Log In

Part Description

LP248423-8   Rotavirus B
Rotaviruses are non-enveloped, multilayered, icosahedral viruses composed of an outer layer, an inner layer, and a core. After the immature, double-layered virus is assembled in the host cell cytoplasm, they bud across the endoplasmic reticulum (ER) and acquire a temporary membrane that has on its surface the ER resident viral glycoproteins NSP4, VP4 and VP7. The virus loses its temporary membrane and the NSP4 glycoprotein as it moves toward the center of the ER cisternae. The VP4 and VP7 proteins are pushed to the outermost membrane layer and become the mature triple-layered rotavirus. The outer capsid glycoprotein VP7 is believed to be important for the attachment to and entry in the host cell. After it enters the host cell, the VP7 glycoprotein is lost. [UniProt: Q89865] When the host cell lyses, the mature virus are released. There are eight groups of rotavirus, A through H. Groups A, B, C, and H are associated with an acute gastroenteritis and are found in humans and animals. Groups D, E, F, and G are found only in animals. Rotavirus B (RVB) infect both humans and animals, and were the cause of severe diarrheal epidemics in China between 1982 and 1987. RVB has been isolated in lambs, pigs, cattle, goats and rats. India, Bangladesh, and Myanmar have also experienced acute outbreaks of gastroenteritis caused by infection with RVB. PMID: 2556635http://www.sciencedirect.com/science/article/pii/S004268220700400X?via%3Dihub PMID: 21985827 PMID: 24155654 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Rotavirus B RNA:PrThr:Pt:{Specimen}:Ord:{Molgen}
Long Common Name
Rotavirus B RNA [Presence] in Specimen by Molgen
Short Name
RVB RNA Spec Ql
Display Name
Rotavirus B RNA Molgen Ql (Specimen)
Consumer Name Alpha Get Info
Rotavirus B, Specimen

Part Model Get Info

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.83
Last Updated
Version 2.83 (ADD)
Order vs. Observation
Both

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=114674-5