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Part Descriptions

LP248050-9   Neisseria meningitidis sodC gene
Neisseria meningitides (Nm) is a species of gram-negative, aerobic bacteria. It is a commensal and pathogen only of humans, and can be carried asymptomatically in the nasopharynx. When found in cerebrospinal fluid it is the causative agent of cerebrospinal meningitis (meningitis, meningococcal). Nm can also be found in venereal discharges and blood. At least 13 serogroups have been described based on antigenic differences in the capsular polysaccharides; the ones causing most meningitis infections being A, B, C, Y, and W-135. Outbreaks caused by serogroup X meningococci have also been reported. Each serogroup can be further classified by serotype, serosubtype, and immunotype. (NLM, MeSH 2006) The two targets most frequently used in real-time PCR assays to identify Nm are the capsule transport gene (ctrA) and the Cu-An superoxide dismutase gene (sodC). sodC is found only in Nm and not in other species of Neisseria. sodC is highly sensitive and specific for the detection of Nm regardless of whether capsule genes are present or absent. ctrA is likely the target gene most often used to identify Nm, but because it is prone to rearrangement it does not detect roughly 16% of patients with Nm. PMID: 21573213 Source: Regenstrief LOINC

LP248050-9   Neisseria meningitidis sodC gene
Neisseria meningitidis is identified based on the species-specific targets sodC and ctrA. Individual Neisseria meningitidis serogroups are identified based on their serogroup-specific genes for capsule biosynthesis. Serogroups and the genes that identify them are as follows:
N. meningitidis serogroup A: sacB
N. meningitidis serogroup B: synD
N. meningitidis serogroup C: synE
N. meningitidis serogroup w135: synG
N. meningitidis serogroup X: xcbB
N. meningitidis serogroup Y: synF
https://www.cdc.gov/meningitis/lab-manual/chpt10-pcr.html Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Neisseria meningitidis sodC gene:PrThr:Pt:{Specimen}:Ord:{Molgen}
Long Common Name
Neisseria meningitidis sodC gene [Presence] in Specimen by Molgen
Short Name
N mening sodC Spec Ql
Display Name
N. meningitidis sodC gene Molgen Ql (Specimen)
Consumer Name Alpha Get Info
Neisseria meningitidis sodC gene, Specimen

Part Model Get Info

  • Component
    Neisseria meningitidis sodC gene
    LP248050-9
    • Analyte
      Neisseria meningitidis sodC gene
      LP248050-9
      • Component Numerator
        Neisseria meningitidis sodC gene
        LP248050-9
        • Component Numerator Core
          Neisseria meningitidis sodC gene
          LP248050-9
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    PrThr
    LP217195-9
  • Time
    Pt
    LP6960-1
  • System
    {Specimen}
    LP451871-0
  • Scale
    Ord
    LP7751-3
  • Method
    {Molgen}
    LP452305-8

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.83
Last Updated
Version 2.83 (ADD)
Order vs. Observation
Both

Member of these Groups Get Info

LOINC GroupGroup Name
LG41618-6Neisseria meningitidis

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=114780-0