量性;数值型;数量型;连续数值型标尺微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）抗 ENA 抗可提取性核 Ag 抗可提取性核抗原抗核 Ab 抗核抗体抗核抗体（Antinuclear antibody，ANA）时刻;随机;随意;瞬间核;胞核核心抗体IgG 核心抗原抗体.IgG 核心抗原抗体IgG 核抗体.IgG 核抗体IgG 核抗原抗体.IgG 核抗原抗体IgG 细胞核 Ab 细胞核 Ab.IgG 细胞核 IgG 胞核 Ab 胞核 Ab.IgG 胞核抗体胞核抗体.IgG

Example Units

Unit	Source
[IU]/mL	Example UCUM Units

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Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.