113275-2

Norhydrocodone [Mass/volume] in Saliva (oral fluid)

Active

Part Descriptions

LP102596-6   Norhydrocodone
Norhydrocodone is a metabolite of hydrocodone, a narcotic analgesic related to codeine, but more potent and more addicting by weight. It is used also as cough suppressant. Drug testing of pain patients provides objective information to health specialists regarding patient compliance, diversion, and concurrent illicit drug use. The interpretation of test results can be difficult however because of complex biotransformations of parent drug to metabolites that are also available commercially and may be abused. Additional testing for normetabolites, such as norhydrocodone, provides conclusive evidence that the parent drug was consumed and is helpful in interpreting the opiate drug source, and also reduces potential false negatives. PMID: 20036472 Source: Regenstrief LOINC, PMID: 20036472

LP7565-7   Saliva
Saliva is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. PMID: 17268583 Source: Regenstrief LOINC

LP262420-5   Saliva DRUG/TOX
Oral fluid (or saliva) is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. The test procedures that use oral fluid for drug screening are usually similar to those for other specimens but adapted for oral fluid. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Drugs present in oral fluid are often the parent drug rather than a metabolite and tests kits reflect those differences. Concentrations of cocaine, amphetamines and some opioids in oral fluid are either similar or higher than concentrations in plasma. The concentration of tetrahydrocannabinol (THC) in oral fluid is similar to that of plasma, though in cases where recent ingestion has occurred, levels may be higher due to the significant local absorption in the oral cavity. Confirmatory testing on oral fluid using liquid chromatography-mass spectrometry (LC-MS) is highly sensitive and specific even on relatively small sample sizes. An increased understanding of pharmacokinetics in oral fluid has flourished inover the last ten years has allowed the correlation of . As a result, the concentrations of various drugs in oral fluid have been correlated to blood concentrations and the effects they have on the individual. PMID: 17268583 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name

Norhydrocodone:MCnc:Pt:Saliva:Qn:

Long Common Name

Norhydrocodone [Mass/volume] in Saliva (oral fluid)

Short Name

Norhydrocodone Sal-mCnc

Display Name

Norhydrocodone (Sal) [Mass/Vol]

Consumer Name Alpha Get Info

Norhydrocodone, Saliva

Part Model Get Info

• Component

  Norhydrocodone
  LP102596-6

  • Analyte

    Norhydrocodone
    LP102596-6

    • Component Numerator

      Norhydrocodone
      LP102596-6

      • Component Numerator Core

        Norhydrocodone
        LP102596-6

      • Component Numerator Core Suffix

        NULL
         

    • Component Denominator

      NULL
       

      • Component Denominator Core

        NULL
         

      • Component Denominator Core Suffix

        NULL
         

  • Challenge

    NULL
     

  • Adjustment

    NULL
     

  • Count

    NULL
     

• Property

  MCnc
  LP6827-2

• Time

  Pt
  LP6960-1

  • Time Core

    Pt
    LP6960-1

  • Time Modifier

    NULL
     

• System

  Saliva
  LP7565-7

  • System Core

    Saliva
    LP7565-7

  • Super System

    NULL
     

• Scale

  Qn
  LP7753-9

• Method

  NULL
   

Basic Attributes

Class

DRUG/TOX

Type

Laboratory

First Released

Version 2.83

Last Updated

Version 2.83 (ADD)

Order vs. Observation

Both

Member of these Groups Get Info

Language Variants Get Info

Related Names

• DRUG/TOXICOLOGY
• Drugs
• Hydrocodone metabolite
• Level
• Mass concentration
• Oral fluid
• Point in time
• QNT
• Quan
• Quant
• Quantitative
• Random
• Sal

Example Units

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CodeSystem lookup

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=113275-2

LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.