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Part Description

LP262477-5   Escherichia coli Stx2 toxin stx2 gene
The Stx1 toxin A subunit is encoded by the stx1 gene [www.uniprot.org/uniprot/ ?query=stx1+escherichia+coli&sort=score] and the Stx2 toxin A subunit is encoded by the stx2 gene.[UniProt: K0JD26] Stx1a and Stx2a are produced by some serogroups of Escherichia coli (also known as Vero toxins and previously referred to as Shiga-like toxins) are two cytotoxins that cause hemorrhagic colitis (HC) and hemolytic uremic syndrome (HUS). The two toxins produce similar symptoms, but are immunologically unique. Both toxins are composed of a single copy of subunit A and five copies of subunit B. Stx1a and Stx1b induce host cell apoptosis by removing an adenine residue from the 28S rRNA of the 60S ribosome, with RNA-N-glycosidase activity provided by subunit A. The five B subunits bind to the host cell receptor present on endothelial cells. PMID: 25530917 Shigella toxin-producing Escherichia coli (STEC) has become a serious food-borne pathogen. Outbreaks of STEC have been associated with the consumption of pork products resulting in HC and HUS. STEC in swine has been demonstrated to cause edema disease. Epidemiological studies throughout the world have proven that STEC can be harbored and shed by domestic swine. PMID: 24397985 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Escherichia coli Stx2 toxin stx2 gene:PrThr:Pt:{Specimen}:Ord:{Molgen}
Long Common Name
Escherichia coli Stx2 toxin stx2 gene [Presence] in Specimen by Molgen
Short Name
EC stx2 gene Spec Ql
Display Name
E. coli stx2 gene Molgen Ql (Specimen)
Consumer Name Alpha Get Info
Escherichia coli stx2 toxin stx2 gene, Specimen

Part Model Get Info

  • Component
    Escherichia coli Stx2 toxin stx2 gene
    LP262477-5
    • Analyte
      Escherichia coli Stx2 toxin stx2 gene
      LP262477-5
      • Component Numerator
        Escherichia coli Stx2 toxin stx2 gene
        LP262477-5
        • Component Numerator Core
          Escherichia coli Stx2 toxin stx2 gene
          LP262477-5
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    PrThr
    LP217195-9
  • Time
    Pt
    LP6960-1
  • System
    {Specimen}
    LP451871-0
  • Scale
    Ord
    LP7751-3
  • Method
    {Molgen}
    LP452305-8

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.83
Last Updated
Version 2.83 (ADD)
Order vs. Observation
Both

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=115079-6